LOCUS BC021090 2606 bp mRNA linear HUM 06-OCT-2003
DEFINITION Homo sapiens scinderin, mRNA (cDNA clone MGC:31749 IMAGE:4877906),
complete cds.
ACCESSION BC021090
VERSION BC021090.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2606)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2606)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (03-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 40 Row: n Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 14916472.
FEATURES Location/Qualifiers
source 1..2606
/db_xref="H-InvDB:HIT000039078"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:31749 IMAGE:4877906"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2606
/gene="SCIN"
/gene_synonym="KIAA1905"
/db_xref="GeneID:85477"
CDS 50..2197
/gene="SCIN"
/gene_synonym="KIAA1905"
/codon_start=1
/product="SCIN protein"
/protein_id="AAH21090.1"
/db_xref="GeneID:85477"
/translation="MARELYHEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGD
AYLVLHTAKTSRGFTYRLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGY
ESNDFVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSF
NKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPS
ELIKVLGEKPELPDGGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAM
LLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEG
GETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQIKQIPFDASKLHSSPQMAAQHNMVD
DGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYPRGQIIYTWQGANATRDEL
TTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQAPAP
PTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGA
EYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQTSPLLETQAEDHPPRLYGCSNKTG
RFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDP
SGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW"
misc_feature 101..391
/gene="SCIN"
/gene_synonym="KIAA1905"
/note="GEL; Region: Gelsolin homology domain"
/db_xref="CDD:smart00262"
misc_feature 461..730
/gene="SCIN"
/gene_synonym="KIAA1905"
/note="GEL; Region: Gelsolin homology domain"
/db_xref="CDD:smart00262"
misc_feature 803..1090
/gene="SCIN"
/gene_synonym="KIAA1905"
/note="GEL; Region: Gelsolin homology domain"
/db_xref="CDD:smart00262"
misc_feature 1235..1516
/gene="SCIN"
/gene_synonym="KIAA1905"
/note="GEL; Region: Gelsolin homology domain"
/db_xref="CDD:smart00262"
misc_feature 1577..1837
/gene="SCIN"
/gene_synonym="KIAA1905"
/note="GEL; Region: Gelsolin homology domain"
/db_xref="CDD:smart00262"
misc_feature 1904..2179
/gene="SCIN"
/gene_synonym="KIAA1905"
/note="GEL; Region: Gelsolin homology domain"
/db_xref="CDD:smart00262"
BASE COUNT 788 a 552 c 682 g 584 t
ORIGIN
1 ccaagatcag cgatatcacg cgtcccccgg agcatcgcgt gcaggagcca tggcgcggga
61 gctataccac gaagagttcg cccgggcggg caagcaggcg gggctgcagg tctggaggat
121 tgagaagctg gagctggtgc ccgtgcccca gagcgctcac ggcgacttct acgtcgggga
181 tgcctacctg gtgctgcaca cggccaagac gagccgaggc ttcacctacc gcctgcactt
241 ctggctcgga aaggagtgtt cccaggatga aagcacagct gctgccatct tcactgttca
301 gatggatgac tatttgggtg gcaagccagt gcagaataga gaacttcaag gatatgagtc
361 taatgacttt gttagctatt tcaaaggcgg tctgaaatac aaggctggag gcgtggcatc
421 tggattaaat catgttctta cgaacgacct gacagccaag aggctcctac atgtgaaggg
481 tcgtagagtg gtgagagcca cagaagttcc ccttagctgg gacagtttca acaagggtga
541 ctgcttcatc attgaccttg gcaccgaaat ttatcagtgg tgtggttcct cgtgcaacaa
601 atatgaacgt ctgaaggcaa accaggtagc tactggcatt cggtacaatg aaaggaaagg
661 aaggtctgaa ctaattgtcg tggaagaagg aagtgaaccc tcagaactta taaaggtctt
721 aggggaaaag ccagagcttc cagatggagg tgatgatgat gacattatag cagacataag
781 taacaggaaa atggctaaac tatacatggt ttcagatgca agtggctcca tgagagtgac
841 tgtggtggca gaagaaaacc ccttctcaat ggcaatgctg ctgtctgaag aatgctttat
901 tttggaccac ggggctgcca aacaaatttt cgtatggaaa ggtaaagatg ctaatcccca
961 agagaggaag gctgcaatga agacagctga agaatttcta cagcaaatga attattccaa
1021 gaatacccaa attcaagttc ttccagaagg aggtgaaaca ccaatcttca aacagttttt
1081 taaggactgg agagataaag atcagagtga tggcttcggg aaagtttatg tcacagagaa
1141 agtggctcaa ataaaacaaa ttccctttga tgcctcaaaa ttacacagtt ctccgcagat
1201 ggcagcccag cacaatatgg tggatgatgg ttctggcaaa gtggagattt ggcgtgtaga
1261 aaacaatggt aggatccaag ttgaccaaaa ctcatatggt gaattctatg gtggtgactg
1321 ctacatcata ctctacacct atcccagagg acagattatc tacacgtggc aaggagcaaa
1381 tgccacacga gatgagctga caacatctgc gttcctgact gttcagttgg atcggtccct
1441 tggaggacag gctgtgcaga tccgagtctc ccaaggcaaa gagcctgttc acctactgag
1501 tttgttcaaa gacaaaccgc tcattattta caagaatgga acatcaaaga aaggaggtca
1561 ggcacctgct ccccctacac gcctctttca agtccggaga aacctggcat ctatcaccag
1621 aattgtggag gttgatgttg atgcaaattc actgaattct aacgatgttt ttgtcctgaa
1681 actgccacaa aatagtggct acatctgggt aggaaaaggt gctagccagg aggaggagaa
1741 aggagcagag tatgtagcaa gtgtcctaaa gtgcaaaacc ttaaggatcc aagaaggcga
1801 ggagccagag gagttctgga attcccttgg agggaaaaaa gactaccaga cctcaccact
1861 actggaaacc caggctgaag accatccacc tcggctttac ggctgctcta acaaaactgg
1921 aagatttgtt attgaagaga ttccaggaga gttcacccag gatgatttag ctgaagatga
1981 tgtcatgtta ctagatgctt gggaacagat atttatttgg attggcaaag atgctaatga
2041 agttgagaaa aaagaatctc tgaagtctgc caaaatgtac cttgagacag acccttctgg
2101 aagagacaag aggacaccaa ttgtcatcat aaaacagggc catgagccac ccacattcac
2161 aggctggttc ctgggctggg attccagcaa gtggtaaatt ggtatttgta aaaagcaaac
2221 aaacattaca aggcagttat ctcattgctg ttttgggaga ggaacgggaa aagctttttg
2281 cttatttgtc ttttgaaaat taaggctggg cgcggtggct cacacctgta atcccagcac
2341 tttgagagga tgaggtaggc ggatcactgg ggtcaggatt tcgagaccag cctggccaac
2401 atggcgaaac ctcgcctcta ctaaaaatac aaaaaaatta gctgcgcgtg gtggtgcacg
2461 cctgtagtcc ctgctacttg gaaggctgag acaggaaaat tgcttgaacc caggaggctg
2521 aggttgcagt gagccaggat tgcgccacca cactccagcc tgggcaacag agactctgtc
2581 tcaaaaaaaa aaaaaaaaaa aaaaaa
//