LOCUS BC021281 2547 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens ATP-binding cassette, sub-family G (WHITE), member 2,
mRNA (cDNA clone MGC:29446 IMAGE:4908836), complete cds.
ACCESSION BC021281
VERSION BC021281.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2547)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2547)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC021281.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 39 Row: k Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 62526032.
FEATURES Location/Qualifiers
source 1..2547
/db_xref="H-InvDB:HIT000039186"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:29446 IMAGE:4908836"
/tissue_type="Pancreas, epithelioid carcinoma"
/clone_lib="NIH_MGC_42"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2547
/gene="ABCG2"
/gene_synonym="ABC15"
/gene_synonym="ABCP"
/gene_synonym="BCRP"
/gene_synonym="BCRP1"
/gene_synonym="BMDP"
/gene_synonym="CDw338"
/gene_synonym="EST157481"
/gene_synonym="MRX"
/gene_synonym="MXR"
/gene_synonym="MXR1"
/db_xref="GeneID:9429"
/db_xref="HGNC:HGNC:74"
/db_xref="MIM:603756"
CDS 494..2461
/gene="ABCG2"
/gene_synonym="ABC15"
/gene_synonym="ABCP"
/gene_synonym="BCRP"
/gene_synonym="BCRP1"
/gene_synonym="BMDP"
/gene_synonym="CDw338"
/gene_synonym="EST157481"
/gene_synonym="MRX"
/gene_synonym="MXR"
/gene_synonym="MXR1"
/codon_start=1
/product="ATP-binding cassette, sub-family G (WHITE),
member 2"
/protein_id="AAH21281.1"
/db_xref="GeneID:9429"
/db_xref="HGNC:HGNC:74"
/db_xref="MIM:603756"
/translation="MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICY
RVKLKSGFLPCRKPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGL
SGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNER
INRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDS
STANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGY
FESAGYHCEAYNNPADFFLDIINGDSTAVALNREEDFKATEIIEPSKQDKPLIEKLAE
IYVNSSFYKETKAELHQLSGGEKKKKITVFKEISYTTSFCHQLRWVSKRSFKNLLGNP
QASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVV
EKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFV
MMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLS
WLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPW
GLWKNHVALACMIVIFLTIAYLKLLFLKKYS"
BASE COUNT 690 a 569 c 598 g 690 t
ORIGIN
1 gtcagcgctg cctgagctcg tcccctggat gtccgggtct ccccaggcgg ccacccgccg
61 gctcccatcg tgacctccag ccgcagcgcc tcccacgccg gccgccgcgc gaggggagcg
121 ctcgggcgcg ccgggtgtgg ttgggggaag gggttgtgcc gcgcgcgggc tgcgtgctgt
181 gcccactcaa aaggttccgg gcgcgcagga gggaagaggc agtgcccgcc actcccactg
241 agattgagag acgcggcaag gaggcagcct gtggaggaac tgggtaggat ttaggaatgc
301 accgtgcaca tgcttggtgg tcttgttaag tggaaactgc tgctttagag tttgtttgga
361 aggtccgggt gactcatccc aacatttaca tccttaattg ttaaagcgct gcctccgagc
421 gcacgcatcc tgagatcctg agcctttggt taagaccgag ctctattaag ctgaaaagat
481 aaaaactctc cagatgtctt ccagtaatgt cgaagttttt atcccagtgt cacaaggaaa
541 caccaatggc ttccccgcga cagcttccaa tgacctgaag gcatttactg aaggagctgt
601 gttaagtttt cataacatct gctatcgagt aaaactgaag agtggctttc taccttgtcg
661 aaaaccagtt gagaaagaaa tattatcgaa tatcaatggg atcatgaaac ctggtctcaa
721 cgccatcctg ggacccacag gtggaggcaa atcttcgtta ttagatgtct tagctgcaag
781 gaaagatcca agtggattat ctggagatgt tctgataaat ggagcaccgc gacctgccaa
841 tttcaaatgt aattcaggtt acgtggtaca agatgatgtt gtgatgggca ctctgacggt
901 gagagaaaac ttacagttct cagcagctct tcggcttgca acaactatga cgaatcatga
961 aaaaaacgaa cggattaaca gggtcattca agagttaggt ctggataaag tggcagactc
1021 caaggttgga actcagttta tccgtggtgt gtctggagga gaaagaaaaa ggactagtat
1081 aggaatggag cttatcactg atccttccat cttgttcttg gatgagccta caactggctt
1141 agactcaagc acagcaaatg ctgtcctttt gctcctgaaa aggatgtcta agcagggacg
1201 aacaatcatc ttctccattc atcagcctcg atattccatc ttcaagttgt ttgatagcct
1261 caccttattg gcctcaggaa gacttatgtt ccacgggcct gctcaggagg ccttgggata
1321 ctttgaatca gctggttatc actgtgaggc ctataataac cctgcagact tcttcttgga
1381 catcattaat ggagattcca ctgctgtggc attaaacaga gaagaagact ttaaagccac
1441 agagatcata gagccttcca agcaggataa gccactcata gaaaaattag cggagattta
1501 tgtcaactcc tccttctaca aagagacaaa agctgaatta catcaacttt ccgggggtga
1561 gaagaagaag aagatcacag tcttcaagga gatcagctac accacctcct tctgtcatca
1621 actcagatgg gtttccaagc gttcattcaa aaacttgctg ggtaatcccc aggcctctat
1681 agctcagatc attgtcacag tcgtactggg actggttata ggtgccattt actttgggct
1741 aaaaaatgat tctactggaa tccagaacag agctggggtt ctcttcttcc tgacgaccaa
1801 ccagtgtttc agcagtgttt cagccgtgga actctttgtg gtagagaaga agctcttcat
1861 acatgaatac atcagcggat actacagagt gtcatcttat ttccttggaa aactgttatc
1921 tgatttatta cccatgagga tgttaccaag tattatattt acctgtatag tgtacttcat
1981 gttaggattg aagccaaagg cagatgcctt cttcgttatg atgtttaccc ttatgatggt
2041 ggcttattca gccagttcca tggcactggc catagcagca ggtcagagtg tggtttctgt
2101 agcaacactt ctcatgacca tctgttttgt gtttatgatg attttttcag gtctgttggt
2161 caatctcaca accattgcat cttggctgtc atggcttcag tacttcagca ttccacgata
2221 tggatttacg gctttgcagc ataatgaatt tttgggacaa aacttctgcc caggactcaa
2281 tgcaacagga aacaatcctt gtaactatgc aacatgtact ggcgaagaat atttggtaaa
2341 gcagggcatc gatctctcac cctggggctt gtggaagaat cacgtggcct tggcttgtat
2401 gattgttatt ttcctcacaa ttgcctacct gaaattgtta tttcttaaaa aatattctta
2461 aatttcccct taattcagta tgatttatcc tcacataaaa aagaagcact ttgattgaag
2521 tattcaaaaa aaaaaaaaaa aaaaaaa
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