LOCUS BC024159 3329 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens leucine rich repeat containing 8 family, member D,
mRNA (cDNA clone MGC:16497 IMAGE:3958069), complete cds.
ACCESSION BC024159
VERSION BC024159.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3329)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3329)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC024159.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 25 Row: l Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34222198.
FEATURES Location/Qualifiers
source 1..3329
/db_xref="H-InvDB:HIT000050882"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:16497 IMAGE:3958069"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3329
/gene="LRRC8D"
/gene_synonym="FLJ10470"
/db_xref="GeneID:55144"
/db_xref="HGNC:HGNC:16992"
CDS 380..2956
/gene="LRRC8D"
/gene_synonym="FLJ10470"
/codon_start=1
/product="leucine rich repeat containing 8 family, member
D"
/protein_id="AAH24159.2"
/db_xref="GeneID:55144"
/db_xref="HGNC:HGNC:16992"
/translation="MFTLAEVASLNDIQPTYRILKPWWDVFMDYLAVVMLMVAIFAGT
MQLTKDQVVCLPVLPSPVNSKAHTPPGNAEVTTNIPKMEAATNQDQDGRTTNDISFGT
SAVTPDIPLRATYPRTDFALPNQEAKKEKKDPTGRKTNLDFQQYVFINQMCYHLALPW
YSKYFPYLALIHTIILMVSSNFWFKYPKTCSKVEHFVSILGKCFESPWTTKALSETAC
EDSEENKQRITGAQTLPKHVSTSSDEGSPSASTPMINKTGFKFSAEKPVIEVPSMTIL
DKKDGEQAKALFEKVRKFRAHVEDSDLIYKLYVVQTVIKTAKFIFILCYTANFVNAIS
FEHVCKPKVEHLIGYEVFECTHNMAYMLKKLLISYISIICVYGFICLYTLFWLFRIPL
KEYSFEKVREESSFSDIPDVKNDFAFLLHMVDQYDQLYSKRFGVFLSEVSENKLREIS
LNHEWTFEKLRQHISRNAQDKQELHLFMLSGVPDAVFDLTDLDVLKLELIPEAKIPAK
ISQMTNLQELHLCHCPAKVEQTAFSFLRDHLRCLHVKFTDVAEIPAWVYLLKNLRELY
LIGNLNSENNKMIGLESLRELRHLKILHVKSNLTKVPSNITDVAPHLTKLVIHNDGTK
LLVLNSLKKMMNVAELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHL
KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNN
ISMIPIEIGLLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLS
QLTQLELKGNCLDRLPAQLGQCRMLKKSGLVVEDHLFDTLPLEVKEALNQDINIPFAN
GI"
BASE COUNT 1001 a 711 c 707 g 910 t
ORIGIN
1 ctcttgggag cgggacttct gctcaaatcc tgtccagggg cttgaaaagg aggagaattg
61 ggggtggttg ccgggaggac cagcacctcc agttactgga gggttgatag gggccttctc
121 ctttccgtcc ccctttacta gggggtatcc cttgcagata aatgagattt tttgatttct
181 taaaaagcca gctgcagtga agaagaactg ctgcaggtcg aggggaagag aggaagtgca
241 cggctgtcta taacgtgctg ccgggtctca ggatggagga gtgaagtctc ctgtcgccgt
301 ggttccagcc tccggagctc gcccaagccg cgtccccaga gagcgccctg agagaacagg
361 gtggccgctt ggtccaggaa tgtttaccct tgcggaagtt gcatcactta atgacattca
421 gccaacttac cgaatcctga aaccatggtg ggatgtgttt atggattacc tagctgttgt
481 tatgttaatg gtagccatct ttgcaggaac catgcaactt accaaagatc aggtggtctg
541 tttgccagta ttgccatctc ctgtaaattc aaaggcacat acaccaccag gaaatgccga
601 ggtcaccacc aacatcccaa agatggaagc agccaccaac caagaccaag atgggcggac
661 aacaaacgac atttcctttg ggacatctgc tgtgacacct gacatacctc tcagagccac
721 atatcctcgc acagatttcg cacttccaaa tcaggaggca aagaaagaga agaaagatcc
781 aacaggtcga aaaacaaact tggattttca gcaatatgta tttattaatc aaatgtgtta
841 ccatctggcc cttccgtggt attctaagta ctttccatac ctagctctta tacatactat
901 tattctcatg gtcagtagca acttttggtt caaatatccc aaaacatgct caaaagtaga
961 acattttgtt tcaatattag gaaagtgctt tgaatcccct tggacgacaa aagcgttgtc
1021 tgagacagca tgcgaagact cagaggaaaa caagcagaga ataacaggtg cccagactct
1081 accaaagcat gtttctacca gcagtgatga agggagcccc agtgccagta caccaatgat
1141 caataaaact ggctttaaat tttcagctga gaagcctgtg attgaagttc ccagcatgac
1201 aatcctggat aaaaaggatg gagagcaggc caaagccctg tttgagaaag tgaggaagtt
1261 ccgtgcccat gtggaagata gtgacttgat ctataaactc tatgtggtcc aaacagttat
1321 caaaacagcc aagttcattt ttattctctg ctatacagcg aactttgtca acgcaatcag
1381 ctttgaacac gtctgcaagc ccaaagttga gcatctgatt ggttatgagg tatttgagtg
1441 cacccacaat atggcttaca tgttgaaaaa gcttctcatc agttacatat ccattatttg
1501 tgtttatggc tttatctgcc tctacactct cttctggtta ttcaggatac ctttgaagga
1561 atattctttc gaaaaagtca gagaagagag cagttttagt gacattccag atgtcaaaaa
1621 cgattttgcg ttccttcttc acatggtaga ccagtatgac cagctatatt ccaagcgttt
1681 tggtgtgttc ttgtcagaag ttagtgaaaa taaacttagg gaaattagtt tgaaccatga
1741 gtggacattt gaaaaactca ggcagcacat ttcacgcaac gcccaggaca agcaggagtt
1801 gcatctgttc atgctgtcgg gggtgcccga tgctgtcttt gacctcacag acctggatgt
1861 gctaaagctt gaactaattc cagaagctaa aattcctgct aagatttctc aaatgactaa
1921 cctccaagag ctccacctct gccactgccc tgcaaaagtt gaacagactg cttttagctt
1981 tcttcgcgat cacttgagat gccttcacgt gaagttcact gatgtggctg aaattcctgc
2041 ctgggtgtat ttgctcaaaa accttcgaga gttgtactta ataggcaatt tgaactctga
2101 aaacaataag atgataggac ttgaatctct ccgagagttg cggcacctta agattctcca
2161 cgtgaagagc aatttgacca aagttccctc caacattaca gatgtggctc cacatcttac
2221 aaagttagtc attcataatg acggcactaa actcttggta ctgaacagcc ttaagaaaat
2281 gatgaatgtc gctgagctgg aactccagaa ctgtgagcta gagagaatcc cacatgctat
2341 tttcagcctc tctaatttac aggaactgga tttaaagtcc aataacattc gcacaattga
2401 ggaaatcatc agtttccagc atttaaaacg actgacttgt ttaaaattat ggcataacaa
2461 aattgttact attcctccct ctattaccca tgtcaaaaac ttggagtcac tttatttctc
2521 taacaacaag ctcgaatcct taccagtggc agtatttagt ttacagaaac tcagatgctt
2581 agatgtgagc tacaacaaca tttcaatgat tccaatagaa ataggattgc ttcagaacct
2641 gcagcatttg catatcactg ggaacaaagt ggacattctg ccaaaacaat tgtttaaatg
2701 cataaagttg aggactttga atctgggaca gaactgcatc acctcactcc cagagaaagt
2761 tggtcagctc tcccagctca ctcagctgga gctgaagggg aactgcttgg accgcctgcc
2821 agcccagctg ggccagtgtc ggatgctcaa gaaaagcggg cttgttgtgg aagatcacct
2881 ttttgatacc ctgccactcg aagtcaaaga ggcattgaat caagacataa atattccctt
2941 tgcaaatggg atttaaacta agataatata tgcacagtga tgtgcaggaa caacttccta
3001 gattgcaagt gctcacgtac aagttattac aagataatgc attttaggag tagatacatc
3061 ttttaaaata aaacagagag gatgcataga aggctgatag aagacataac tgaatgttca
3121 atgtttgtag ggttttaagt cattcatttc caaatcattt ttttttttct tttggggaaa
3181 gggaaggaaa aattataatc actaatcttg gttcttttta aattgtttgt aacttggatg
3241 ctgccgctac tgaatgttta caaattgctt gcctgctaaa gtaaatgatt aaattgacat
3301 tttcttacta taaaaaaaaa aaaaaaaaa
//