LOCUS BC021267 1471 bp mRNA linear HUM 18-MAY-2004 DEFINITION Homo sapiens kelch-like 14 (Drosophila), mRNA (cDNA clone MGC:29780 IMAGE:4588702), complete cds. ACCESSION BC021267 VERSION BC021267.2 KEYWORDS MGC. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 1471) AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A. TITLE Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002) PUBMED 12477932 REFERENCE 2 (bases 1 to 1471) AUTHORS Strausberg,R. TITLE Direct Submission JOURNAL Submitted (14-JAN-2002) National Institutes of Health, Mammalian Gene Collection (MGC), Cancer Genomics Office, National Cancer Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590, USA REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov COMMENT On Aug 19, 2003 this sequence version replaced BC021267.1. Contact: MGC help desk Email: cgapbs-r@mail.nih.gov Tissue Procurement: DCTD/DTP cDNA Library Preparation: Rubin Laboratory cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) DNA Sequencing by: National Institutes of Health Intramural Sequencing Center (NISC), Gaithersburg, Maryland; Web site: http://www.nisc.nih.gov/ Contact: nisc_mgc@nhgri.nih.gov Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B., Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S., Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P., Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R., Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C., McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W., Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L., Young,A., Zhang,L.-H. and Green,E.D. Clone distribution: MGC clone distribution information can be found through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov Series: IRAL Plate: 39 Row: e Column: 15 This clone was selected for full length sequencing because it passed the following selection criteria: Hexamer frequency ORF analysis. FEATURES Location/Qualifiers source 1..1471 /db_xref="H-InvDB:HIT000039180" /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /clone="MGC:29780 IMAGE:4588702" /tissue_type="Kidney, renal cell adenocarcinoma" /clone_lib="NIH_MGC_14" /lab_host="DH10B-R" /note="Vector: pOTB7" gene 1..1471 /gene="KLHL14" /gene_synonym="KIAA1384" /db_xref="GeneID:57565" CDS 257..1423 /gene="KLHL14" /gene_synonym="KIAA1384" /codon_start=1 /product="KLHL14 protein" /protein_id="AAH21267.1" /db_xref="GeneID:57565" /translation="MSRSGDRTSTFDPSHSDNLLHGLNLLWRKQLFCDVTLTAQGQQF HCHKAVLASCSQYFRSLFSSHPPLGGGVGGQDGLGAPKDQQQPPQQQPSQQQQPPPQE EPGTPSSSPDDKLLTSPRAINNLVLQGCSSIGLRLVLEYLYTANVTLSLDTVEEVLSV SKILHIPQVTKLCVQFLNDQISVQNYKQVCKIAALHGLEETKKLANKYLVEDVLLLNF EEMRALLDSLPPPVESELALFQMSVLWLEHDRETRMQYAPDLMKRLRFALIPAPELVE RVQSVDFMRTDPVCQKLLLDAMNYHLMPFRQHCRQSLASRIRSNKKMLLLVGGLPPGP DRLPSNLVQYYDDEKKTWKILTITGPHPISGKQESASSPEFRRRKTREFSNNTM" BASE COUNT 350 a 443 c 404 g 274 t ORIGIN 1 cttttctccc tctcctacat tttcttgctg ttgctaattc atggtgatca aatgatgtac 61 gacaaaataa attgtaaaga gtgactgcct ggagttggga accagaaggt gttttccccc 121 tcccaaggag acagcaaacc tttaaaaagg aaggacaatt gatttttggg gggagcttaa 181 gtgagccttg actttgcagc tggttgagaa caggttggag gagggtttaa agccaggtgc 241 accgagtcag ctcgccatgt ccagatccgg ggacaggacc tccaccttcg accccagcca 301 cagcgacaac ctgctgcacg gcctcaacct gctgtggagg aagcagctgt tttgcgacgt 361 gaccctgacg gcccagggcc agcagttcca ttgccacaag gccgtgctgg cctcctgctc 421 gcagtacttc cgatcgctct tctccagcca cccccctctc gggggagggg tcggcggcca 481 ggacggcctg ggggccccca aggaccagca gcagccgccg cagcagcagc cgtcacagca 541 gcagcagccg ccgccgcagg aggagcccgg gactccttct tcctcccccg acgacaagct 601 gctgaccagc ccccgggcca tcaacaacct ggtgctgcag ggctgctcgt ccatcgggct 661 gcgcctggtg ctcgagtacc tctacacggc caacgtgacc ctgtccctgg acacggtgga 721 ggaggtgctg tcggtcagca agatcctgca catcccccag gtcaccaagc tctgcgtgca 781 gttcctcaac gaccagatct cggtgcagaa ctacaagcag gtgtgcaaga tcgccgcgct 841 gcacggcctg gaggagacca agaagctggc caacaagtac ctggtggagg atgtgctgct 901 gctcaacttc gaggagatgc gcgccctgct ggactcgctg ccgccccccg tggagtcgga 961 gctggcgctc ttccagatgt ccgtgctgtg gctggagcac gaccgcgaga cccgcatgca 1021 gtatgcgcct gacctcatga agcgcctccg cttcgccctc atcccggccc cggagctggt 1081 ggagcgggtc cagtcagtgg atttcatgcg aaccgaccca gtctgccaga agctgctgct 1141 ggacgccatg aactaccacc tgatgccctt caggcagcac tgcaggcaga gcctggccag 1201 cagaattcgc tctaacaaga aaatgctgtt attggttgga gggctgcctc ctggaccgga 1261 ccggctcccc agcaatttgg ttcagtatta cgacgatgaa aagaagacat ggaaaatact 1321 cacaatcaca ggaccacacc ccatttcagg gaagcaggaa agtgcaagct caccagagtt 1381 cagaaggagg aaaaccagag aattttcaaa caacacaatg tgactatcat aattatacta 1441 ctagacatca aaaaaaaaaa aaaaaaaaaa a //