LOCUS BC020988 3074 bp mRNA linear HUM 21-JUL-2008
DEFINITION Homo sapiens apoptosis enhancing nuclease, mRNA (cDNA clone
MGC:9730 IMAGE:3852419), complete cds.
ACCESSION BC020988
VERSION BC020988.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3074)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3074)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 20 Row: o Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21362093.
FEATURES Location/Qualifiers
source 1..3074
/db_xref="H-InvDB:HIT000039071"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9730 IMAGE:3852419"
/tissue_type="Colon, adenocarcinoma"
/clone_lib="NIH_MGC_65"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3074
/gene="AEN"
/gene_synonym="pp12744"
/db_xref="GeneID:64782"
/db_xref="HGNC:HGNC:25722"
/db_xref="MIM:610177"
CDS 90..1067
/gene="AEN"
/gene_synonym="pp12744"
/codon_start=1
/product="apoptosis enhancing nuclease"
/protein_id="AAH20988.1"
/db_xref="GeneID:64782"
/db_xref="HGNC:HGNC:25722"
/db_xref="MIM:610177"
/translation="MVPREAPESAQCLCPSLTIPNAKDVLRKRHKRRSRQHQRFMARK
ALLQEQGLLSMPPEPGSSPLPTPFGAATATEAASSGKQCLRAGSGSAPCSRRPAPGKA
SGPLPSKCVAIDCEMVGTGPRGRVSELARCSIVSYHGDVLYDKYIRPEMPIADYRTRW
SGITRQHMRKAVPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTRDTTYVP
NFLSEPGLHTRARVSLKDLALQLLHKKIQVGQHGHSSVEDATTAMELYRLVEVQWEQQ
EARSLWTCPEDREPDSSTDMEQYMEDQYWPDDLAHGSRGGAREAQDRRN"
BASE COUNT 679 a 830 c 875 g 690 t
ORIGIN
1 ccggaagaga cacgcggggc ttcaggctgc tgccccattg gaagattact ccccaggctt
61 cccttgcccc aagcagtgag ctgactggaa tggtaccccg ggaggcccct gagtctgctc
121 agtgcctgtg cccttccctc accatcccaa atgccaagga tgtgcttcgg aagaggcaca
181 agagaaggag ccgacagcac cagcggttca tggcccggaa ggccttgctg caggagcagg
241 ggctgctgag catgcctcca gaaccagggt cctccccact gcccacccct ttcggggcag
301 cgacagcaac tgaagctgcc agcagtggga agcagtgtct gagggctgga tctggcagtg
361 ccccatgcag cagaaggcct gctcccggga aagcctcagg gcccttgccc agcaagtgtg
421 tggctatcga ctgtgagatg gtgggcacgg gaccccgagg gcgggtaagc gagctggccc
481 gctgttccat tgtgagctac catggcgatg tcctctatga caagtacatc aggcctgaga
541 tgcccatcgc tgactaccgt acccgctgga gtggcatcac tcggcagcac atgcgcaagg
601 ctgtcccctt ccaggtggcc cagaaagaga tccttaagct cctgaagggc aaggtggtgg
661 tggggcacgc gctgcacaac gacttccagg cgctcaagta tgtccaccct cggagccaga
721 cccgggatac cacctatgtc ccaaacttcc tcagcgagcc cggcctccac acccgggccc
781 gggtctctct aaaggacctg gccctgcagc tgctgcacaa gaagatccag gtgggccagc
841 acgggcactc atcagtagaa gatgccacga cagccatgga gctctaccgg ctggtggagg
901 tgcagtggga acagcaggag gcccgcagcc tctggacctg ccccgaggac agagaacctg
961 acagcagcac agacatggaa cagtacatgg aggaccagta ctggcccgat gacctggccc
1021 acggcagcag aggaggagcc agggaggcac aggacagaag gaattgagaa gggggcgggg
1081 ctccctggct gggcttccgg tgtggccggt aggaagtggg ggccaggaga gcagcgggca
1141 ctccttcctg ggcagggtgg ggcaggatgc agtgagccag ccccagggcc agaggagttg
1201 gggtcatctg ttaccttgac accctctgca cacagcatag ccctctctct ctccagggct
1261 gttggttctt tctcctgact cctgtggttt tgctaatggc actttacaga ctccatggag
1321 atgtcaggtg gaccatcttc tagggcccag caggagtagg gaatgtgcca acagactgcc
1381 caggttgccg tggccttccc caccccccag atctcctgag tcatcatgct gtgctaatga
1441 aagggatcat atcatcctct ctggggatgg tgggtggggg tgtcaatatc ctggagctcc
1501 cttaccccaa ctcaatgact tgggggtaaa gttctcttcc ttttgttgcc tacctcttcc
1561 tccactcatt tgggttcaga ataaacatgc cctgaagtta aaggggagtt aagtcctaaa
1621 ggaggcattt cttccccacc tccctgacct ggaactctgg ctacagccat tgtaggaact
1681 ccgtgcctgg cctgtcagct ccctgctagg ctacagtgga atagcagagc ccacaggctt
1741 ctcgtgggga gttggctcct taacatttct tggcaacaga aagccccagg cacagctcag
1801 ggaggaggga aggcaggtaa gctttggacg agaactggca tatttatttt gacccaaatc
1861 agggatttcc ccagtccacc cagtactggg ctcttaagca aaagtctgag aaacaagaca
1921 gtggtttgaa ttctggggcc tttgtgtagg attgtgcctg acctttattt atttattaac
1981 agcagggcca ctcgtctagg gcagtggagt ctgcgtgtct cctggggctg gggcagggca
2041 ttggcagtta cgcagtggcc ctgaacctgg tctggtgccc ccgaacctgg tctgatgccc
2101 cctcagctct ttgacaatca ctgtggctgt tgggttttct cctatttcta aaaatgttct
2161 cttctttcct aagtgacagt tttgaagtat tggataacca agagctcagg tcacacagac
2221 cttggagccc catctttgct tgcagcttag ctttgagata ctaagcaagc gagggacttc
2281 actcttgagc ctgttttttc ctcatctgta aagtggggat agtggtacgg cctacctcat
2341 agggttgtaa tgagcactaa atgtgaagtg cttggcacag tgcctggcac atggtgagcc
2401 acagctactg tgagtttctg tttatccccc tttttttttt tttaagccca ttgtttattc
2461 tttgagaatt tgttgtaact tcttcaggat aacacctgag tccacaggct gagcagctgt
2521 ggcccagaca gaactgctcc ggcttggctg ttccagcagg tggggcgctg gcctcggtga
2581 gggcacagca gcaaggttca cggatatccg tgtgtcttgt ctgtggccac caggcacagg
2641 tttggcttcc ggtcagtgtc ccgacactgt gcgggaggtg acaacagagc aaagcagcgc
2701 aggggtcagg gaggtggaga cactgctgaa atcacactac cccaccctca gctgaagccc
2761 cacgttccac aaacttgggg tcatagattg tccagtcact ggctccctcc ctgtcagcac
2821 agcacagagg aaggggctaa ctgaatcttt taccacttct ggcctggctc cagaactttg
2881 ttctagattc cttaaaagtc ggtagctgat gtcaaactca attgagcagt agctttgatc
2941 ccttggtctg ggggtcgaag gaagatggcg ctgttatcag cggggaaatg tactatttaa
3001 gatcagcttt gttgtaaaac catttgttct agaataaaac tcaattggaa acgtgaaaaa
3061 aaaaaaaaaa aaaa
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