LOCUS BC022458 2024 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens protein arginine methyltransferase 8, mRNA (cDNA clone
MGC:26069 IMAGE:4796524), complete cds.
ACCESSION BC022458
VERSION BC022458.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2024)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2024)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 32 Row: e Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21314691.
FEATURES Location/Qualifiers
source 1..2024
/db_xref="H-InvDB:HIT000039553"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26069 IMAGE:4796524"
/tissue_type="Brain, hypothalamus"
/clone_lib="NIH_MGC_96"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..2024
/gene="PRMT8"
/db_xref="GeneID:56341"
/db_xref="HGNC:HGNC:5188"
/db_xref="MIM:610086"
CDS 36..1220
/gene="PRMT8"
/codon_start=1
/product="protein arginine methyltransferase 8"
/protein_id="AAH22458.2"
/db_xref="GeneID:56341"
/db_xref="HGNC:HGNC:5188"
/db_xref="MIM:610086"
/translation="MGMKHSSRCLLLRRKMAENAAESTEVNSPPSQPPQPVVPAKPVQ
CVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNS
MYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSQKIIKANHLDN
IITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDR
AALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIK
EVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTH
WKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYK
MR"
BASE COUNT 512 a 505 c 525 g 482 t
ORIGIN
1 actgtctcgg tatcaccaaa cccttgcagg ctcttatggg catgaaacac tcctcccgct
61 gcctgctcct gaggaggaaa atggcggaga acgcggccga gagcaccgag gtgaacagcc
121 ccccctccca gcccccccag cccgtcgtcc ctgctaagcc cgtgcaatgc gtccatcatg
181 tgtccactca acccagctgc ccaggacggg gcaagatgtc caagctgctg aacccagagg
241 agatgacctc gagagattat tacttcgact cctatgccca ctttgggatc cacgaggaaa
301 tgctgaagga tgaggtgcgg actctcactt accggaactc catgtaccac aacaagcacg
361 tgttcaagga caaagtggta ctggatgtgg ggagtggtac tgggatcctt tccatgttcg
421 ctgccaaggc aggggccaag aaggtgtttg ggatcgaatg ctccagtatt tctgactact
481 cacagaagat cattaaggcc aaccacttgg acaacatcat caccatattt aagggtaaag
541 tggaagaggt ggagctgcct gtggagaagg tggacatcat catcagcgag tggatgggct
601 actgtctgtt ctatgagtcc atgctcaaca cggtgatctt tgccagggac aagtggctga
661 aacctggagg gcttatgttt ccagaccggg cagctttgta cgtggtagcg attgaagaca
721 gacagtacaa ggacttcaaa atccactggt gggagaatgt ctatggcttt gacatgacct
781 gcatcaggga cgtggccatg aaggagcctc tagtggacat cgtggatcca aagcaagtgg
841 tgaccaatgc ctgtttgata aaggaggtgg acatttacac agtgaagacg gaagagctat
901 cgttcacatc tgcattctgc ctgcagatac agcgcaacga ctacgtccac gccctggtca
961 cctattttaa tattgaattt accaagtgcc acaagaaaat ggggttttcc acagcccctg
1021 atgctcccta cacccactgg aagcagaccg tcttctactt ggaagattac ctcactgtcc
1081 ggagggggga ggaaatctac gggaccatat ccatgaagcc aaatgccaaa aatgtgcgag
1141 acctcgattt cacagtagac ttggatttta agggacagct gtgtgaaaca tctgtatcta
1201 atgactacaa aatgcgttag cacacgtggg aagctgcaga gagcaacgag aaaaggaact
1261 ctcacctcga tctgccgtgc cgtcccaaag aataccgttt gcaggactac acacttgaaa
1321 accagagttt tcaactctgc cttgaagatt ggtgaactcc ccagggctcc agtgggctct
1381 gccactggac agaaggcctc cagctcctcc gctctgccct ggtagccctt cacgaaggct
1441 ttgtgttgcc aacaaagagc gacctggcgt gctgtggctg ggccccgagg gtggaaacgt
1501 attcgcgtct ccccgtctcc tccttaactg tgactctccg ggtcttctga gttttgcatg
1561 ctgcgggtgt ctaggacaga ttgcttccac tagaacctgg agacatagca tctttgatag
1621 cataagccag attatctgtg tgtgcggtgg tgtgcgtgtg cgtgcatgtg tgaatgtgag
1681 cagcatagtt gatatttacc cacaaacacc tgtatatgcg tgcatataca accaagtggg
1741 tagacctagg tgttctctca gaggggtgtg tgtgtgtgtg cgtgcgcgtg tgcctagaat
1801 atatattact ctcagaggag attctgttgc ttttgaatag gaatttgttt tgtgattagt
1861 tcgccccttc cccacccctt accagatgtt aagcagctat gaaacattct ctgtactagt
1921 tctggtctcc ttttgactgg actgtggctc tgaaccttga gcatagtacc acggactccg
1981 tgggcgctca ataaacacac atgagaacaa aaaaaaaaaa aaaa
//