LOCUS BC020232 2686 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens farnesyltransferase, CAAX box, beta, mRNA (cDNA clone
MGC:31935 IMAGE:4652202), complete cds.
ACCESSION BC020232
VERSION BC020232.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2686)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2686)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 40 Row: h Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 42476119.
FEATURES Location/Qualifiers
source 1..2686
/db_xref="H-InvDB:HIT000038769"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:31935 IMAGE:4652202"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2686
/gene="FNTB"
/gene_synonym="FPTB"
/gene_synonym="MGC31935"
/db_xref="GeneID:2342"
/db_xref="HGNC:HGNC:3785"
/db_xref="MIM:134636"
CDS 16..1329
/gene="FNTB"
/gene_synonym="FPTB"
/gene_synonym="MGC31935"
/codon_start=1
/product="farnesyltransferase, CAAX box, beta"
/protein_id="AAH20232.1"
/db_xref="GeneID:2342"
/db_xref="HGNC:HGNC:3785"
/db_xref="MIM:134636"
/translation="MASPSSFTYYCPPSSSPVWSEPLYSLRPEHARERLQDDSVETVT
SIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPW
LCYWILHSLELLDEPIPQIVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNAL
CIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIIT
PDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQW
VTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQA
LQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPEN
ALQPTHPVYNIGPDKVIQATTYFLQKPVPGFEELKDETSAEPATD"
BASE COUNT 625 a 737 c 687 g 637 t
ORIGIN
1 gctgctctcc tgatcatggc ttctccgagt tctttcacct actattgccc tccatcttcc
61 tcccccgtct ggtcagagcc gctgtacagt ctgaggcccg agcacgcgcg agagcggttg
121 caggacgact cggtggaaac agtcacgtcc atagaacagg caaaagtaga agaaaagatc
181 caagaggtct tcagttctta caagttcaac caccttgtac caaggcttgt tttgcagagg
241 gagaagcact tccattatct gaaaagaggc cttcgacaac tgacagatgc ctatgagtgt
301 ctggatgcca gccgcccatg gctctgctat tggatcctgc acagcttgga actgctagat
361 gaacccatcc cccagatagt ggctacagat gtgtgtcagt tcctggagct gtgtcagagc
421 ccagaaggtg gctttggagg aggacccggt cagtatccac accttgcacc cacatatgca
481 gcagtcaatg cattgtgcat cattggcacc gaggaggcct atgacatcat taacagagag
541 aagcttcttc agtatttgta ctccctgaag caacctgacg gctcctttct catgcatgtc
601 ggaggtgagg tggatgtgag aagcgcatac tgtgctgcct ccgtagcctc gctgaccaac
661 atcatcactc cagacctctt tgagggcact gctgaatgga tagcaaggtg tcagaactgg
721 gaaggtggca ttggcggggt accagggatg gaagcccatg gtggctatac cttctgtggc
781 ctggccgcgc tggtaatcct caagagggaa cgttccttga acttgaagag cttattacaa
841 tgggtgacaa gccggcagat gcgatttgaa ggaggatttc agggccgctg caacaagctg
901 gtggatggct gctactcctt ctggcaggcg gggctcctgc ccctgctcca ccgcgcactg
961 cacgcccaag gtgaccctgc ccttagcatg agccactgga tgttccatca gcaggccctg
1021 caggagtaca tcctgatgtg ctgccagtgc cctgcggggg ggcttctgga taaacctggc
1081 aagtcgcgtg atttctacca cacctgctac tgcctgagcg gcctgtccat agcccagcac
1141 ttcggcagcg gagccatgtt gcatgatgtg gtcctgggtg tgcccgaaaa cgctctgcag
1201 cccactcacc cagtgtacaa cattggacca gacaaggtga tccaggccac tacatacttt
1261 ctacagaagc cagtcccagg ttttgaggag cttaaggatg agacatcggc agagcctgca
1321 accgactaga ggacctgggt cccggcagct ctttgctcac ccatctcccc agtcagacaa
1381 ggtttatacg tttcaataca tactgcattc tgtgctacac aagccttagc ctcagtggag
1441 ctgtggttct cttggtactt tcttgtcaaa caaaaccaat ggctctgggt ttggagaaca
1501 cagtggctgg ttttaaaaat tctttccaca cctgtcaaac caaaaatcta tcagcccacg
1561 tggtgtggtt ggtgaacagt gcatgccagg aggaagcagt ccctcctcac cagctctcca
1621 gccaggacga tcacacagag atgaatggca tctgagtatt acggcatcca gagccactgc
1681 tgactcccac ttgcacgcca ccattcagtc accagactgg gtgccctccg atgggtggaa
1741 taagtctgct tcatgccaag gctgggcttt gggtcccacc aagatgagtt ctctgtaaga
1801 ctgtggtgga gttgcaccag gaggtgcctc tgcctctcga cttgcaccct ggtcatttgt
1861 aagggaaaag agctggaggt ggggagagaa agatctcctt cagttgggag tccttccact
1921 tcaacactgg agaactgagc cttgcatctc tccagggtcc aaggccacgc ttggtgcaca
1981 ggcaagactt gcttcagccc caggtgtggt gacttagacc taggaaacca attatgagtg
2041 gaaagtgacc ctctagttca actgtgccag aggaaacagc cctccagtgc ccacctgcct
2101 cactcctccc tatcatgtac cgtgaaaacc ccctctgatg gcctcaaggc agtgcctgca
2161 ggccgaggcc cttctggggg tttctatctt tcttccacca gactccaagc ccactctcct
2221 ccaagactgt gttgtctttt ctcaccaaga gtattaacac tactaagtct ttcaccttaa
2281 cttatgactc aggatttatt cacgtcctgc ccactctagg ctcacaggaa taaaatcaag
2341 tgctagacac actggctgct actaaggcac tagcctctgt agctggtggt ggcagcgtgg
2401 ggtgccgccc agcgtgctgg gtcctggcag tgcctctgct gtgctgcaca ttgagccctt
2461 tctcagtcag tggagtatca agttgggcca tctgtctact gacctggcct tcatgtaagc
2521 agctgtgggc tgcgggcaga caggagctca gagatgcagc atgaggcgct tagaaaaacc
2581 tggccatttg ctgcctctaa ttcccttttg ctttgccata ttgggctatg tattacctcc
2641 ttgaaataat aaaagaataa cattttcaaa aaaaaaaaaa aaaaaa
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