LOCUS BC020677 1442 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens histamine N-methyltransferase, mRNA (cDNA clone
MGC:22386 IMAGE:4767331), complete cds.
ACCESSION BC020677
VERSION BC020677.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1442)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1442)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CLONTECH
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 37 Row: k Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 66932961.
FEATURES Location/Qualifiers
source 1..1442
/db_xref="H-InvDB:HIT000038890"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22386 IMAGE:4767331"
/tissue_type="Liver"
/clone_lib="NIH_MGC_76"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1442
/gene="HNMT"
/gene_synonym="HMT"
/gene_synonym="HNMT-S1"
/gene_synonym="HNMT-S2"
/db_xref="GeneID:3176"
/db_xref="HGNC:HGNC:5028"
/db_xref="MIM:605238"
CDS 14..892
/gene="HNMT"
/gene_synonym="HMT"
/gene_synonym="HNMT-S1"
/gene_synonym="HNMT-S2"
/codon_start=1
/product="histamine N-methyltransferase"
/protein_id="AAH20677.1"
/db_xref="GeneID:3176"
/db_xref="HGNC:HGNC:5028"
/db_xref="MIM:605238"
/translation="MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGII
GRIGDTKSEIKILSIGGGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELV
AKTSNLENVKFAWHKETSSEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHS
LLGTNAKMLIIVVSGSSGWDKLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECY
DLLSTMDISDCFIDGDENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKE
GKVLFNNTLSFIVIEA"
BASE COUNT 490 a 259 c 273 g 420 t
ORIGIN
1 gagaaaacca aatatggcat cttccatgag gagcttgttt tctgaccacg ggaaatatgt
61 tgaatctttc cggaggtttc tcaaccattc cacggaacac cagtgcatgc aggaattcat
121 ggacaagaag ctgccaggca taataggaag gattggagac acaaaatcag aaattaagat
181 tctaagcata ggcggaggtg caggtgaaat tgatcttcaa attctctcca aagttcaggc
241 tcaataccca ggagtttgta tcaacaatga agttgttgag ccaagtgctg aacaaattgc
301 caaatacaaa gagcttgtag ccaagacatc gaacctcgag aacgtaaagt ttgcttggca
361 taaggagaca tcatctgaat accaaagtag aatgttggag aaaaaggagc ttcaaaagtg
421 ggactttatt catatgattc aaatgctgta ttatgtaaaa gacatcccag ctaccctgaa
481 attcttccat agtctcttag gtaccaatgc taagatgctc attattgttg tgtcaggaag
541 cagtggctgg gacaagctgt ggaaaaagta cggatcacgc tttccccagg atgacctctg
601 ccagtatatc acatcagatg acctcactca gatgctggac aacctagggc ttaagtatga
661 gtgctatgac cttttgtcca ccatggatat atctgactgc tttattgatg gtgatgaaaa
721 tggagacctg ctttgggatt ttttgactga aacctgcaac tttaatgcca cagcaccacc
781 tgatctcaga gcagagcttg ggaaagatct acaagagcct gaatttagtg ctaagaaaga
841 ggggaaggtt ctttttaata atactctgag tttcatagtg attgaggcat aactatcaat
901 cacaaaagta tattcaaaaa ttatattttg aacaactcga atcactcatt tatttccata
961 ttaaaatcac aaactcatcc attaatgtag ataaagcact gtttggatat gagatgtagc
1021 aaattccaat acattattgg acttccattt ggaatcatat gggatactgc tggtcttatc
1081 ctgtccctcc tccaggtaga gagaccacaa gcaggctcaa cataacataa gctagaaaaa
1141 ttagatgact gaatttctat ggcatattga taataaaatt cattccattt gctgattgtc
1201 tgaaattttc tagaatacta ataaaataca tactatagat tctttattag tgaagtatgc
1261 actaatcaat actttgaaca caaagcctgt gttactgatt tggccgtttt gtgaagaaac
1321 atttatcttt gtacgttctt ctattgtgct ttctatctaa tttttattaa tttgtaagag
1381 taagcacctt tagaatatta aaaattaatt ctccaaaaaa aaaaaaaaaa aaaaaaaaaa
1441 aa
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