LOCUS BC022449 1929 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 1,
mRNA (cDNA clone MGC:25991 IMAGE:4797401), complete cds.
ACCESSION BC022449
VERSION BC022449.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1929)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1929)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 32 Row: f Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 12548775.
FEATURES Location/Qualifiers
source 1..1929
/db_xref="H-InvDB:HIT000039546"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:25991 IMAGE:4797401"
/tissue_type="Brain, hypothalamus"
/clone_lib="NIH_MGC_96"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..1929
/gene="GABRB1"
/db_xref="GeneID:2560"
/db_xref="HGNC:HGNC:4081"
/db_xref="MIM:137190"
CDS 79..1503
/gene="GABRB1"
/codon_start=1
/product="gamma-aminobutyric acid (GABA) A receptor, beta
1"
/protein_id="AAH22449.1"
/db_xref="GeneID:2560"
/db_xref="HGNC:HGNC:4081"
/db_xref="MIM:137190"
/translation="MWTVQNRESLGLLSFPVMITMVCCAHSTNEPSNMSYVKETVDRL
LKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGI
PLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA
CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKM
VSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARV
ALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGK
GPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTSVSDPKA
TMYSYDSASIQYRKPLSSREAYGRALDRHGVPSKGRNRRRASQLKVKIPDLTDVNSID
KWSRMFFPITFSLFNVVYWLYYVH"
BASE COUNT 546 a 451 c 417 g 515 t
ORIGIN
1 aattactgcc cagcagccta ctaagttgca ttccttgaat cttcgcagaa aagacaattc
61 ttttaatcag agttagtaat gtggacagta caaaatcgag agagtctggg gcttctctct
121 ttccctgtga tgattaccat ggtctgttgt gcacacagca ccaatgaacc cagcaacatg
181 tcatacgtga aagagacagt ggacagattg ctcaaaggat atgacattcg cttgcggccg
241 gacttcggag ggccccccgt cgacgttggg atgcggatcg atgtcgccag catagacatg
301 gtctccgaag tgaatatgga ttatacactc accatgtatt tccagcagtc ttggaaagac
361 aaaaggcttt cttattctgg aatcccactg aacctcaccc tagacaatag ggtagctgac
421 caactctgtg taccagacac ctactttctg aatgacaaga aatcatttgt gcatggggtc
481 acagtgaaaa atcgaatgat tcgactgcat cctgatggaa cagttctcta tggactccga
541 atcacaacca cagctgcatg tatgatggat cttcgaagat atccactgga tgagcagaac
601 tgcaccctgg agatcgaaag ttatggctat accactgatg acattgaatt ttactggaat
661 ggaggagaag gggcagtcac tggtgttaat aaaatcgaac ttcctcaatt ttcaattgtt
721 gactacaaga tggtgtctaa gaaggtggag ttcacaacag gagcgtatcc acgactgtca
781 ctaagttttc gtctaaagag aaacattggt tacttcattt tgcaaaccta catgccttct
841 acactgatta caattctgtc ctgggtgtct ttttggatca actatgatgc atctgcagcc
901 agagtcgcac taggaatcac gacggtgctt acaatgacaa ccatcagcac ccacctcagg
961 gagaccctgc caaagatccc ttatgtcaaa gcgattgata tttatctgat gggttgcttt
1021 gtgtttgtgt tcctggctct gctggagtat gcctttgtaa attacatctt ctttgggaaa
1081 ggccctcaga aaaagggagc tagcaaacaa gaccagagtg ccaatgagaa gaataaactg
1141 gagatgaata aagtccaggt cgacgcccac ggtaacattc tcctcagcac cctggaaatc
1201 cggaatgaga cgagtggctc ggaagtgctc acgagcgtga gcgaccccaa ggccaccatg
1261 tactcctatg acagcgccag catccagtac cgcaagcccc tgagcagccg cgaggcctac
1321 gggcgcgccc tggaccggca cggggtaccc agcaaggggc gcaaccgcag gcgtgcctcc
1381 cagctcaaag tcaagatccc cgacttgact gatgtgaatt ccatagacaa gtggtcccga
1441 atgtttttcc ccatcacctt ttctcttttt aatgtcgtct attggcttta ctatgtacac
1501 tgaggtctgt tctaatggtt ccatttagac tactttcctc ttctattgtt ttttaacctt
1561 acaggtcccc aacagcgata ctgctgtttc tcgaggtaag agattcagcc atccaattgg
1621 ttttaggtct tgcatatcag ttttattact gcaccatgtt tacttcaaaa agacaaaaca
1681 aaaaaaaaat tatttttcca gtctaccgtg gtccaggtta tcagctcttt aagagctcta
1741 ttaattgcca tgtttacaaa caaacacaaa gaaagaagtt agacaggtag atctttagca
1801 gtcttttcta gtttccctgg atttcactga tttatttttt agggaaaatg aaaagaggac
1861 cttgctgtcc gcctgcactg cttcctggta aactataaca aacttatgct gccaaaaaaa
1921 aaaaaaaaa
//