LOCUS BC024043 4509 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens PAN2 poly(A) specific ribonuclease subunit homolog (S.
cerevisiae), mRNA (cDNA clone MGC:1971 IMAGE:3357890), complete
cds.
ACCESSION BC024043
VERSION BC024043.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4509)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4509)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (11-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 6 Row: g Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 41281526.
FEATURES Location/Qualifiers
source 1..4509
/db_xref="H-InvDB:HIT000050879"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1971 IMAGE:3357890"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..4509
/gene="PAN2"
/gene_synonym="hPAN2"
/db_xref="GeneID:9924"
/db_xref="HGNC:HGNC:20074"
CDS 220..3816
/gene="PAN2"
/gene_synonym="hPAN2"
/codon_start=1
/product="PAN2 poly(A) specific ribonuclease subunit
homolog (S. cerevisiae)"
/protein_id="AAH24043.1"
/db_xref="GeneID:9924"
/db_xref="HGNC:HGNC:20074"
/translation="MNFEGLDPGLAEYAPAMHSALDPVLDAHLNPNLLQNVELDPEGV
ALEALPVQESVHIMEGVYSELHSVVAEVGVPVSVSHFDLHEEMLWVGSHGGHATSFFG
PALERYSSFQVNGSDDIRQIQSLENGILFLTKNNLKYMARGGLIIFDYLLDENEDMHS
LLLTDSSTLLVGGLQNHILEIDLNTVQETQKYAVETPGVTIMRQTNRFFFCGHTSGKV
SLRDLRTFKVEHEFDAFSGSLSDFDVHGNLLAACGFSSRLTGLACDRFLKVYDLRMMR
AITPLQVHVDPAFLRFIPTYTSRLAIISQSGQCQFCEPTGLANPADIFHVNPVGPLLM
TFDVSASKQALAFGDSEGCVHLWTDSPEPSFNPYSRETEFALPCLVDSLPPLDWSQDL
LPLSLIPVPLTTDTLLSDWPAANSAPAPRRAPPVDAEILRTMKKVGFIGYAPNPRTRL
RNQIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDF
KHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHM
LDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWNRFILTQL
HQDMQELEIPQAYRGAGGSSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLF
TLSYPDDKTGKNYDFAQVLKRSICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVIN
CEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLVCPSIE
ELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHIL
DSRTGGSLVAHIKVGETYHQRKEGVTHQQWYLFNDFLIEPIDKHEAVQFDMNWKVPAI
LYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVG
LDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQ
VVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVIN
LMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKY
LELSKNGTEPESFHKVLKGLYEKGRKMDWKVPEPEGQTSPKNAAVFSSVLAL"
BASE COUNT 1102 a 1142 c 1127 g 1138 t
ORIGIN
1 gagaactggg gaaactggaa tttcccgcgg agctgacagc gcttgcgctc cccctactcg
61 ttctaattcc acgcgctcca aaatatccgc catggagaaa tcttggccag gatgtccatt
121 ctaggcccat cggtgctgtc ttgctgaagg ttgggtcagg catctaaagg gactgtggta
181 agggagggtg tgacacaggt gtaagctgcc atcgtcatca tgaactttga gggtctggac
241 cctggactgg cagaatatgc cccagccatg cattctgccc tggaccctgt cttggatgcc
301 cacctgaacc caaatctgct acagaatgtg gagctggacc cagagggagt ggccttggag
361 gctcttcccg tccaggaatc agtgcacata atggaaggtg tctactctga attgcacagc
421 gtggtggctg aagtgggtgt acctgtttcc gtctcccact ttgacttgca cgaggagatg
481 ctgtgggtgg ggagccacgg gggccatgcc acttcatttt ttggcccagc cttggagcgc
541 tactcatcct ttcaagtcaa tggcagtgat gatattcggc agatccagag cctggagaat
601 ggtatccttt ttctcaccaa gaacaacctc aagtatatgg cccgtggggg cctcattata
661 tttgattacc tgctggatga gaatgaggat atgcacagtc tcctactgac tgacagcagc
721 actctactcg ttggtgggct gcagaatcac atactagaga ttgatcttaa cactgtccag
781 gagactcaga agtatgcagt agagacgcct ggagtcacca tcatgagaca gacaaatcgc
841 ttcttcttct gcggccacac gtctggcaag gtttccctga gagacctccg tacttttaag
901 gtggaacatg agtttgatgc cttctcagga agtctgtcag actttgatgt gcatggcaac
961 ctgctagctg cctgtggctt ctccagccgc ctcactggcc tggcctgcga ccgtttcctc
1021 aaggtgtatg atttgcgcat gatgcgtgcc atcacaccac ttcaagtaca tgtggatcct
1081 gccttcttgc gcttcattcc tacatatact tctcgtcttg ctatcatctc tcagtcaggg
1141 cagtgccaat tctgtgaacc cacaggcctg gccaacccag ccgatatctt tcatgtgaat
1201 cctgtggggc ctctgctaat gacatttgat gtgtcagcca gcaagcaggc tctggccttt
1261 ggggattctg agggctgtgt gcacctctgg actgattccc cggagccttc cttcaacccc
1321 tactcccgtg agactgagtt tgctttgccg tgtctcgtgg actcactgcc tcctctggac
1381 tggagccagg acctgctgcc tctttccctc atccctgtcc cactcaccac tgacacactt
1441 ctctctgatt ggcctgctgc caactctgct ccagctccca ggcgagcacc acccgtggat
1501 gcagagattc tgcgcaccat gaagaaggtg ggcttcattg gctatgcgcc caatccccgc
1561 accaggctgc gcaatcagat accctacaga ctcaaggagt cagacagtga atttgacagc
1621 ttcagccagg tcactgagtc accagtagga cgagaagagg aaccacatct ccacatggtt
1681 tctaagaaat accgcaaggt gaccatcaaa tattccaagc tagggctgga ggactttgac
1741 ttcaaacact acaataagac cttgtttgct ggattagagc cccacattcc caacgcctac
1801 tgtaactgca tgatccaggt gctctatttc ctggagcctg tacgctgtct aattcaaaac
1861 cacctttgcc agaaggagtt ctgtctggca tgtgagctgg gcttcctgtt tcacatgttg
1921 gacctctctc gtggtgaccc ttgccagggc aataattttc ttcgggcatt ccgtactatt
1981 cctgaggcct cagccctcgg tctaatcctg gctgactcag atgaggcctc aggcaagggc
2041 aatctggcca ggctcattca gaggtggaat cgcttcattc tcactcaact gcatcaagat
2101 atgcaggagc tggaaatacc acaggcttat cgaggtgctg gaggcagcag cttttgctca
2161 tcgggggact ctgttattgg gcagctcttc agctgtgaga tggagaactg cagcctctgc
2221 cgctgtggca gtgagaccgt gcgagcctca tccactctgc ttttcacact ctcctaccct
2281 gatgataaaa ctgggaagaa ctatgacttt gctcaggtgc tgaagcgaag catctgcctg
2341 gaccagaata cacaggcctg gtgtgacacc tgtgaaaagt accagcccac gattcagacc
2401 cgcaacatcc gccatctgcc agatattctt gtcatcaatt gtgaggtgaa cagctcaaaa
2461 gaggctgatt tctggagaat gcaggctgag gttgccttca agatggcagt aaagaaacac
2521 ggtggggaaa tctccaagaa caaggaattt gctttggctg attggaagga actagggagt
2581 ccagagggtg tgctggtgtg tccctccatt gaggagttga agaacgtctg gcttcctttc
2641 tccattcgca tgaagatgac caaaaacaaa gggctggatg tttgcaattg gactgatggg
2701 gatgagatgc agtggggccc agccagggca gaggaggagc atggtgtcta tgtgtatgac
2761 ctgatggcta ctgtggtaca catcctggac tcacgcacag ggggcagcct ggtggctcac
2821 atcaaagttg gagagaccta ccaccagcgc aaggagggcg ttactcacca gcagtggtat
2881 ctgttcaatg actttcttat tgaacctatt gataagcatg aagctgtgca gtttgacatg
2941 aattggaaag tacctgcaat cctttattat gtcaaacgga atctcaattc cagatacaac
3001 ctgaacatca agaaccctat tgaggcaagt gtcttgctgg ctgaagcctc gctggcacgg
3061 aagcagcgga aaacacatac tacctttatt ccactgatgc tgaatgagat gccacagatt
3121 ggggacctgg tgggtctgga tgctgagttt gtcaccctta atgaggagga agcagagtta
3181 cgcagtgatg gtaccaagtc taccattaaa ccaagccaga tgtcagtagc caggattacc
3241 tgtgttcggg gccagggacc caatgagggt atccccttca ttgatgacta catctctacc
3301 caggagcagg tggtggatta cttgactcaa tactcgggta taaagcctgg tgacctcgat
3361 gccaaaattt cctccaagca cctaacaact ctcaagtcta cctacttaaa gcttcgtttt
3421 ctcattgaca ttggagtcaa gtttgtgggt catggcctgc agaaggactt ccgggtcatc
3481 aacctgatgg tgcccaagga ccaagtcctt gacactgtct acctgttcca tatgccccga
3541 aaacgaatga tttccctgcg attccttgct tggtactttc tggacctgaa gattcaaggg
3601 gaaacccatg acagtattga ggatgcccgc acagcccttc agctgtaccg aaagtatctg
3661 gagctaagca aaaatggcac tgagcctgag tctttccaca aggtgctcaa gggtctttat
3721 gagaagggca gaaagatgga ctggaaggtg cctgagcctg agggccaaac aagtcccaag
3781 aatgcagctg tcttctcctc agtgctggcg ctctgactac ccttcccaaa gaaccacggc
3841 cctctccctt tactgttcta tagccccaga actgggagat ggcttcctaa gttggctata
3901 ccttgtccac ttccagtact ggacgtgctc agggtctagg gtcacagatg gtgctattaa
3961 ttgaactgga acacagcaga attgttgcaa aggttctagg agccagattc attccttctt
4021 cattctttgc aaaacagtgg tacagacatg gagtctagaa ttgacccaga tggaaagtaa
4081 ttggtattct taatatcctg ggtgactaat atccaggcag agaagctcct ggaaccataa
4141 ctgtaagttc ctagctggct agggattgaa gtcctggaca gtgacagagg ataccacagt
4201 agttcaagac ttagcacaag tcaccaactg cttcagggat acctggaggg gccagcaagt
4261 agagtgttgg tggcccaagc aaaccagtgt tgccaatacc attgccaaaa gggcctttgg
4321 atcctggaca aagcttggct gccggcttca tttattcctg ctgatggctg agaagcatct
4381 gtcttccatc ccacttgcct gtcccaagtt ttgttccatt ttttaaaaat ttgttgtaaa
4441 ctgcatgttt tataaaataa aaataaaata tcgtttgtta tttatctcaa aaaaaaaaaa
4501 aaaaaaaaa
//