LOCUS BC020586 4202 bp mRNA linear HUM 07-OCT-2003
DEFINITION Homo sapiens splicing factor, arginine/serine-rich 14, mRNA (cDNA
clone MGC:22011 IMAGE:4400185), complete cds.
ACCESSION BC020586
VERSION BC020586.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4202)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4202)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (03-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 27 Row: f Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis, GenomeScan gene prediction.
FEATURES Location/Qualifiers
source 1..4202
/db_xref="H-InvDB:HIT000038837"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22011 IMAGE:4400185"
/tissue_type="Duodenum, adenocarcinoma"
/clone_lib="NIH_MGC_88"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4202
/gene="SFRS14"
/gene_synonym="KIAA0365"
/db_xref="GeneID:10147"
/db_xref="MIM:607993"
CDS 223..3189
/gene="SFRS14"
/gene_synonym="KIAA0365"
/codon_start=1
/product="SFRS14 protein"
/protein_id="AAH20586.1"
/db_xref="GeneID:10147"
/db_xref="MIM:607993"
/translation="MYDDVHSDGRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPS
ISDDSYFRKECGRDLEFSHSDSRDQVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQ
ESSWSQEYSFGPSAVLGDFGSSRLIEKECLEKESRDYDVDHPGEADSVLRGSSQVQAR
GRALNIVDQEGSLLGKGETQGLLTAKGGVGKLVTLRNVSTKKIPTVNRITPKTQGTNQ
IQKNTPSPDVTLGTNPGTEDIQFPIQKIPLGLDLKNLRLPRRKMSFDIIDKSDVFSRF
GIEIIKWAGFHTIKDDIKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIK
FLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKSVTPLL
MACNAYELSVKMKTLSNPLDLALALETTNSLCRKSLALLGQTFSLASSFRQEKILEAV
GLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGCPLQVKKAEPEPMREEEKMIP
PTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEGSLSPKERTLLKEDPAYWF
LSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRAMLYSRAVRNLKKKLLP
WQRRGLLRAQGLRGWKARRATTGTQTLLSSGTRLKHHGRQAPGLSQAKPSLPDRNDAA
KDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADIDMKTMETAEKLA
RFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPSICFTSSPHNL
HTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELESPEASSGTCFPRKRISSKSLKV
GMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQQKLTDKNLGFQM
LQKMGWKEGHGLGSLGKGIREPVSVYAAGSLGWEWVGPQSFHLQPAAWLLHSQDGLQL
AVDFCFLNRRHLQMRS"
misc_feature 1828..1983
/gene="SFRS14"
/gene_synonym="KIAA0365"
/note="Surp; Region: Surp module. This domain is also
known as the SWAP domain. SWAP stands for
Suppressor-of-White-APricot. It has been suggested that
these domains may be RNA binding"
/db_xref="CDD:pfam01805"
misc_feature 2419..2583
/gene="SFRS14"
/gene_synonym="KIAA0365"
/note="Surp; Region: Surp module. This domain is also
known as the SWAP domain. SWAP stands for
Suppressor-of-White-APricot. It has been suggested that
these domains may be RNA binding"
/db_xref="CDD:pfam01805"
misc_feature 2941..3066
/gene="SFRS14"
/gene_synonym="KIAA0365"
/note="G-patch; Region: G-patch domain. This domain is
found in a number of RNA binding proteins, and is also
found in proteins that contain RNA binding domains. This
suggests that this domain may have an RNA binding
function. This domain has seven highly conserved glycines"
/db_xref="CDD:pfam01585"
BASE COUNT 1120 a 1047 c 1047 g 988 t
ORIGIN
1 ggcctcccag agactcgcgg acgctcacga taaccaagga cgaccgcgaa ccaagggcaa
61 aataacatgg cagccagacg aattacacag gagacttttg atgctgtatt acaagaaaaa
121 gccaaacgat atcacatgga tgccagtggt gaggctgtaa gcgaaactct tcagtttaaa
181 gctcaagatc tcttaagggc agtcccaaga tccagagcag agatgtatga tgacgtccac
241 agcgatggca gatactccct cagtggatct gtagctcact ctagagatgc cggaagagaa
301 ggcctgagaa gtgacgtatt tccagggcct tccttcagat caagcaaccc ttccatcagt
361 gatgacagct actttcgcaa agaatgtggc cgggatctgg aattttctca ctctgattct
421 cgggaccagg tcattggcca ccggaaattg gggcatttcc gttctcagga ctggaaattt
481 gcgctccgtg gttcttggga acaagacttt ggccatccag tttctcaaga gtcctcttgg
541 tcacaggagt atagttttgg tccctctgca gttttggggg actttggatc ttccaggctg
601 attgagaaag agtgtttgga gaaggagagt cgggattatg acgtggacca tcctggggag
661 gctgactctg tgcttagggg cagcagtcaa gtccaggcca gaggtcgagc tctaaacatc
721 gttgaccagg aaggttccct cctaggaaag ggggagactc agggcctgct cacagctaag
781 gggggtgttg ggaaacttgt cacattgaga aatgtgagca caaaaaaaat acccaccgtg
841 aatcgtatta ctcccaaaac tcagggcact aaccaaatcc agaaaaacac tccaagtcct
901 gatgtgaccc tggggacaaa cccagggaca gaagatatcc agttccccat tcagaagatc
961 cctctggggc tggatctgaa gaatcttcgg ctccccagaa gaaagatgag ctttgacatc
1021 atagataagt ctgatgtttt ttcaagattt gggatagaaa taatcaaatg ggcaggattc
1081 cacaccataa aagatgatat taaattttcc caacttttcc agactctctt tgaacttgaa
1141 acagaaacct gtgctaaaat gcttgcctca ttcaaatgtt ccttaaaacc agagcacaga
1201 gatttttgct tttttactat caaattttta aagcactctg ctttgaaaac acccagagtt
1261 gataatgagt ttttaaacat gcttttagac aaaggtgctg tgaagaccaa aaattgcttt
1321 tttgaaatca taaagccttt tgacaagtac ataatgagac ttcaagaccg gcttctgaag
1381 agtgtcacac ctttgcttat ggcctgcaat gcctacgagc taagtgtcaa gatgaagacc
1441 ctcagtaacc ccctggactt ggctcttgcc ctagaaacca ccaactctct ctgccggaag
1501 tctttggccc ttttgggaca gacattttcc ttggcctctt ctttccggca ggagaaaatc
1561 ttagaagctg tcggcctgca agatatagct ccctcacctg ctgcgtttcc aaacttcgaa
1621 gactccactt tgtttgggcg agagtacata gaccacctga aggcctggct agtcagcagc
1681 ggatgtcccc tccaggttaa gaaagccgaa ccagagccga tgcgagagga ggagaaaatg
1741 attcctccta cgaaacctga aattcaggcc aaggctccaa gtagtctgag tgatgctgtc
1801 ccccagcgag cagatcacag ggtagtgggc accatcgacc agcttgtgaa acgtgtcatc
1861 gaaggcagcc tgtctcccaa agagagaact cttctcaaag aggaccctgc ttactggttt
1921 ttgtctgatg aaaatagtct ggagtataaa tattacaagc tgaagttggc agaaatgcag
1981 cggatgagcg agaacttgcg aggagccgac cagaagccga cctcagcaga ctgtgcagtg
2041 agggccatgc tgtactcccg ggctgtccgc aacctcaaga agaaactcct tccgtggcag
2101 cggcgggggc tcctccgtgc tcaagggctc cggggctgga aggcgaggag agcgaccacc
2161 gggacccaga ccctcctatc ctcaggcacc aggctgaaac accacggccg gcaggctcca
2221 ggcctctcac aggcaaaacc atccctgcca gacagaaatg atgctgccaa ggactgcccg
2281 ccagacccag ttggaccttc tcctcaggac cccagcttag aagcctcagg cccatccccc
2341 aagccagcag gagtggacat ctctgaagca cctcagacct cttctccctg cccatctgct
2401 gacattgaca tgaagacaat ggagactgca gagaaactgg ctagatttgt tgctcaggtg
2461 ggaccagaga tcgaacaatt cagcatagaa aacagcaccg ataaccctga cctgtggttt
2521 ctacatgacc aaaatagttc tgctttcaaa ttctatcgaa agaaagtgtt tgaactatgt
2581 ccatcaattt gtttcacgtc atctccgcac aaccttcaca ctggtggtgg tgacaccacg
2641 ggttctcagg agagccccgt ggacctcatg gaaggggaag cagagtttga agacgagccc
2701 cctccgcggg aggctgagct ggagagccca gaggcctcct caggtacctg cttccctcgg
2761 aagaggatca gcagcaagtc attgaaggtt ggcatgattc cagctcccaa gagagtgtgt
2821 ctcatccagg agccaaaagt ccatgaacca gttcgaattg cctatgacag gcctcggggt
2881 cgtcccatgt ccaaaaagaa gaaacccaag gacttggact tcgcccagca gaagctgacc
2941 gataagaacc tgggcttcca gatgctgcag aagatgggct ggaaggaggg ccatggcctg
3001 ggctccctcg gaaagggcat cagggagccg gtcagcgtgt acgcagcagg cagcctgggg
3061 tgggagtggg tggggcctca gtccttccac ctgcagcctg ccgcttggct ccttcacagc
3121 caagatggct tacagctggc agttgatttt tgttttttaa acagaaggca tcttcagatg
3181 agaagctgat catttacatg tgcaggtgtt tacagggttc ctttctgtcc tggtgtagat
3241 tttttaacca gcttgttggc cctggtcatt ttggccacat ttgtgaccat cataaaagct
3301 aagtggtatt tctgtgtagt ttccgtctgg aactgctttc ccattcccgg gaacccatag
3361 ccgggccagc cagggtcccg aacacaggcc caaagtttat taaaccccga tcataacctc
3421 cagcaggcat ttcatttaat actgagctta gttcctgctg ggtaaggcat tccgaggtaa
3481 ccagggccct ctgggcaccc cctcaaaagc cagctcttcg agggtgagta ctccttgttt
3541 ctactgtgag tcgcgtcttg attttccctt tctttgatgt ctcagtgtgt gtcccaaaca
3601 cctgcatctc atggactgtt tgtgcccatg cccagttcct ggcatgccag gccctgggct
3661 caggtgcaca actgactctc tttttcactc cctaggggaa ccccctcgga aggggaaggg
3721 ttgggtgctg acgggcagga gcacaaagaa gacacattcg atgtgttccg acagaggatg
3781 atgcagatgt acagacacaa gcgggccaac aaatagatca aaaccactga tgtgaaagat
3841 aagccttgaa gcagcaattg cccttaaaac atcatccctg ccctggatcg gcctggagcc
3901 agtgcccaat tccagggtca cccccgagag gacaacaggc atctggaagt gctctctcgc
3961 cactctgggt gctttactgt ctctggcttg tttccatcac tggaaatcac ttagagaatt
4021 gtagtgtttt tggtccttga taaagcctag aagacatttg tgatgttaca aaatggaagt
4081 tttcttttgt ttctgttttt taagatctaa gaagttgtga atgttgttaa tcatttagcc
4141 gttgcaataa atgtagagga aatgcagtga aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
4201 aa
//