LOCUS BC022286 1183 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens aquaporin 4, mRNA (cDNA clone MGC:22454
IMAGE:4717755), complete cds.
ACCESSION BC022286
VERSION BC022286.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1183)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1183)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CLONTECH
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 37 Row: e Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 50659062.
FEATURES Location/Qualifiers
source 1..1183
/db_xref="H-InvDB:HIT000039449"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22454 IMAGE:4717755"
/tissue_type="Lung"
/clone_lib="NIH_MGC_77"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1183
/gene="AQP4"
/gene_synonym="HMIWC2"
/gene_synonym="MGC22454"
/gene_synonym="MIWC"
/db_xref="GeneID:361"
/db_xref="HGNC:HGNC:637"
/db_xref="MIM:600308"
CDS 21..992
/gene="AQP4"
/gene_synonym="HMIWC2"
/gene_synonym="MGC22454"
/gene_synonym="MIWC"
/codon_start=1
/product="aquaporin 4"
/protein_id="AAH22286.1"
/db_xref="GeneID:361"
/db_xref="HGNC:HGNC:637"
/db_xref="MIM:600308"
/translation="MSDRPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLA
MLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTV
AMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGL
LVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSF
GPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGS
YMEVEDNRSQVETDDLILKPGVVHVIDVDRGEEKKGKDQSGEVLSSV"
BASE COUNT 324 a 249 c 297 g 313 t
ORIGIN
1 gcactctggc tggggaaggc atgagtgaca gacccacagc aaggcggtgg ggtaagtgtg
61 gacctttgtg taccagagag aacatcatgg tggctttcaa aggggtctgg actcaagctt
121 tctggaaagc agtcacagcg gaatttctgg ccatgcttat ttttgttctc ctcagcctgg
181 gatccaccat caactggggt ggaacagaaa agcctttacc ggtcgacatg gttctcatct
241 ccctttgctt tggactcagc attgcaacca tggtgcagtg ctttggccat atcagcggtg
301 gccacatcaa ccctgcagtg actgtggcca tggtgtgcac caggaagatc agcatcgcca
361 agtctgtctt ctacatcgca gcccagtgcc tgggggccat cattggagca ggaatcctct
421 atctggtcac acctcccagt gtggtgggag gcctgggagt caccatggtt catggaaatc
481 ttaccgctgg tcatggtctc ctggttgagt tgataatcac atttcaattg gtgtttacta
541 tctttgccag ctgtgattcc aaacggactg atgtcactgg ctcaatagct ttagcaattg
601 gattttctgt tgcaattgga catttatttg caatcaatta tactggtgcc agcatgaatc
661 ccgcccgatc ctttggacct gcagttatca tgggaaattg ggaaaaccat tggatatatt
721 gggttgggcc catcatagga gctgtcctcg ctggtggcct ttatgagtat gtcttctgtc
781 cagatgttga attcaaacgt cgttttaaag aagccttcag caaagctgcc cagcaaacaa
841 aaggaagcta catggaggtg gaggacaaca ggagtcaggt agagacggat gacctgattc
901 taaaacctgg agtggtgcat gtgattgacg ttgaccgggg agaggagaag aaggggaaag
961 accaatctgg agaggtattg tcttcagtat gactagaaga tcgcactgaa agcagacaag
1021 actccttaga actgtcctca gatttccttc cacccattaa ggaaacagat ttgttataaa
1081 ttagaaatgt gcaggtttgt tgtttcatgt catattactc agtctaaaca ataaatattt
1141 cataatttac aaagtaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//