LOCUS BC022071 866 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens glutathione peroxidase 4 (phospholipid
hydroperoxidase), mRNA (cDNA clone MGC:33153 IMAGE:4821595),
complete cds.
ACCESSION BC022071
VERSION BC022071.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 866)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 866)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (22-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 46 Row: i Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504106.
FEATURES Location/Qualifiers
source 1..866
/db_xref="H-InvDB:HIT000090523"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:33153 IMAGE:4821595"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..866
/gene="GPX4"
/gene_synonym="MCSP"
/gene_synonym="PHGPx"
/gene_synonym="snGPx"
/gene_synonym="snPHGPx"
/db_xref="GeneID:2879"
/db_xref="HGNC:HGNC:4556"
/db_xref="MIM:138322"
CDS 56..649
/gene="GPX4"
/gene_synonym="MCSP"
/gene_synonym="PHGPx"
/gene_synonym="snGPx"
/gene_synonym="snPHGPx"
/codon_start=1
/transl_except=(pos:272..274,aa:OTHER)
/product="glutathione peroxidase 4 (phospholipid
hydroperoxidase)"
/protein_id="AAH22071.1"
/db_xref="GeneID:2879"
/db_xref="HGNC:HGNC:4556"
/db_xref="MIM:138322"
/translation="MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEF
SAKDIDGHMVNLDKYRGFVCIVTNVASQXGKTEVNYTQLVDLHARYAECGLRILAFPC
NQFGKQEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNA
IKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDLPHYF"
BASE COUNT 184 a 271 c 263 g 148 t
ORIGIN
1 agcggattgg tcggctggac gaggggagga gccgctggct cccagccccg ccgcgatgag
61 cctcggccgc ctttgccgcc tactgaagcc ggcgctgctc tgtggggctc tggccgcgcc
121 tggcctggcc gggaccatgt gcgcgtcccg ggacgactgg cgctgtgcgc gctccatgca
181 cgagttttcc gccaaggaca tcgacgggca catggttaac ctggacaagt accggggctt
241 cgtgtgcatc gtcaccaacg tggcctccca gtgaggcaag accgaagtaa actacactca
301 gctcgtcgac ctgcacgccc gatacgctga gtgtggtttg cggatcctgg ccttcccgtg
361 taaccagttc gggaagcagg agccagggag taacgaagag atcaaagagt tcgccgcggg
421 ctacaacgtc aaattcgata tgttcagcaa gatctgcgtg aacggggacg acgcccaccc
481 gctgtggaag tggatgaaga tccaacccaa gggcaagggc atcctgggaa atgccatcaa
541 gtggaacttc accaagttcc tcatcgacaa gaacggctgc gtggtgaagc gctacggacc
601 catggaggag cccctggtga tagagaagga cctgccccac tatttctagc tccacaagtg
661 tgtggccccg cccgagcccc tgcccacgcc cttggagcct tccaccggca ctcatgacgg
721 cctgcctgca aacctgctgg tggggcagac ccgaaaatcc agcgtgcacc ccgccggagg
781 aaggtcccat ggcctgctgg gcttggctcg gcgcccccac ccctggctac cttgtgggaa
841 taattctccg aaaaaaaaaa aaaaaa
//