LOCUS BC023633 2130 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens frataxin, mRNA (cDNA clone MGC:23075 IMAGE:4842134),
complete cds.
ACCESSION BC023633
VERSION BC023633.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2130)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2130)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC023633.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 33 Row: n Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 31742515.
FEATURES Location/Qualifiers
source 1..2130
/db_xref="H-InvDB:HIT000090827"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23075 IMAGE:4842134"
/tissue_type="Eye, normal, pigmented retinal epithelium"
/clone_lib="NIH_MGC_43"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2130
/gene="FXN"
/gene_synonym="FA"
/gene_synonym="FARR"
/gene_synonym="MGC57199"
/gene_synonym="X25"
/db_xref="GeneID:2395"
/db_xref="HGNC:HGNC:3951"
/db_xref="MIM:606829"
CDS 29..661
/gene="FXN"
/gene_synonym="FA"
/gene_synonym="FARR"
/gene_synonym="MGC57199"
/gene_synonym="X25"
/codon_start=1
/product="frataxin"
/protein_id="AAH23633.1"
/db_xref="GeneID:2395"
/db_xref="HGNC:HGNC:3951"
/db_xref="MIM:606829"
/translation="MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRT
DIDATCTPRRASSNQRGLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEET
LDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPS
SGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA"
BASE COUNT 597 a 480 c 503 g 550 t
ORIGIN
1 gcggagcggg cggcagaccc ggagcagcat gtggactctc gggcgccgcg cagtagccgg
61 cctcctggcg tcacccagcc cggcccaggc ccagaccctc acccgggtcc cgcggccggc
121 agagttggcc ccactctgcg gccgccgtgg cctgcgcacc gacatcgatg cgacctgcac
181 gccccgccgc gcaagttcga accaacgtgg cctcaaccag atttggaatg tcaaaaagca
241 gagtgtctat ttgatgaatt tgaggaaatc tggaactttg ggccacccag gctctctaga
301 tgagaccacc tatgaaagac tagcagagga aacgctggac tctttagcag agttttttga
361 agaccttgca gacaagccat acacgtttga ggactatgat gtctcctttg ggagtggtgt
421 cttaactgtc aaactgggtg gagatctagg aacctatgtg atcaacaagc agacgccaaa
481 caagcaaatc tggctatctt ctccatccag tggacctaag cgttatgact ggactgggaa
541 aaactgggtg tactcccacg acggcgtgtc cctccatgag ctgctggccg cagagctcac
601 taaagcctta aaaaccaaac tggacttgtc ttccttggcc tattccggaa aagatgcttg
661 atgcccagcc ccgttttaag gacattaaaa gctatcaggc caagacccca gcttcattat
721 gcagctgagg tctgtttttt gttgttgttg ttgtttattt tttttattcc tgcttttgag
781 gacagttggg ctatgtgtca cagctctgta gaaagaatgt gttgcctcct accttgcccc
841 caagttctga tttttaattt ctatggaaga ttttttggat tgtcggattt cctccctcac
901 atgatacccc ttatctttta taatgtctta tgcctatacc tgaatataac aacctttaaa
961 aaagcaaaat aataagaagg aaaaattcca ggagggaaaa tgaattgtct tcactcttca
1021 ttctttgaag gatttactgc aagaagtaca tgaagagcag ctggtcaacc tgctcactgt
1081 tctatctcca aatgagacac attaaagggt agcctacaaa tgttttcagg cttctttcaa
1141 agtgtaagca cttctgagct ctttagcatt gaagtgtcga aagcaactca cacgggaaga
1201 tcatttctta tttgtgctct gtgactgcca aggtgtggcc tgcactgggt tgtccaggga
1261 gacctagtgc tgtttctccc acatattcac atacgtgtct gtgtgtatat atattttttc
1321 aatttaaagg ttagtatgga atcagctgct acaagaatgc aaaaaatctt ccaaagacaa
1381 gaaaagagga aaaaaagccg ttttcatgag ctgagtgatg tagcgtaaca aacaaaatca
1441 tggagctgag gaggtgccgt gtaaacatga aggggcagat aaaggaagga gatactcatg
1501 ttgataaaga gagccctggt cctagacata gttcagccac aaagtagttg tccctttgtg
1561 gacaagtttc ccaaattccc tggactctgc ttccccatct gttaaatgag agaatagagt
1621 atggttgatt cccagcattc agtggtcctg tcaagcaacc taacaggcta gttctaattc
1681 cctattgggt agatgagggg atgacaaaga acagttttta agctatatag gaaacattgt
1741 tattggtgtt gccctatcgt gatttcagtt gaattcatgt gaaaataata gccatccttg
1801 gcctggcgcg gtggctcaca cctgtaatcc cagcactttt ggaggccaag gtgggtggat
1861 cacctgaggt caggagttca agaccagcct ggccaacatg atgaaacccc gtctctacta
1921 aaaatacaaa aaattagccg ggcatgatgg caggtgcctg taatcccagc tacttgggag
1981 gctgaagcgg aagaatcgct tgaacccaga ggtggaggtt gcagtgagcc gagatcgtgc
2041 cattgcactg taacctgggt gactgagcaa aactctgtct caaaataata ataacaatat
2101 aataataaaa aaaaaaaaaa aaaaaaaaaa
//