LOCUS BC023553 2455 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cholinergic receptor, nicotinic, beta 1 (muscle), mRNA
(cDNA clone MGC:19706 IMAGE:3531876), complete cds.
ACCESSION BC023553
VERSION BC023553.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2455)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2455)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC023553.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 27 Row: d Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein.
FEATURES Location/Qualifiers
source 1..2455
/db_xref="H-InvDB:HIT000050824"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:19706 IMAGE:3531876"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2455
/gene="CHRNB1"
/gene_synonym="ACHRB"
/gene_synonym="CMS1D"
/gene_synonym="CMS2A"
/gene_synonym="SCCMS"
/db_xref="GeneID:1140"
/db_xref="HGNC:HGNC:1961"
/db_xref="MIM:100710"
CDS 42..1547
/gene="CHRNB1"
/gene_synonym="ACHRB"
/gene_synonym="CMS1D"
/gene_synonym="CMS2A"
/gene_synonym="SCCMS"
/codon_start=1
/product="cholinergic receptor, nicotinic, beta 1
(muscle)"
/protein_id="AAH23553.1"
/db_xref="GeneID:1140"
/db_xref="HGNC:HGNC:1961"
/db_xref="MIM:100710"
/translation="MTPGALLMLLGALGAPLAPGVRGSEAEGRLRGKLFSGYDSSVRP
AREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLR
ITAESVWLPDVVLLNNNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF
DWQNCTMVFSSYSYDSSEVSLQTGLGPDGQGHQEIHIHEGTFIENGQWEIIHKPSRLI
QPPGDPRGGREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAGEK
MGLSIFALLTLTVFLLLLADKVPETSLSVPIIIKYLMFTMVLVTFSVILSVVVLNLHH
RSPHTHQMPLWVRQIFIHKLPLYLRLKRPKPERDLMPEPPHCSSPGSGWGRGTDEYFI
RKPPSDFLFPKPNRFQPELSAPDLRRFIDGPNRAVALLPELREVVSSISYIARQLQEQ
EDHDALKEDWQFVAMVVDRLFLWTFIIFTSVGTLVIFLDATYHLPPPDPFP"
BASE COUNT 578 a 671 c 651 g 555 t
ORIGIN
1 agcggctctc tgagcgaagt cactgagcga gccgccaggc tatgacccca ggggctctgc
61 tgatgctgct gggggcgctg ggggcgccgc tcgccccagg cgtccgcggc tcggaggcgg
121 agggtcgact ccgggggaaa cttttctctg gctatgatag ctccgtgcgg ccagcgcggg
181 aggtgggaga ccgtgtcagg gtcagcgttg gtctcatcct ggcgcaactc atcagcctga
241 acgagaagga tgaagagatg agcacaaagg tgtacttaga cctggagtgg actgactaca
301 ggctgagctg ggaccctgcg gagcacgacg gcatcgattc gctccgcatc acggcggaat
361 ccgtgtggct ccctgacgtg gtgctactga acaacaatga tgggaatttt tacgtggctc
421 tggacattag cgtcgtggtg tcctccgacg gctccgtgcg ttggcaaccc ccgggcatct
481 atcgcagcag ctgcagcatc caggtcacct acttcccctt cgactggcag aattgcacta
541 tggtgttcag ctcctacagc tacgacagct cggaggtcag cctgcagaca ggcctgggtc
601 ctgacgggca agggcatcag gaaatccaca ttcatgaagg gactttcatt gagaatggcc
661 agtgggagat tatccacaag ccctctcggc taatccagcc tccaggcgat cctaggggag
721 ggagggaagg acagcgccag gaagtcatct tctacctcat catccgccgc aagcctctct
781 tctacctggt caacgtcatt gccccatgca tcctcatcac tcttctggcc atcttcgtct
841 tctacctgcc accagatgca ggagagaaga tggggctctc aatctttgcc ctgctgaccc
901 ttactgtgtt cctgctgctg ctggctgaca aagtacctga gacctcacta tcagtaccca
961 ttattatcaa gtacctcatg tttaccatgg tcctcgtcac cttctcagtc atccttagtg
1021 tcgtggttct caacctgcac caccgctcac cccacaccca ccaaatgccc ctttgggtcc
1081 gtcagatctt cattcacaaa cttccgctgt acctgcgtct aaaaaggccc aaacccgaga
1141 gagacctgat gccggagccc cctcactgtt cttctccagg aagtggctgg ggtcggggaa
1201 cagatgaata tttcatccgg aagccgccaa gtgattttct cttccccaaa cccaataggt
1261 tccagcctga actgtctgcc cctgatctgc ggcgatttat cgatggtcca aaccgggctg
1321 tggccctgct tccggagcta cgggaggtcg tctcctctat cagctacatc gctcgacagc
1381 tgcaggaaca ggaggaccac gatgcgctga aggaggactg gcagtttgtg gccatggtag
1441 tggaccgcct cttcctgtgg actttcatca tcttcaccag cgttgggacc ctagtcatct
1501 tcctggacgc cacgtaccac ttgccccctc cagacccctt tccttgaaga ctggagggtt
1561 gagacccagg ccccctgcca gttgaagtga gagtttggtg atactgtcaa gccctatcct
1621 tctctgcctc ttaactcctt cacgaggaat ctgggcctct tatttcgttt ctggggactg
1681 cattggactg agggctgggt aggcaggtgt cttggaccca cctgaaatgc agtatcatct
1741 gatttactct ttgggatctt gaagaagctc ttttgggtat caacacctag gtcgccagtg
1801 aaatagaaca cagaacagga actagattat aagccttatg aggtcaagaa atgtgacttg
1861 gccgggcgcg gtggctcacg cctgtaatcc cagcactttg ggaggccaag gcgggcggat
1921 cacctgaggt cgggagtttg agaccagccc gaccaacatg gagaaaccct gtctctacta
1981 aaaatacaaa attagccagg tgtggtggta catgcctgta atcccagcta ctagggaggc
2041 tgaggcagga gaatcactcg aacccgggag gcagaggttg cagtgagtca agatcacgcc
2101 attgcactcc agcctgggca acaagagcga aactccatct caaaaaaaaa aaaagtgtct
2161 tgttcactgc agcatgccca gtgccacgca caggtgctga cctatagtaa gtgcttaaca
2221 tttgttgaat aggggaaaga aatttccgga agtaaataca gcaattaata atgtttataa
2281 gctgggcatg gtcgctcagg ccagtaatcc cagtgactta ggaggctgag gtgggaggat
2341 tacttgaaac ccacagtttg agaccagcct gggcaacata gtgagaccct gtctctaaaa
2401 aaataaaaat agaaataaag tagtgcttat tgtttgcaaa aaaaaaaaaa aaaaa
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