LOCUS BC021208 3859 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens leucine zipper-EF-hand containing transmembrane
protein 1, mRNA (cDNA clone MGC:12631 IMAGE:4126510), complete cds.
ACCESSION BC021208
VERSION BC021208.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3859)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3859)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 17 Row: h Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 6912481.
FEATURES Location/Qualifiers
source 1..3859
/db_xref="H-InvDB:HIT000039141"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12631 IMAGE:4126510"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3859
/gene="LETM1"
/db_xref="GeneID:3954"
/db_xref="HGNC:HGNC:6556"
/db_xref="MIM:604407"
CDS 223..2442
/gene="LETM1"
/codon_start=1
/product="leucine zipper-EF-hand containing transmembrane
protein 1"
/protein_id="AAH21208.1"
/db_xref="GeneID:3954"
/db_xref="HGNC:HGNC:6556"
/db_xref="MIM:604407"
/translation="MASILLRSCRGRAPARLPPPPRYTVPRGSPGDPAHLSCASTLGL
RNCLNVPFGCCTPIHPVYTSSRGDHLGCWALRPECLRIVSRAPWTSTSVGFVAVGPQC
LPVRGWHSSRPVRDDSVVEKSLKSLKDKNKKLEEGGPVYSPPAEVVVKKSLGQRVLDE
LKHYYHGFRLLWIDTKIAARMLWRILNGHSLTRRERRQFLRICADLFRLVPFLVFVVV
PFMEFLLPVAVKLFPNMLPSTFETQSLKEERLKKELRVKLELAKFLQDTIEEMALKNK
AAKGSATKDFSVFFQKIRETGERPSNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLE
LQSIGTNNFLRFQLTMRLRSIKADDKLIAEEGVDSLNVKELQAACRARGMRALGVTED
RLRGQLKQWLDLHLHQEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQV
KVAEVEGEQVDNKAKLEATLQEEAAIQQEHREKELQKRSEVAKDFEPERVVAAPQRPG
TEPQPEMPDTVLQSETLKDTAPVLEGLKEEEITKEEIDILSDACSKLQEQKKSLTKEK
EELELLKEDVQDYSEDLQEIKKELSKTGEEKYVEESKASKRLTKRVQQMIGQIDGLIS
QLEMDQQAGKLAPANGMPTGENVISVAELINAMKQVKHIPESKLTSLAAALDENKDGK
VNIDDLVKVIELVDKEDVHISTSQVAEIVATLEKEEKVEEKEKAKEKAEKEVAEVKS"
BASE COUNT 854 a 1066 c 1173 g 766 t
ORIGIN
1 gcggcctggc cgccccgccc cgcgcctccg gacgtctgtg ccgggacaag gccgccgctg
61 gtgccgggtc cttgaggaga gcgcctcccg tccgaggcca gccgcctctg tcagccgtcc
121 gcgcgggccg ggtctgaagc gccgccggga cggcgaagag ccgcggccgc cgcggagaag
181 gaggcagcgc aggaggccgg agcggccgcc gcgcccgagc acatggcgtc catcttactg
241 aggagctgcc gcggccgggc gcccgcccgc ctcccgccgc cgcctcggta caccgtcccg
301 cggggtagtc caggggatcc tgctcatctc agctgtgcca gcaccctggg gttgaggaac
361 tgcctgaatg ttccatttgg ctgctgcact cccatccacc ctgtgtacac atcctccaga
421 ggcgatcacc tcggctgttg ggctctgagg cccgagtgcc ttcgcatagt gtcgagagcg
481 ccatggacct ctacctctgt gggttttgtg gctgtgggac ctcagtgcct tcctgtgcgt
541 ggctggcact cttcgcgccc tgttcgcgat gactcggtag tagagaagtc cctcaagtcc
601 ttgaaggaca agaacaagaa gctggaggaa ggcggcccgg tgtacagccc ccccgcagag
661 gtggtggtga agaagtccct ggggcagcgg gtgctggacg agctgaagca ctactaccat
721 ggcttccgcc tgctatggat cgacaccaag atcgcggcac gcatgctctg gcgcatcctc
781 aacggccaca gcctgacccg ccgggagcgc aggcagtttc tccggatctg cgctgacctc
841 ttccgcctgg tgccgttcct tgtgttcgtg gtggtgccgt tcatggagtt tctgctgcct
901 gttgctgtga agctcttccc caacatgttg ccatccacat ttgagactca gtcactcaag
961 gaggagaggc tgaagaagga gcttcgggtc aagctggagc tggccaagtt cctccaggac
1021 accatcgagg agatggcctt gaagaacaag gcagccaagg gcagcgccac caaagacttc
1081 tctgtgtttt tccagaagat ccgggaaaca ggggagaggc ccagcaatga ggaaatcatg
1141 cgtttttcca aattatttga ggatgagctg accctggaca acctgacacg gccgcagctg
1201 gtggccctgt gcaagctgct ggagctacag tccatcggca ccaacaactt cctgcgcttc
1261 cagcttacca tgcggctgcg ctccataaag gcagacgaca agctgattgc tgaggaaggg
1321 gtggacagcc tgaatgtcaa ggagctgcag gcagcgtgtc gggcacgagg catgcgggcc
1381 ctgggcgtca cggaagaccg cctgaggggt cagctgaagc agtggctgga cctgcacctg
1441 catcaggaga tccccacatc gctgctcatc ctgtcccggg ccatgtacct cccggacacc
1501 ctctctccag ccgaccagct caagtccaca ctgcagaccc tcccagagat tgtggcaaag
1561 gaagcacagg tgaaagtggc cgaggtggag ggcgagcagg tggacaacaa ggccaagctg
1621 gaggccacgc tgcaggagga ggcggccatc cagcaggagc accgtgagaa ggagctgcag
1681 aagcgctcgg aggtggcgaa ggattttgag cccgaacgtg tggtagctgc tccccaaagg
1741 ccggggaccg agccacagcc agaaatgcct gacacagtcc tgcagtcaga gaccttgaag
1801 gacactgccc cggtgctgga gggcttgaag gaggaagaga tcacgaagga ggaaatcgac
1861 atcctcagcg atgcctgctc taagctgcag gagcagaaga agtcactcac caaggagaag
1921 gaggagctgg agctgctgaa ggaggatgtg caggactaca gcgaggactt gcaggagatc
1981 aagaaggaac tttcaaagac tggtgaagaa aaatacgtgg aagaatctaa agccagcaag
2041 agattgacaa aaagggtgca gcaaatgatc gggcagatcg atggcttgat ctcgcagctg
2101 gagatggacc agcaggctgg caagctggcc ccggccaacg gcatgcccac gggggagaac
2161 gtcatcagtg tcgctgagct catcaacgcc atgaagcaag tcaagcacat tcccgaaagc
2221 aagctcacca gcctggccgc agcactggat gaaaacaagg atggcaaggt caacatcgac
2281 gacctcgtca aggtgattga gctggtggac aaagaagatg ttcacatctc caccagccag
2341 gtggctgaga ttgtagcaac actggaaaaa gaggagaagg tggaggagaa ggagaaggcc
2401 aaagagaagg cagagaagga ggtcgcagag gtgaagagct agaaccactg gcctgggcac
2461 ctgtcctcct gctgtgccgt caccctggca agggccgtga gggcgattgc tttgtggtga
2521 ttctcagtgg ctcatctaat attttggctg gaataaatca gagacttcca taatcaagta
2581 aattttaatt ttcatcattc catggagatt cagtctgtct ggaatcccgg aacccctcca
2641 cagaatcgtg tctggatcca cactgtggtg tggctgccac ggcctcctgg ctccagaggc
2701 agctgggccg ggccaaggca ggaaggcgcc cccatgtgtg tggcctcagt ctcagcatct
2761 gactgtgctg ccctgtcccc agggaagaga atgaggacca cgtggactcc gcccacacag
2821 agctggctgc tgtgcccacc ctcaggggcg tcaggagaca cagcctggcc tcctcagggc
2881 tgaagatgcc tccattcgcc tgtggacctt gatttctaga tttcagtgtc aatagacctg
2941 tcttcctgca cactttcagt tggatgtggg tcattgtgga gacagaggtg tctgccatct
3001 ctgtggcctc tggagagtga cgtctccctg ctgggagtgc tggttctcac gtgcggtttc
3061 ccttgtgtat cggagctctt tctcggcttt ctatttcccc cagttcttta agcagtcaat
3121 tggcacagag tttcccacgg gggctgcagt ggattcactg tgtcagggat gagcctggct
3181 tgggggttgg tggggctctg aagcgcattt ggggttcttt gtagcttcta atgtgaggtt
3241 tgagtccagt gcgcccacag cagcatgccc ttctcacccc ttgcagtgtt gcaggctcag
3301 gcccctgggc tccttcagca agcaggctag tcaatgaggc atgaggatcc ggcacagggc
3361 atcccctggg gcttcaaggg caataccccc gtgcttaggg tttgccctgt gccctctggg
3421 tggggtggcc tccccgcact cggcagcatg gccaggctgg ccagggcgtg ggcaggtggt
3481 gtcctgtggc acctccatcc tcctgcccag ccggctgtgt cacactcatc tttttaaggt
3541 caggttggtt cctggcaaaa atgtacctcc aggggcctcc aagcatagga tttggaagac
3601 aggaacggca caggcgtcca ggaaagcagc tgcactcaga caatgccttc tccattactt
3661 gaagcttctt tctgttcagc cattaaagaa acttgacaaa ataggaacag gagatatttc
3721 tcaattgtaa acctttgtgc agggacagtt ggcttccaga ggctttcagc tttcagttat
3781 ttgagaagtt tgttttagat ccttaactaa tatttatgaa ttctctcaaa aaaaaaaaaa
3841 aaaaaaaaaa aaaaaaaaa
//