LOCUS BC024256 1949 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens F-box and leucine-rich repeat protein 18, mRNA (cDNA
clone MGC:13101 IMAGE:3954975), complete cds.
ACCESSION BC024256
VERSION BC024256.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1949)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1949)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 18 Row: m Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21361980
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..1949
/db_xref="H-InvDB:HIT000039791"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:13101 IMAGE:3954975"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1949
/gene="FBXL18"
/gene_synonym="Fbl18"
/db_xref="GeneID:80028"
/db_xref="HGNC:HGNC:21874"
/db_xref="MIM:609084"
CDS 95..1192
/gene="FBXL18"
/gene_synonym="Fbl18"
/codon_start=1
/product="FBXL18 protein"
/protein_id="AAH24256.1"
/db_xref="GeneID:80028"
/db_xref="HGNC:HGNC:21874"
/db_xref="MIM:609084"
/translation="MASSGEDISNDDDDMHPAAAGMADGVHLLGFSDEILLHILSHVP
STDLILNVRRTCRKLAALCLDKSLIHTVLLQKDYQASEDKVRQLVKEIGREIQQLSMA
GCYWLPGSTVEHVARCRSLVKVNLSGCHLTSLRLSKMLSALQHLRSLAIDVSPGFDAS
QLSSECKATLSRVRELKQTLFTPSYGVVPCCTSLEKLLLYFEILDRTREGAILSGQLM
VGQSNVPHYQNLRVFYARLAPGYINQEVVRLYLAVLSDRTPQNLHAFLISVPGSFAES
GATKNLLDSMARNVVLDALQLPKSWLNGSSLLQHMKFNNPFYFSFSRCTLSGGHLIQQ
VINGGKDLRSLASLNLSGCVHCLSPDSLLCR"
BASE COUNT 428 a 607 c 545 g 369 t
ORIGIN
1 gcggtggacg cgccggcttc gagcatccct agccgggcag gtgggaggca cggggttgcg
61 gatcccgcgg ccgcggttcg gacccgccgg cgacatggcc agctccggag aggacatatc
121 caatgatgat gatgacatgc accctgcagc agccgggatg gcagacgggg tccacctcct
181 agggttctct gatgagatcc tccttcacat cctgagtcac gtccccagca cagatctgat
241 tctgaacgtc cggcgtacct gtcggaagct tgcagccctg tgccttgaca agagcctcat
301 ccacaccgtg ttgctgcaaa aggactatca ggcgagcgag gacaaagtga ggcagctggt
361 gaaggagatc ggccgggaga tccagcagct gagcatggct ggctgctact ggctgcctgg
421 ctccaccgtg gaacacgtgg cccgctgccg cagcctggtg aaggtgaacc tctcgggctg
481 ccacctcact tccctgcgcc tctccaagat gctctcggcc ctgcagcacc tgcgctcgct
541 ggccatcgac gtgagccccg gcttcgacgc cagccagctg agcagcgagt gcaaggccac
601 cctgagccgc gtgcgggagc tcaagcagac gctgttcact ccctcctacg gcgtggtgcc
661 ctgctgcacc agcctagaga agctgctgct ctacttcgag attctggacc gcacgcgcga
721 gggcgccatc ctctcgggcc agcttatggt gggccagagc aacgtgccgc actaccagaa
781 cctgcgggtc ttctatgcgc gcctggcccc cggctacatc aaccaggagg tggtgcggct
841 ctacctggct gtgcttagcg accgcactcc tcagaacctc cacgccttcc tcatctccgt
901 ccctggcagc ttcgcggaga gcggcgccac caagaacctc ctggactcca tggcgcgcaa
961 tgtcgtgctg gatgccctgc agctgcccaa gtcctggctg aacggctctt ccctcctgca
1021 gcacatgaaa ttcaacaacc cgttctactt cagtttcagc cgctgtaccc tgtcaggcgg
1081 ccatctgatc cagcaggtca tcaacggcgg gaaggacctg cggagcctgg ccagcttgaa
1141 cctcagcggc tgcgtccact gcctgtcccc agactcgctg ctctgtcgct gactccgcgc
1201 cgcgcgccga ccgcgcgccc gcccagccgg ccatgcacgc agtgccgcgc ggctttggca
1261 agaaagtgcg tgtgggcgtg cagtcctgtc ccagcccctt ctcgggccag gcgtgccccc
1321 agccctcctc cgtgttctgg tctctgctga agaacctgcc cttccctggg aaggtccatg
1381 cgcgttcctg gggaaatcga tacacattcg gctttgttag aataacgcga aacattaaaa
1441 cccagaaagg attcttaagg ctggagtagc aatcacatga ccccatttca aatgacttca
1501 tttaagactt taaaaatact cagctgggcg cgatggctca cgcctgtaat cccggcactt
1561 tgggaggctg aggtgggtgg atcacgaggt caggagttca agaccagcct ggccaacatg
1621 gtgaaacccc atctctacta aaaatacaaa aattagctgg gcgtggtggc gggcgcctgt
1681 aatcctagct actcaggagg ctgaggcagg agaatcgttt gaacctggga ggcggaggtt
1741 gcagtgagcc gagatcacac cattgcactc cagcctggac aacagggtga gactccgcct
1801 caaaaaaaaa aaaaaaaaaa atatatatat atatatatat attcaacaca ctttgggagg
1861 atcacttgag cccaggagtt tgagatcagc ctgggcaaca cagggatacc ccatctctga
1921 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
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