LOCUS BC023587 2659 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens REST corepressor 2, mRNA (cDNA clone MGC:23462
IMAGE:4762190), complete cds.
ACCESSION BC023587
VERSION BC023587.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2659)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2659)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC023587.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 33 Row: k Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34222235.
FEATURES Location/Qualifiers
source 1..2659
/db_xref="H-InvDB:HIT000050839"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23462 IMAGE:4762190"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_47"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2659
/gene="RCOR2"
/db_xref="GeneID:283248"
/db_xref="HGNC:HGNC:27455"
CDS 389..1960
/gene="RCOR2"
/codon_start=1
/product="REST corepressor 2"
/protein_id="AAH23587.1"
/db_xref="GeneID:283248"
/db_xref="HGNC:HGNC:27455"
/translation="MPSVMEKPSAGSGILSRSRAKTVPNGGQPHSEDDSSEEEHSHDS
MIRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGY
NIEQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQM
LPDKLIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDSDELEEGRGGVSEGEPD
PADPKREPLPSRPLNARPGPGKKEVQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSGS
PDLANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTT
DEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDG
APGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPP
PLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPP
PTLIGAPLEPPAPSL"
BASE COUNT 576 a 825 c 789 g 469 t
ORIGIN
1 gcgcccagcc gctgaacggc gtgggcaggt gggcggtggg gttccagggc gccccgagga
61 cagggggccc cgacttcagg ggaaccccaa ccctgagggg cgtacatagt aatcacgccc
121 cagccgcacc ggaccttgcg ctcatccctt gcgtccccca cttctgcaca aacttttctg
181 acgccctggc tcgtgggggt cgtggagagc gctggggcta ccaggtgggc tcccaccccg
241 ccggacccta gccacgctga cctcctgcct ctcctaacct cagtggcgac ctctccaggc
301 cgggccgggc tcggcactcg gagcgagtgc ggcaaccact gtcgctctcc gaaggctcct
361 gcgccccccg gggcagctgg gcggggtaat gccctcagtg atggagaagc cgagcgcggg
421 ctctgggatc ctgtcccgta gccgggccaa gacggtgccc aacggcggac agccccactc
481 ggaggatgac agcagcgagg aggagcactc gcacgacagc atgatccgcg ttggaaccaa
541 ttaccaggcc gtaattccgg agtgcaagcc tgagagcccc gcacgctaca gcaacaagga
601 gctgaagggg atgctggtgt ggtcacccaa ccactgtgtg tcagatgcca agcttgacaa
661 gtacattgcg atggccaagg agaagcatgg ctacaacatt gagcaggcgc tgggcatgct
721 tctgtggcat aagcacgatg tggagaagtc gctggccgac ctggccaact tcaccccatt
781 ccctgacgag tggacagtag aggacaaggt gctgtttgaa caggcctttg gcttccatgg
841 caaatgcttc cagcggatcc agcagatgct gcctgacaag ttgattccca gcctggtgaa
901 atactactac tcttggaaga agacccgcag ccgaactagt gtgatggaca gacaggcccg
961 gcggctgggg ggccgcaagg acaaagaaga cagtgatgag ctcgaagagg gtcgaggagg
1021 cgtgagtgag ggagagcccg atcctgcaga tcccaagaga gagcctctac cctctcggcc
1081 cctgaatgca cgcccaggcc ctgggaaaaa ggaggtccag gtgtctcagt accgccacca
1141 tcccttgcga acccggcgtc gcccacccaa gggcatgtac ctgagccctg agggcctcac
1201 ggcagtgtca ggaagcccgg accttgccaa cctcacgctc cgaggtcttg actctcagct
1261 catctccctc aagcgccagg tacagagcat gaagcagacg aacagcagcc tgcgccaagc
1321 cctggagggc ggtattgatc cactacgccc cccggaggcc aacaccaagt tcaactcccg
1381 ctggaccaca gatgagcagc ttttggctgt tcaagccatc cgtaggtatg gcaaagactt
1441 tggggctatt gcagaggtga ttgggaacaa gactctgacc caggtgaaga ctttctttgt
1501 gagctaccgg cgccgcttca atctggagga ggtgctgcag gaatgggagg ctgagcagga
1561 tggggcccct ggagccccag tccccatgga ggaggctagg agaggggctc cattgccagc
1621 cccagcccta gaggaagatg atgaggtcca gattacatcg gtctccacgt ccgtgccccg
1681 atcagtgccc cctgcgccac caccccctcc acctcccacc tcgctgtccc agccaccccc
1741 gctgctgagg ccacctttgc ccacggctcc cactctgctc cgacagccac ccccactgca
1801 gcagggccgc ttcctccagc cccggctggc ccccaaccag cccccaccgc ctctcatccg
1861 ccccgctctg gctgcccccc gccacagcgc ccgccctggc cctcagcccc cacccaccct
1921 gattggagcc cctctggagc ccccagcacc ctcactctga gccctgacgt cctccaccaa
1981 ccacgggctc caggacccct ttgctggcca tccccaggca tctctggtgt cactgaggac
2041 agaagggact agggctctgg cggggtcttt gtaagaccag agtttcggac agcccagccc
2101 cgccctttgg gttctgcatg tgttcctggc agctgggcct gtctcctggg gccatggccg
2161 ggctcagggg cctttgagct ggcctgaggg cactttcgct tcctggccgg tactggaatg
2221 gctgtgtcct agtctgctgg ggcttggcct ctgggtcctg ccctttgtgt gtccggggta
2281 gtgaccttag cgtggagtgg ggagagggca gttgggtgtg ctggctgttc tcattcctct
2341 ttcccttctt ttagcaataa gtctggggtg aggtggggag ggaggctgca gggggggagg
2401 tgggcagagg ggccttacag cagcagaggc tggaagagaa gctctgtctt caggggccag
2461 ctgggaaatg ctaaggagct gagggtgccc accaagccca ccttccagaa acttggagaa
2521 atgggggttg ggaacttatg cagacatgga tttatttttc aacatttttt aaaaattaaa
2581 aaaaataaaa tctaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2641 aaaaaaaaaa aaaaaaaaa
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