LOCUS BC020744 1219 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens aldo-keto reductase family 1, member C4 (chlordecone
reductase; 3-alpha hydroxysteroid dehydrogenase, type I;
dihydrodiol dehydrogenase 4), mRNA (cDNA clone MGC:22581
IMAGE:4734943), complete cds.
ACCESSION BC020744
VERSION BC020744.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1219)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1219)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CLONTECH
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 37 Row: j Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24497584.
FEATURES Location/Qualifiers
source 1..1219
/db_xref="H-InvDB:HIT000038930"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22581 IMAGE:4734943"
/tissue_type="Liver"
/clone_lib="NIH_MGC_76"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1219
/gene="AKR1C4"
/gene_synonym="3-alpha-HSD"
/gene_synonym="C11"
/gene_synonym="CDR"
/gene_synonym="DD4"
/gene_synonym="HAKRA"
/gene_synonym="MGC22581"
/db_xref="GeneID:1109"
/db_xref="HGNC:HGNC:387"
/db_xref="MIM:600451"
CDS 34..1005
/gene="AKR1C4"
/gene_synonym="3-alpha-HSD"
/gene_synonym="C11"
/gene_synonym="CDR"
/gene_synonym="DD4"
/gene_synonym="HAKRA"
/gene_synonym="MGC22581"
/codon_start=1
/product="aldo-keto reductase family 1, member C4
(chlordecone reductase; 3-alpha hydroxysteroid
dehydrogenase, type I; dihydrodiol dehydrogenase 4)"
/protein_id="AAH20744.1"
/db_xref="GeneID:1109"
/db_xref="HGNC:HGNC:387"
/db_xref="MIM:600451"
/translation="MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEA
GFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESS
LKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLA
KSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSA
LGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQR
IRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPFSDEY"
BASE COUNT 371 a 271 c 279 g 298 t
ORIGIN
1 acaggatctg cttagtgaaa gaagtggcaa gcaatggatc ccaaatatca gcgtgtagag
61 ctaaatgatg gtcacttcat gcccgtattg ggatttggca cctatgcacc tccagaggtt
121 ccgaggaaca gagctgtaga ggtcaccaaa ttagcaatag aagctggctt ccgccatatt
181 gattctgctt atttatacaa taatgaggag caggttggac tggccatccg aagcaagatt
241 gcagatggca gtgtgaagag agaagacata ttctacactt caaagctttg gtgcactttc
301 tttcaaccac agatggtcca accagccttg gaaagctcac tgaaaaaact tcaactggac
361 tatgttgacc tctatcttct tcatttccca atggctctca agccaggtga gacgccacta
421 ccaaaagatg aaaatggaaa agtaatattc gacacagtgg atctctctgc cacatgggag
481 gtcatggaga agtgtaagga tgcaggattg gccaagtcca tcggggtgtc aaacttcaac
541 tacaggcagc tggagatgat cctcaacaag ccaggactca agtacaagcc tgtctgcaac
601 caggtagaat gtcatcctta cctcaaccag agcaaactgc tggatttctg caagtcaaaa
661 gacattgttc tggttgccca cagtgctctg ggaacccaac gacataaact atgggtggac
721 ccaaactccc cagttctttt ggaggaccca gttctttgtg ccttagcaaa gaaacacaaa
781 cgaaccccag ccctgattgc cctgcgctac cagctgcagc gtggggttgt ggtcctggcc
841 aagagctaca atgagcagcg gatcagagag aacatccagg tttttgaatt ccagttgaca
901 tcagaggata tgaaagttct agatggtcta aacagaaatt atcgatatgt tgtcatggat
961 tttcttatgg accatcctga ttatccattt tcagatgaat attagcatag agggtgttgc
1021 acgacatcta gcagaaggcc ctgtgtgtgg atggtgatgc agaggatgtc tctatgctgg
1081 tgactggaca cacggcctct ggttaaatcc ctcccctcct gcttggcaac ttcagctagc
1141 tagatatatc catggtccag aaagcaaaca taataaattt ttatcttgaa ctaaaaaaaa
1201 aaaaaaaaaa aaaaaaaaa
//