LOCUS BC023569 2271 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens UPF3 regulator of nonsense transcripts homolog A
(yeast), mRNA (cDNA clone MGC:20683 IMAGE:4127465), complete cds.
ACCESSION BC023569
VERSION BC023569.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2271)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2271)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 30 Row: b Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 18375523.
FEATURES Location/Qualifiers
source 1..2271
/db_xref="H-InvDB:HIT000050832"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20683 IMAGE:4127465"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2271
/gene="UPF3A"
/gene_synonym="HUPF3A"
/gene_synonym="RENT3A"
/gene_synonym="UPF3"
/db_xref="GeneID:65110"
/db_xref="HGNC:HGNC:20332"
/db_xref="MIM:605530"
CDS 21..1352
/gene="UPF3A"
/gene_synonym="HUPF3A"
/gene_synonym="RENT3A"
/gene_synonym="UPF3"
/codon_start=1
/product="UPF3 regulator of nonsense transcripts homolog A
(yeast)"
/protein_id="AAH23569.1"
/db_xref="GeneID:65110"
/db_xref="HGNC:HGNC:20332"
/db_xref="MIM:605530"
/translation="MRSEKEGAGGLRAAVAARGPSGREKLSALEVQFHRDSQQQEAET
PPTSSSGCGGGAGKPREEKRTALSKVVIRRLPPGLTKEQLEEQLRPLPAHDYFEFFAA
DLSLYPHLYSRAYINFRNPDDILLFRDRFDGYIFLDSKDPEYKKFLETYCVEEEKTSA
NPETLLGEMEAKTRELIARRTTPLLEYIKNRKLEKQRIREEKREERRRRELEKKRLRE
EEKRRRREEERCKKKETDKQKKIAEKEVRIKLLKKPEKGEEPTTEKPKERGEEIDTGG
GKQESCAPGAVVKARPMEGSLEEPQETSHSGSDKEHRDVERSQEQESEAQRYHVDDGR
RHRAHHEPERLSRRSEDEQRWGKGPGQDRGKKGSQDSGAPGEAMERLGRAQRCDDSPA
PRKERLANKDRPALQLYDPGARFRARECGGNRRICKAEGSGTGPEKREEAE"
BASE COUNT 720 a 443 c 638 g 470 t
ORIGIN
1 gagagagagg agagtgcggc atgcgctcgg aaaaggaggg ggccggaggc cttcgggcgg
61 ccgttgccgc gcggggcccg agcgggaggg agaagctgtc ggccctagaa gtgcagttcc
121 accgcgactc gcagcagcag gaggctgaga cgccgccaac ttcgtcctcc ggttgcgggg
181 gcggtgcggg caaacctcgc gaggagaaga ggacggccct gagcaaggtg gtcatccgcc
241 gcctgcctcc gggcctcacc aaggagcagc tggaggagca gctgcgcccg ctgccagcac
301 acgactactt cgagttcttc gccgccgacc tgagtcttta tcctcatctc tactcaagag
361 catacattaa ttttaggaat cctgatgaca tccttctttt tagagatcgt tttgatggat
421 atatcttcct tgacagcaaa gatccagaat ataagaagtt tttagaaacc tactgtgtgg
481 aggaagagaa gaccagtgcc aaccctgaga ctctgctggg ggagatggag gcgaagacaa
541 gagagctcat tgctagaaga accacacctc ttttggaata tattaaaaat agaaaattag
601 aaaagcagag aattcgagaa gagaagcgag aagaacggag gaggagagag ttagaaaaga
661 aacgtttgcg ggaagaggaa aaaagaagaa gaagagaaga agaaagatgc aaaaaaaaag
721 agacagataa acagaagaaa attgcagaga aagaagtaag gattaagctt cttaagaaac
781 cagaaaaggg agaggaacca accacagaga aaccaaaaga aagaggagag gagattgata
841 ctggaggtgg caagcaggaa tcctgtgccc ccggtgcagt cgtaaaagcc aggcccatgg
901 aaggctcgct ggaggagccc caggagacgt cacacagcgg cagtgataaa gagcacaggg
961 atgtggagag atctcaagaa caagaatctg aagcacaaag ataccatgtg gatgacggca
1021 ggaggcacag agctcaccac gagcctgaac ggctttccag aaggagtgag gatgagcaga
1081 gatgggggaa aggacctggc caagacagag ggaagaaggg gagccaggac agcggggctc
1141 cgggggaggc catggagaga ctgggaagag cgcagaggtg tgacgacagt ccagcaccca
1201 gaaaagagcg actggcaaac aaggaccggc cagccttgca gctgtatgat ccaggagctc
1261 gcttccgagc gcgagagtgt ggcggaaaca ggaggatctg caaggcagaa ggttcgggga
1321 ctggtcctga gaagagggaa gaggcagagt gagtcactgc acgcacctgg cctccatgga
1381 cgagcaaggg catcccagaa acgtgtaaat gaccccgagt gtgactggga aggagaactt
1441 attccttacc aggaaactgg aagctaaaaa tacagagggt gacgtagaaa cacgcagaaa
1501 ccattctaaa gaaagtagtg atcttgtatt aaattgagca gaattctcac agattttacc
1561 attcctgtta taaactagta tttgttgttt agccaaaaca gaaaatgatt tccactggac
1621 agtagaaaaa tatgtgtaaa atagggaaga aagttagtat tggatcagtg tgagtcctga
1681 agcactttca gtgctgtgag aacgacatcc actttgggtt tcattcgttt gtaagcagag
1741 gagctgtcag tcactcgtgc ttctcggtgg cctctgagcc atggtgtcga gtgaagagta
1801 gttcttgttt gttacaacct ttgtgagtca gccatgcccg caaagcgtgc tgtgttttag
1861 tcctggtagg aatatttatc agagttcaca ctatataaaa cccaacagct tcaactattg
1921 ccctttcaac agttttgcca ctgaccggat agaaacggtt tcagtctctg gatggatgtg
1981 tttgtggttt gtaaccatta cggtttaaac catggtttaa gaatttgccc aaataacaga
2041 aattttgttc gggaagggat aaactagata tagcatacag agcctgtttt tgagttttag
2101 atactttatt tgtaaataac ttaaaatagc tttctgaaac cgtgcattct gtagtttctt
2161 cctttcagtg aaattgctaa atgtcaatgt atttttggcc ctgcgatttt aaccatttat
2221 taaataaaaa ttttgttaaa gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//