LOCUS BC023604 1026 bp mRNA linear HUM 23-DEC-2003
DEFINITION Homo sapiens Janus kinase 1 (a protein tyrosine kinase), mRNA (cDNA
clone IMAGE:4301677), partial cds.
ACCESSION BC023604
VERSION BC023604.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1026)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1026)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC023604.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 33 Row: b Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504802.
FEATURES Location/Qualifiers
source 1..1026
/db_xref="H-InvDB:HIT000090807"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4301677"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_46"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..>1026
/gene="JAK1"
/gene_synonym="JAK1A"
/db_xref="GeneID:3716"
/db_xref="MIM:147795"
CDS 6..>1026
/gene="JAK1"
/gene_synonym="JAK1A"
/codon_start=1
/product="JAK1 protein"
/protein_id="AAH23604.1"
/db_xref="GeneID:3716"
/db_xref="MIM:147795"
/translation="MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSD
REPLRLGSGEYTAEELCIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMS
LRLHYRMRFYFTNWHGTNDNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFA
QGQYDLVKCLAPIRDPKTEQDGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYK
RYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLET
LTKHYGAEIFETSMLLISSENEMNWFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSV
EKKKKK"
misc_feature 99..863
/gene="JAK1"
/gene_synonym="JAK1A"
/note="B41; Region: Band 4.1 homologues"
/db_xref="CDD:smart00295"
BASE COUNT 314 a 225 c 245 g 242 t
ORIGIN
1 aataaatgca gtatctaaat ataaaagagg actgcaatgc catggctttc tgtgctaaaa
61 tgaggagctc caagaagact gaggtgaacc tggaggcccc tgagccaggg gtggaagtga
121 tcttctatct gtcggacagg gagcccctcc ggctgggcag tggagagtac acagcagagg
181 aactgtgcat cagggctgca caggcatgcc gtatctctcc tctttgtcac aacctctttg
241 ccctgtatga cgagaacacc aagctctggt atgctccaaa tcgcaccatc accgttgatg
301 acaagatgtc cctccggctc cactaccgga tgaggttcta tttcaccaat tggcatggaa
361 ccaacgacaa tgagcagtca gtgtggcgtc attctccaaa gaagcagaaa aatggctacg
421 agaaaaaaaa gattccagat gcaacccctc tccttgatgc cagctcactg gagtatctgt
481 ttgctcaggg acagtatgat ttggtgaaat gcctggctcc tattcgagac cccaagaccg
541 agcaggatgg acatgatatt gagaacgagt gtctagggat ggctgtcctg gccatctcac
601 actatgccat gatgaagaag atgcagttgc cagaactgcc caaggacatc agctacaagc
661 gatatattcc agaaacattg aataagtcca tcagacagag gaaccttctc accaggatgc
721 ggataaataa tgttttcaag gatttcctaa aggaatttaa caacaagacc atttgtgaca
781 gcagcgtgtc cacgcatgac ctgaaggtga aatacttggc taccttggaa actttgacaa
841 aacattacgg tgctgaaata tttgagactt ccatgttact gatttcatca gaaaatgaga
901 tgaattggtt tcattcgaat gacggtggaa acgttctcta ctacgaagtg atggtgactg
961 ggaatcttgg aatccagtgg aggcataaac caaatgttgt ttctgttgaa aaaaaaaaaa
1021 aaaaaa
//