LOCUS BC023645 3134 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens FYVE, RhoGEF and PH domain containing 2, mRNA (cDNA
clone MGC:29450 IMAGE:5087501), complete cds.
ACCESSION BC023645
VERSION BC023645.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3134)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3134)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC023645.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 39 Row: o Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34222232.
FEATURES Location/Qualifiers
source 1..3134
/db_xref="H-InvDB:HIT000050859"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:29450 IMAGE:5087501"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_99"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene 1..3134
/gene="FGD2"
/gene_synonym="ZFYVE4"
/db_xref="GeneID:221472"
/db_xref="HGNC:HGNC:3664"
/db_xref="MIM:605091"
CDS 172..2139
/gene="FGD2"
/gene_synonym="ZFYVE4"
/codon_start=1
/product="FYVE, RhoGEF and PH domain containing 2"
/protein_id="AAH23645.1"
/db_xref="GeneID:221472"
/db_xref="HGNC:HGNC:3664"
/db_xref="MIM:605091"
/translation="MKGASEEKLASVSNLVTVFENSRTPEAAPRGHRLEDVHHRPECR
PPESPGPREKTNVGEAVGSEPRTVSRRYLNSLKNKLSSEAWRKSCQPVTLSGSGTQEP
EKKIVQELLETEQAYVARLHLLDQVFFQELLKTARSSKAFPEDVVRVIFSNISSIYQF
HSQFFLPELQRRLDDWTANPRIGDVIQKLAPFLKMYSEYVKNFERAAELLATWTDKSP
LFQEVLTRIQSSEASGSLTLQHHMLEPVQRIPRYELLLKEYIQKLPAQAPDQADAQKA
LDMIFSAAQHSNAAITEMERLQDLWEVYQRLGLEDDIVDPSNTLLREGPVLKISFRRN
DPMERYLFLFNNMLLYCVPRVIQVGAQFQVRTRIDVAGMKVRELMDAEFPHSFLVSGK
QRTLELQARSQEEMISWMQAFQAAIDQIEKRNETFKAAAQGPEGDIQEQELQSEELGL
RAPQWVRDKMVTMCMRCQEPFNALTRRRHHCRACGYVVCARCSDYRAELKYDDNRPNR
VCLHCYAFLTGNVLPEAKEDKRRGILEKGSSATPDQSLMCSFLQLIGDKWGKSGPRGW
CVIPRDDPLVLYVYAAPQDMRAHTSIPLLGYQVTVGPQGDPRVFQLQQSGQLYTFKAE
TEELKGRWVKAMERAASGWSPSWPNDGDLSD"
BASE COUNT 727 a 890 c 863 g 654 t
ORIGIN
1 ctttcttcac tctgaagcca agagccgacc ttctgagccc tcaagaaaga tcagaacaga
61 ttcatgggtg atttagccta tctgtcccag gccagcgtgg ctgagtgtgc tggctggagg
121 cctctctctc tgcttcgagg gtagctgaga tccaccccgg aaaccggcag gatgaagggg
181 gcaagtgagg agaagctggc atctgtgtcc aacctggtca ctgtgtttga gaatagcagg
241 accccagaag cagcacccag aggccacagg ctagaggacg tgcatcaccg ccctgagtgc
301 aggcctcccg agtccccagg accacgggag aagacgaatg tcggggaggc cgtggggtct
361 gagcccagga cagtcagcag gaggtacctg aactccctga agaacaagct gtccagcgaa
421 gcctggagga aatcttgcca gcctgtgacc ctctcaggat cggggacgca ggagccagag
481 aagaagatcg tccaggagct gctggagaca gagcaggcct atgtggcgcg cctccacctg
541 ctagaccagg tgtttttcca ggagctgctg aagacagccc gcagcagcaa ggccttccca
601 gaggatgtgg tcagggtcat cttctccaac atctcctcca tctatcagtt ccattctcag
661 ttcttcctcc cagagctgca gcggcgcctg gacgactgga cagctaaccc ccgcatcggt
721 gacgtgatcc agaagctggc ccccttcctg aagatgtaca gtgagtatgt caagaacttt
781 gagcgagcgg ctgagctgct ggccacctgg accgacaagt ctccactctt ccaggaggtt
841 ctcactcgca tccagagcag cgaggcttcg ggcagcctga ccctgcagca ccacatgctg
901 gaaccagtgc agagaattcc acgttacgag ctgctgctca aggagtacat ccagaagctg
961 ccagcccagg ccccagacca ggccgatgcc cagaaagccc tggacatgat cttctcagct
1021 gcccagcact ccaatgcagc catcactgag atggagcggc tgcaggacct gtgggaggtg
1081 taccagcgcc tgggcctcga ggacgacata gtagacccct ctaacaccct gctccgtgag
1141 ggcccggtcc tcaagatctc cttccgccgc aacgacccca tggagcgcta ccttttcttg
1201 ttcaacaaca tgctgctcta ctgtgtgccc agggtgatcc aggtgggcgc ccagttccag
1261 gtgaggaccc gcatcgatgt ggccgggatg aaggtgcggg agctgatgga tgctgagttt
1321 ccccactcct tcctggtgtc cgggaagcag cgcaccctgg agctgcaagc ccggtcccag
1381 gaggaaatga tttcctggat gcaggccttc caagcagcca ttgaccaaat cgagaagcgg
1441 aatgaaacct tcaaggctgc ggcccagggg cctgagggag acatccagga gcaggagctg
1501 cagtctgagg agctgggcct ccgggcaccg cagtgggtcc gggacaagat ggtgaccatg
1561 tgcatgcgct gccaggagcc cttcaacgct ctgacgcgcc gtcgccacca ctgccgggcc
1621 tgcggctatg tggtgtgtgc caggtgctcc gactaccggg ccgaactgaa atacgacgac
1681 aacaggccca accgagtctg cctccactgc tacgcattcc tcactggaaa tgtgctgcct
1741 gaggccaagg aggacaagag gcggggcatc ctggagaaag ggtcctcagc cacgcctgac
1801 cagagcctga tgtgcagctt cctgcagctc atcggggaca agtggggcaa gagcggcccc
1861 cggggctggt gtgtgatccc tcgggatgac cccctcgtgc tctatgtcta tgctgcccct
1921 caggacatga gggctcacac ctccatcccc ctgctgggct accaggtgac tgttgggccc
1981 cagggggacc ctcgggtctt ccagctacag cagtcaggcc agctctacac cttcaaggcc
2041 gagacggagg agctgaaggg ccgctgggtg aaggccatgg agcgggcggc cagtggctgg
2101 agccccagct ggcccaacga tggggacctg tccgactgag ccactgccag ccgctctcct
2161 gcccacctct ccccaccctg aacccagctc ctgccacaga ctgaccctgt ggcctcagtg
2221 acccactgcc ccaagtggtg ctttcagaga attgattcag ccatctgcgc ccaggccacg
2281 tgtcccgatc tgggattaga aaatatgggt ccattccttt ctagaaaggg gacaaccaag
2341 tgtctcagtt tgccttgcgg ggagggggct cctgggccat gggacttcca gtgctaaaac
2401 tgggaaagcc ccaggtaacc ccggactggt ggtcaccata gtatggtttt tcatttgtat
2461 ctcctgggga gcttttaaag agtactggtg aaaaacacat agtaaattaa ttttaaaaat
2521 gtaaaaaaca atgcctgtac tgaagtacca ccaccgattt aaatgggctg agttggggga
2581 ggcatggggt cttttttttt tttttttttt tttttttttt tttttttttt tttttttttt
2641 tttttttgag acagagtctt actctgtttc ccaggctgga gtgcacaaac atggctcact
2701 acagcctcgc tctcccgggc tccagtgatc ctcccgcctc agcctcccaa gtagctggga
2761 ttataggtgt gtgccactgt gccaagctaa tttttttatt ttttgtagag atgggatttc
2821 accatgttac tcaggctggt ctcaaactcc cagcctcaag cgatgctccc acctccacct
2881 cccaaagtgc tgggattaca ggcgtgagcc accatacctg gcgcatgcat attttttaag
2941 agtacccact ggagtctaat atatagcctg ggttacctgg gatgaagaat aaagagagca
3001 aactaccaca accaatggtt gagcccctgt caagtgccag tcatgatagt agtaataata
3061 ataataaaca tctattgggc cagaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3121 aaaaaaaaaa aaaa
//