LOCUS BC021224 3300 bp mRNA linear HUM 11-SEP-2007
DEFINITION Homo sapiens forkhead box O3, mRNA (cDNA clone MGC:12739
IMAGE:4137370), complete cds.
ACCESSION BC021224
VERSION BC021224.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3300)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3300)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC021224.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 17 Row: j Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 42519915.
FEATURES Location/Qualifiers
source 1..3300
/db_xref="H-InvDB:HIT000039154"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12739 IMAGE:4137370"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3300
/gene="FOXO3"
/gene_synonym="AF6q21"
/gene_synonym="FKHRL1P2"
/gene_synonym="FOXO2"
/db_xref="GeneID:2309"
/db_xref="HGNC:HGNC:3821"
/db_xref="MIM:602681"
CDS 305..2326
/gene="FOXO3"
/gene_synonym="AF6q21"
/gene_synonym="FKHRL1P2"
/gene_synonym="FOXO2"
/codon_start=1
/product="forkhead box O3"
/protein_id="AAH21224.1"
/db_xref="GeneID:2309"
/db_xref="HGNC:HGNC:3821"
/db_xref="MIM:602681"
/translation="MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASP
AKPSGETAADSMIPEEEDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLA
PGGQDPGSGPATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNL
SYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHS
RFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQT
APESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELD
EVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLD
NITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQT
IQENKPATFSSMSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNSRRN
VMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLG
SAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFNGSLECDM
ESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG"
BASE COUNT 736 a 978 c 927 g 659 t
ORIGIN
1 gggaggagga ggaatgtgga aggtggcggc gcgcgagctg acaggcggtt cctcgggcgg
61 gctgcggcga cggcccgagc gcttctcctt cgccgaggtt gcgcgccccc tcctcgccgt
121 gccccgggcc cgcgcgggat cgtgcgtcgt cccgccgcgt ccctgaaggg aaggaagcga
181 ggcggcggcg gcggcgcccg ggagccggag ccttcgcggc gtccacgtcc ctcccccgct
241 gcaccccgcc ccggcgcgag aggagagcgc gagagcccca gccgcgggcg ggcgggcggc
301 gaagatggca gaggcaccgg cttccccggc cccgctctct ccgctcgaag tggagctgga
361 cccggagttc gagccccaga gccgtccgcg atcctgtacg tggcccctgc aaaggccgga
421 gctccaagcg agccctgcca agccctcggg ggagacggcc gccgactcca tgatccccga
481 ggaggaggac gatgaagacg acgaggacgg cgggggacgg gccggctcgg ccatggcgat
541 cggcggcggc ggcgggagcg gcacgctggg ctccgggctg ctccttgagg actcggcccg
601 ggtgctggca cccggagggc aagaccccgg gtctgggcca gccaccgcgg cgggcgggct
661 gagcgggggt acacaggcgc tgctgcagcc tcagcaaccg ctgccaccgc cgcagccggg
721 ggcggctggg ggctccgggc agccgaggaa atgttcgtcg cggcggaacg cctggggaaa
781 cctgtcctac gcggacctga tcacccgcgc catcgagagc tccccggaca aacggctcac
841 tctgtcccag atctacgagt ggatggtgcg ttgcgtgccc tacttcaagg ataagggcga
901 cagcaacagc tctgccggct ggaagaactc catccggcac aacctgtcac tgcatagtcg
961 attcatgcgg gtccagaatg agggaactgg caagagctct tggtggatca tcaaccctga
1021 tggggggaag agcggaaaag ccccccggcg gcgggctgtc tccatggaca atagcaacaa
1081 gtataccaag agccgtggcc gcgcagccaa gaagaaggca gccctgcaga cagcccccga
1141 atcagctgac gacagtccct cccagctctc caagtggcct ggcagcccca cgtcacgcag
1201 cagtgatgag ctggatgcgt ggacggactt ccgttcacgc accaattcta acgccagcac
1261 agtcagtggc cgcctgtcgc ccatcatggc aagcacagag ttggatgaag tccaggacga
1321 tgatgcgcct ctctcgccca tgctctacag cagctcagcc agcctgtcac cttcagtaag
1381 caagccgtgc acggtggaac tgccacggct gactgatatg gcaggcacca tgaatctgaa
1441 tgatgggctg actgaaaacc tcatggacga cctgctggat aacatcacgc tcccgccatc
1501 ccagccatcg cccactgggg gactcatgca gcggagctct agcttcccgt ataccaccaa
1561 gggctcgggc ctgggctccc caaccagctc ctttaacagc acggtgttcg gaccttcatc
1621 tctgaactcc ctacgccagt ctcccatgca gaccatccaa gagaacaagc cagctacctt
1681 ctcttccatg tcacactatg gtaaccagac actccaggac ctgctcactt cggactcact
1741 tagccacagc gatgtcatga tgacacagtc ggaccccttg atgtctcagg ccagcaccgc
1801 tgtgtctgcc cagaattccc gccggaacgt gatgcttcgc aatgatccga tgatgtcctt
1861 tgctgcccag cctaaccagg gaagtttggt caatcagaac ttgctccacc accagcacca
1921 aacccagggc gctcttggtg gcagccgtgc cttgtcgaat tctgtcagca acatgggctt
1981 gagtgagtcc agcagccttg ggtcagccaa acaccagcag cagtctcctg tcagccagtc
2041 tatgcaaacc ctctcggact ctctctcagg ctcctccttg tactcaacta gtgcaaacct
2101 gcccgtcatg ggccatgaga agttccccag cgacttggac ctggacatgt tcaatgggag
2161 cttggaatgt gacatggagt ccattatccg tagtgaactc atggatgctg atgggttgga
2221 ttttaacttt gattccctca tctccacaca gaatgttgtt ggtttgaacg tggggaactt
2281 cactggtgct aagcaggcct catctcagag ctgggtgcca ggctgaagga tcactgagga
2341 aggggaagtg ggcaaagcag accctcaaac tgacacaaga cctacagaga aaaccctttg
2401 ccaaatctgc tctcagcaag tggacagtga taccgtttac agcttaacac ctttgtgaat
2461 cccacgccat tttcctaacc cagcagagac tgttaatggc cccttaccct gggtgaagca
2521 cttacccttg gaacagaact ctaaaaagta tgcaaaatct tccttgtaca gggtggtgag
2581 ccgcctgcca gtggaggaca gcacccctca gcaccaccca ccctcattca gagcacaccg
2641 tgagcccccg tcggccattc tgtggtgttt taatattgcg atggtttatg ggacgtttta
2701 agtgttgttc ttgtgtttgt tttcctttga ctttctgagt ttttcacatg cattaacttg
2761 cggtattttt ctgttaaaat gttaaccgtc cttcccctag caaatttaaa aacagaaaga
2821 aaatgttgta ccagttacca ttccgggttc gagcatcaca agcttttgag cgcatggaac
2881 tccataaact aacaaattac ataaactaaa gggggatttt ctttcttctt ttgtttggta
2941 gaaaattatc cttttctaaa aactgaacaa tggcacaatt gtttgctatg tgcacccgtc
3001 caggacagaa ccgtgcatag gcaaaaggag tggagcacag cgtccggccc agtgtgtttc
3061 cggttctgag tcagggtgat ctgtggacgg gaccccagca ccaagtctac gggtgccaga
3121 tcagtagggc ctgtgatttc ctgtcagtgt cctcagctaa tgtgaacagt gttggtctgc
3181 tggttagaaa ctagaatatt gatattttca ggaaagaaat cagctcagct ctccactcat
3241 tgccaaatgt cactaaaggg tttagtttta aggagaaaga aaaaaaaaaa aaaaaaaaaa
//