LOCUS BC021567 876 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens glutathione peroxidase 4 (phospholipid
hydroperoxidase), mRNA (cDNA clone MGC:31923 IMAGE:4581069),
complete cds.
ACCESSION BC021567
VERSION BC021567.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 876)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 876)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 40 Row: e Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504106.
FEATURES Location/Qualifiers
source 1..876
/db_xref="H-InvDB:HIT000090423"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:31923 IMAGE:4581069"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..876
/gene="GPX4"
/gene_synonym="MCSP"
/gene_synonym="PHGPx"
/gene_synonym="snGPx"
/gene_synonym="snPHGPx"
/db_xref="GeneID:2879"
/db_xref="HGNC:HGNC:4556"
/db_xref="MIM:138322"
CDS 33..626
/gene="GPX4"
/gene_synonym="MCSP"
/gene_synonym="PHGPx"
/gene_synonym="snGPx"
/gene_synonym="snPHGPx"
/codon_start=1
/transl_except=(pos:249..251,aa:OTHER)
/product="glutathione peroxidase 4 (phospholipid
hydroperoxidase)"
/protein_id="AAH21567.1"
/db_xref="GeneID:2879"
/db_xref="HGNC:HGNC:4556"
/db_xref="MIM:138322"
/translation="MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEF
SAKDIDGHMVNLDKYRGFVCIVTNVASQXGKTEVNYTQLVDLHARYAECGLRILAFPC
NQFGKQEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNA
IKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDLPHYF"
BASE COUNT 214 a 266 c 253 g 143 t
ORIGIN
1 gggaggagcc gctggctccc agccccgccg cgatgagcct cggccgcctt tgccgcctac
61 tgaagccggc gctgctctgt ggggctctgg ccgcgcctgg cctggccggg accatgtgcg
121 cgtcccggga cgactggcgc tgtgcgcgct ccatgcacga gttttccgcc aaggacatcg
181 acgggcacat ggttaacctg gacaagtacc ggggcttcgt gtgcatcgtc accaacgtgg
241 cctcccagtg aggcaagacc gaagtaaact acactcagct cgtcgacctg cacgcccgat
301 acgctgagtg tggtttgcgg atcctggcct tcccgtgtaa ccagttcggg aagcaggagc
361 cagggagtaa cgaagagatc aaagagttcg ccgcgggcta caacgtcaaa ttcgatatgt
421 tcagcaagat ctgcgtgaac ggggacgacg cccacccgct gtggaagtgg atgaagatcc
481 aacccaaggg caagggcatc ctgggaaatg ccatcaagtg gaacttcacc aagttcctca
541 tcgacaagaa cggctgcgtg gtgaagcgct acggacccat ggaggagccc ctggtgatag
601 agaaggacct gccccactat ttctagctcc acaagtgtgt ggccccgccc gagcccctgc
661 ccacgccctt ggagccttcc accggcactc atgacggcct gcctgcaaac ctgctggtgg
721 ggcagacccg aaaatccagc gtgcaccccg ccggaggaag gtcccatggc ctgctgggct
781 tggctcggcg cccccacccc tggctacctt gtgggaataa acagacaaat tagaaaaaaa
841 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//