LOCUS BC021289 2544 bp mRNA linear HUM 19-MAR-2007
DEFINITION Homo sapiens alkaline phosphatase, liver/bone/kidney, mRNA (cDNA
clone MGC:29601 IMAGE:5087597), complete cds.
ACCESSION BC021289
VERSION BC021289.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2544)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2544)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC021289.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 39 Row: o Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13787192.
FEATURES Location/Qualifiers
source 1..2544
/db_xref="H-InvDB:HIT000039191"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:29601 IMAGE:5087597"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_99"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene 1..2544
/gene="ALPL"
/gene_synonym="AP-TNAP"
/gene_synonym="TNAP"
/gene_synonym="TNSALP"
/db_xref="GeneID:249"
/db_xref="HGNC:HGNC:438"
/db_xref="MIM:171760"
CDS 189..1763
/gene="ALPL"
/gene_synonym="AP-TNAP"
/gene_synonym="TNAP"
/gene_synonym="TNSALP"
/codon_start=1
/product="alkaline phosphatase, liver/bone/kidney"
/protein_id="AAH21289.3"
/db_xref="GeneID:249"
/db_xref="HGNC:HGNC:438"
/db_xref="MIM:171760"
/translation="MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQ
KLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYN
TNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKS
VGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVI
MGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELL
TLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGG
RIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRG
NSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLR
HETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAA
GPLLLALALYPLSVLF"
BASE COUNT 574 a 830 c 668 g 472 t
ORIGIN
1 ctcccgccac tccgcgcccg ctatcctggc tccgtgctcc cacgcgcttg tgcctggacg
61 gaccctcgcc agtgctctgc gcaggattgg aacatcagtt aacatctgac cactgccagc
121 ccaccccctc ccacccacgt cgattgcatc tctgggctcc agggataaag caggtcttgg
181 ggtgcaccat gatttcacca ttcttagtac tggccattgg cacctgcctt actaactcct
241 tagtgccaga gaaagagaaa gaccccaagt actggcgaga ccaagcgcaa gagacactga
301 aatatgccct ggagcttcag aagctcaaca ccaacgtggc taagaatgtc atcatgttcc
361 tgggagatgg gatgggtgtc tccacagtga cggctgcccg catcctcaag ggtcagctcc
421 accacaaccc tggggaggag accaggctgg agatggacaa gttccccttc gtggccctct
481 ccaagacgta caacaccaat gcccaggtcc ctgacagcgc cggcaccgcc accgcctacc
541 tgtgtggggt gaaggccaat gagggcaccg tgggggtaag cgcagccact gagcgttccc
601 ggtgcaacac cacccagggg aacgaggtca cctccatcct gcgctgggcc aaggacgctg
661 ggaaatctgt gggcattgtg accaccacga gagtgaacca tgccaccccc agcgccgcct
721 acgcccactc ggctgaccgg gactggtact cagacaacga gatgccccct gaggccttga
781 gccagggctg taaggacatc gcctaccagc tcatgcataa catcagggac attgacgtga
841 tcatgggggg tggccggaaa tacatgtacc ccaagaataa aactgatgtg gagtatgaga
901 gtgacgagaa agccaggggc acgaggctgg acggcctgga cctcgttgac acctggaaga
961 gcttcaaacc gagatacaag cactcccact tcatctggaa ccgcacggaa ctcctgaccc
1021 ttgaccccca caatgtggac tacctattgg gtctcttcga gccaggggac atgcagtacg
1081 agctgaacag gaacaacgtg acggacccgt cactctccga gatggtggtg gtggccatcc
1141 agatcctgcg gaagaacccc aaaggcttct tcttgctggt ggaaggaggc agaattgacc
1201 acgggcacca tgaaggaaaa gccaagcagg ccctgcatga ggcggtggag atggaccggg
1261 ccatcgggca ggcaggcagc ttgacctcct cggaagacac tctgaccgtg gtcactgcgg
1321 accattccca cgtcttcaca tttggtggat acaccccccg tggcaactct atctttggtc
1381 tggcccccat gctgagtgac acagacaaga agcccttcac tgccatcctg tatggcaatg
1441 ggcctggcta caaggtggtg ggcggtgaac gagagaatgt ctccatggtg gactatgctc
1501 acaacaacta ccaggcgcag tctgctgtgc ccctgcgcca cgagacccac ggcggggagg
1561 acgtggccgt cttctccaag ggccccatgg cgcacctgct gcacggcgtc cacgagcaga
1621 actacgtccc ccacgtgatg gcgtatgcag cctgcatcgg ggccaacctc ggccactgtg
1681 ctcctgccag ctcggcaggc agccttgctg caggccccct gctgctcgcg ctggccctct
1741 accccctgag cgtcctgttc tgagggccca gggcccgggc acccacaagc ccgtgacaga
1801 tgccaacttc ccacacggca gcccccccct caaggggcag ggaggtgggg gcctcctcag
1861 cctctgcaac tgcaagaaag gggacccagg aaaccaaagt ctgccgccca cctcgctccc
1921 ctctggaatc ttccccaagg gccaaaccca cttctggcct ccagcctttg ctccctcccc
1981 gctgcccttt ggccaacagg gtagatttct cttgggcagg cagagagtac agactgcaga
2041 cattctcaaa gcctcttatt tttctagcga acgtatttct ccagacccag aggccctgaa
2101 gcctccgtgg aacattctgg atctgaccct cccagtctca tctcctgacc ctcccactcc
2161 catctcctta cctctggaac cccccaggcc ctacaatgct catgtccctg tccccaggcc
2221 cagccctcct tcaggggagt tgaggtcttt ctcctcagga caaggccttg ctcactcact
2281 cactccaaga ccaccagggt cccaggaagc cggtgcctgg gtggccatcc tacccagcgt
2341 ggcccaggcc gggaagagcc acctggcagg gctcacactc ctgggctctg aacacacacg
2401 ccagctcctc tctgaagcga ctctcctgtt tggaacggca aaaaaaaatt tttttttctc
2461 tttttggtgg tggttaaaag ggaacacaaa acatttaaat aaaactttcc aaatatttcc
2521 gaggacaaaa aaaaaaaaaa aaaa
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