LOCUS BC023621 2624 bp mRNA linear HUM 23-DEC-2003
DEFINITION Homo sapiens sterol regulatory element binding transcription factor
1, mRNA (cDNA clone IMAGE:4650326), partial cds.
ACCESSION BC023621
VERSION BC023621.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2624)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2624)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC023621.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 33 Row: h Column: 24.
FEATURES Location/Qualifiers
source 1..2624
/db_xref="H-InvDB:HIT000090819"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4650326"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..2624
/gene="SREBF1"
/gene_synonym="SREBP1"
/db_xref="GeneID:6720"
/db_xref="MIM:184756"
CDS <1..2062
/gene="SREBF1"
/gene_synonym="SREBP1"
/codon_start=2
/product="SREBF1 protein"
/protein_id="AAH23621.1"
/db_xref="GeneID:6720"
/db_xref="MIM:184756"
/translation="PVFEDSKAKPEQRPSLHSRGMLDRSRLALCTLVFLCLSCNPLAS
LLGARGLPSPSDTTSVYHSPGRNVLGTESRDGPGWAQWLLPPVVWLLNGLLVLVSLVL
LFVYGEPVTRPHSGPAVYFWRHRKQADLDLARGDFAQAAQQLWLALRALGRPLPTSHL
DLACSLLWNLIRHLLQRLWVGRWLAGRAGGLQQDCALRVDASASARDAALVYHKLHQL
HTMGKHTGGHLTATNLALSALNLAECAGDAVSVATLAEIYVAAALRVKTSLPRALHFL
TRFFLSSARQACLAQSGSVPPAMQWLCHPVGHRFFVDGDWSVLSTPWESLYSLAGNPV
DPLAQVTQLFREHLLERALNCVTQPNPSPGSADGDKEFSDALGYLQLLNSCSDAAGAP
AYSFSISSSMATTTGVDPVAKWWASLTAVVIHWLRRDEEAAERLCPLVEHLPRVLQES
ERPLPRAALHSFKAARALLGCAKAESGPASLTICEKASGYLQDSLATTPASSSIDKAV
QLFLCDLLLVVRTSLWRQQQPPAPAPAAQGTSSRPQASALELRGFQRDLSSLRRLAQS
FRPAMRRVFLHEATARLMAGASPTRTHQLLDRSLRRRAGPGGKGGAVAELEPRPTRRE
HAEALLLASCYLPPGFLSAPGQRVGMLAEAARTLEKLGDRRLLHDCQQMLMRLGGGTT
VTSS"
BASE COUNT 427 a 863 c 833 g 501 t
ORIGIN
1 cccagtcttt gaggacagca aggcaaagcc agagcagcgg ccgtctctgc acagccgggg
61 catgctggac cgctcccgcc tggccctgtg cacgctcgtc ttcctctgcc tgtcctgcaa
121 ccccttggcc tccttgctgg gggcccgggg gcttcccagc ccctcagata ccaccagcgt
181 ctaccatagc cctgggcgca acgtgctggg caccgagagc agagatggcc ctggctgggc
241 ccagtggctg ctgcccccag tggtctggct gctcaatggg ctgctggtgc tcgtctcctt
301 ggtgcttctc tttgtctacg gtgagccagt cacacggccc cactcaggcc ccgccgtgta
361 cttctggagg catcgcaagc aggctgacct ggacctggcc cggggagact ttgcccaggc
421 tgcccagcag ctgtggctgg ccctgcgggc actgggccgg cccctgccca cctcccacct
481 ggacctggct tgtagcctcc tctggaacct catccgtcac ctgctgcagc gtctctgggt
541 gggccgctgg ctggcaggcc gggcaggggg cctgcagcag gactgtgctc tgcgagtgga
601 tgctagcgcc agcgcccgag acgcagccct ggtctaccat aagctgcacc agctgcacac
661 catggggaag cacacaggcg ggcacctcac tgccaccaac ctggcgctga gtgccctgaa
721 cctggcagag tgtgcagggg atgccgtgtc tgtggcgacg ctggccgaga tctatgtggc
781 ggctgcattg agagtgaaga ccagtctccc acgggccttg cattttctga cacgcttctt
841 cctgagcagt gcccgccagg cctgcctggc acagagtggc tcagtgcctc ctgccatgca
901 gtggctctgc caccccgtgg gccaccgttt cttcgtggat ggggactggt ccgtgctcag
961 taccccatgg gagagcctgt acagcttggc cgggaaccca gtggaccccc tggcccaggt
1021 gactcagcta ttccgggaac atctcttaga gcgagcactg aactgtgtga cccagcccaa
1081 ccccagccct gggtcagctg atggggacaa ggaattctcg gatgccctcg ggtacctgca
1141 gctgctgaac agctgttctg atgctgcggg ggctcctgcc tacagcttct ccatcagttc
1201 cagcatggcc accaccaccg gcgtagaccc ggtggccaag tggtgggcct ctctgacagc
1261 tgtggtgatc cactggctgc ggcgggatga ggaggcggct gagcggctgt gcccgctggt
1321 ggagcacctg ccccgggtgc tgcaggagtc tgagagaccc ctgcccaggg cagctctgca
1381 ctccttcaag gctgcccggg ccctgctggg ctgtgccaag gcagagtctg gtccagccag
1441 cctgaccatc tgtgagaagg ccagtgggta cctgcaggac agcctggcta ccacaccagc
1501 cagcagctcc attgacaagg ccgtgcagct gttcctgtgt gacctgcttc ttgtggtgcg
1561 caccagcctg tggcggcagc agcagccccc ggccccggcc ccagcagccc agggcaccag
1621 cagcaggccc caggcttccg cccttgagct gcgtggcttc caacgggacc tgagcagcct
1681 gaggcggctg gcacagagct tccggcccgc catgcggagg gtgttcctac atgaggccac
1741 ggcccggctg atggcggggg ccagccccac acggacacac cagctcctcg accgcagtct
1801 gaggcggcgg gcaggccccg gtggcaaagg aggcgcggtg gcggagctgg agccgcggcc
1861 cacgcggcgg gagcacgcgg aggccttgct gctggcctcc tgctacctgc cccccggctt
1921 cctgtcggcg cccgggcagc gcgtgggcat gctggctgag gcggcgcgca cactcgagaa
1981 gcttggcgat cgccggctgc tgcacgactg tcagcagatg ctcatgcgcc tgggcggtgg
2041 gaccactgtc acttccagct agaccccgtg tccccggcct cagcacccct gtctctagcc
2101 actttggtcc cgtgcagctt ctgtcctgcg tcgaagcttt gaaggccgaa ggcagtgcaa
2161 gagactctgg cctccacagt tcgacctgcg gctgctgtgt gccttcgcgg tggaaggccc
2221 gaggggcgcg atcttgaccc taagaccggc ggccatgatg gtgctgacct ctggtggccg
2281 atcggggcac tgcaggggcc gagccatttt ggggggcccc cctccttgct ctgcaggcac
2341 cttagtggct tttttcctcc tgtgtacagg gaagagaggg gtacatttcc ctgtgctgac
2401 ggaagccaac ttggctttcc cggactgcaa gcagggctct gccccagagg cctctctctc
2461 cgtcgtggga gagagacgtg tacatagtgt aggtcagcgt gcttagcctc ctgacctgag
2521 gctcctgtgc tactttgcct tttgcaaact ttattttcat agattgagaa gttttgtaca
2581 gagaattaaa aatgaaatta tttataaaaa aaaaaaaaaa aaaa
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