LOCUS BC020090 2928 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens fragile X mental retardation, autosomal homolog 2,
mRNA (cDNA clone MGC:21187 IMAGE:4385430), complete cds.
ACCESSION BC020090
VERSION BC020090.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2928)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2928)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 26 Row: o Column: 8.
FEATURES Location/Qualifiers
source 1..2928
/db_xref="H-InvDB:HIT000038732"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:21187 IMAGE:4385430"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2928
/gene="FXR2"
/db_xref="GeneID:9513"
/db_xref="HGNC:HGNC:4024"
/db_xref="MIM:605339"
CDS 320..2341
/gene="FXR2"
/codon_start=1
/product="fragile X mental retardation, autosomal homolog
2"
/protein_id="AAH20090.1"
/db_xref="GeneID:9513"
/db_xref="HGNC:HGNC:4024"
/db_xref="MIM:605339"
/translation="MGGLASGGDVEPGLPVEVRGSNGAFYKGFVKDVHEDSVTIFFEN
NWQSERQIPFGDVRLPPPADYNKEITEGDEVEVYSRANEQEPCGWWLARVRMMKGDFY
VIEYAACDATYNEIVTLERLRPVNPNPLATKGSFFKVTMAVPEDLREACSNENVHKEF
KKALGANCIFLNITNSELFILSTTEAPVKRASLLGDMHFRSLRTKLLLMSRNEEATKH
LETSKQLAAAFQEEFTVREDLMGLAIGTHGANIQQARKVPGVTAIELGEETCTFRIYG
ETPEACRQARSYLEFSEDSVQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRVEGDNDK
KNPREEGMVPFIFVGTRENISNAQALLEYHLSYLQEVEQLRLERLQIDEQLRQIGLGF
RPPGSGRGSGGSDKAGYSTDESSSSSLHATRTYGGSYGGRGRGRRTGGPAYGPSSDVS
TASETESEKREEPNRAGPGDRDPPTRGEESRRRPTGGRGRGPPPAPRPTSRYNSSSIS
SVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASARRRRSRRRRTDEDRTVMDGGLES
DGPNMTENGLEDESRPQRRNRSRRRRNRGNRTDGSISGDRQPVTVADYISRAESQSRQ
RPPLERTKPSEDSLSGQKGDSVSKLPKGPSENGELSAPLELGSMVNGVS"
BASE COUNT 638 a 831 c 901 g 558 t
ORIGIN
1 gcggcagcag cgggtcccgg gactgaggca gcagcggggg cggcggcggg cggaagctga
61 ggtgacgaag gcagcggcgg cggcggccgt ttccctcacg gtggcggaga ccaaggcggc
121 ggcggcggac ggggagcggc ccggccccgg ccccctgctc gttggctgtg gcagggccgc
181 cgtggggccg gcccggctcc cgccccccgc ggctccccct ccggctcctc ctccggggag
241 acgccggggg cctggcccgg cccgcactca gactgctgct gcagccgccg ccgggggagt
301 cggaggcggt ggcggcgcca tgggcggcct ggcctctggg ggggatgtgg agccgggact
361 gcccgtcgag gtgcgcggct ccaacggggc cttctacaag ggctttgtga aggatgtcca
421 tgaagactct gtcaccatct tctttgaaaa caactggcag agtgagagac aaattccttt
481 tggggatgtc cggctaccac ctccagctga ctataataag gagatcacag aaggggatga
541 agtggaggtt tattctcgag ccaatgaaca ggaaccttgt ggctggtggc tggcccgggt
601 gcggatgatg aagggagatt tctatgtcat tgaatatgct gcctgtgatg ccacctacaa
661 tgaaattgtt accctggagc gacttcggcc agttaatccc aatccccttg caaccaaagg
721 cagcttcttc aaggttacca tggctgtgcc cgaggatctg agagaagcct gctccaatga
781 aaacgtccat aaagagttca agaaagccct gggagccaac tgcatctttc tcaacatcac
841 aaacagtgag ctcttcattc tgtcaaccac agaagcccct gtgaagcgag catctctgct
901 gggtgatatg catttccgaa gcctgcgcac caaactgcta cttatgtccc gcaatgaaga
961 agctaccaag cacctagaga caagcaagca gttggcagca gccttccaag aggagttcac
1021 agtgcgagag gacctgatgg gactggcaat tgggactcac ggtgccaaca tccagcaggc
1081 ccgaaaagta cctggggtga ccgccattga gttgggtgaa gagacctgca ctttccgcat
1141 ctatggggag actcccgagg cttgccgaca ggcccgaagc taccttgagt tttctgagga
1201 ctcagtgcaa gtgcccagga acctggttgg caaagtgatt ggaaagaacg ggaaagtgat
1261 ccaggagatt gtggataaat ctggtgtggt gagggttcga gtggaaggtg ataatgacaa
1321 gaagaacccc agggaggagg gaatggttcc cttcattttt gttggcaccc gagagaacat
1381 cagcaatgcc caggctttgc tggagtatca cctctcctac ctgcaggagg tagagcagct
1441 tcgcttggag aggctacaaa ttgatgagca gcttcggcag attgggctgg gctttcgccc
1501 tcctgggagt gggcggggca gcggtggcag cgacaaggct ggatatagca ctgatgagag
1561 ctcctcctcc tccctccatg cgactcgaac ctatgggggc agctatgggg gccgtggccg
1621 tggccggagg acaggcggtc ctgcctatgg ccccagctca gatgtgtcta cagcttcaga
1681 gactgagtca gagaagagag aggagcccaa ccgagctggg cctggcgaca gggatccccc
1741 aacccgaggg gaagaaagcc ggaggcggcc gactgggggc cggggtaggg gacccccacc
1801 tgccccccgg cccacttcga gatacaattc ttcatctatt agctcagtgc tgaaggatcc
1861 agacagtaat ccctacagcc tattggacac gtctgaacca gagcccccgg ttgattcaga
1921 acctggggaa ccccccccag caagtgccag gcgccgccgc tcccgccgcc gccgcactga
1981 tgaagacagg accgtcatgg atggaggcct ggaatcagat gggcccaaca tgacagagaa
2041 tggcctggaa gatgaatcaa gacctcaacg tcgtaatcgc agccgccgcc gccgtaaccg
2101 tggtaatcgg actgatggct ctatcagtgg agaccgccag ccagtgactg tggctgacta
2161 tatctcacga gcagagtctc agagccgcca gaggccaccc ctggaacgca ctaaaccctc
2221 agaagactct ctttcaggac agaagggtga ctctgtcagc aagcttccta agggcccctc
2281 ggagaatggg gagctctccg cccccttgga gttgggtagt atggtgaatg gggtttcata
2341 aaacctccaa cctgcacccc tcccttctcc atctcgcttg ctgcccaaca ccatggccct
2401 cacaggccca actgacctgc gctggagctg ctcttatcta ggggggaggg gggtggcaca
2461 gcagcttggg taccccccaa cctccaggag ctagtggagg ggtgtgtaac agggtcatac
2521 cccctccctc ttgtccaccc tacccccagg gtaaggggag cctctctcct tccccatcag
2581 actggatgtg cctttatcct ctaatgcccc aatctctctc tgaacacccc cattctccac
2641 ctgttggtgg ggggtgctcc tcgacccacc cagatttgac cgttcagggg gcctcccctg
2701 ctatccctcc tcccatcctg taccccccat ttctggggcc tcatcactgt ggaagacggg
2761 gatagtaaga gataagtggg tgggaggcac ggggaaggtt ttggagtaga accaggggtg
2821 tgtatgaagg ggggtgacaa ggtccccctg gggaggggac caaccttgtc tggtggatga
2881 gaaggcgtat ttatttttca ctgtacagta tttaaaaaaa aaaaaaaa
//