LOCUS BC019255 1580 bp mRNA linear HUM 16-DEC-2006
DEFINITION Homo sapiens phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoimidazole succinocarboxamide synthetase, mRNA
(cDNA clone MGC:1343 IMAGE:3533684), complete cds.
ACCESSION BC019255
VERSION BC019255.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1580)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1580)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 8 Row: k Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 17388802.
FEATURES Location/Qualifiers
source 1..1580
/db_xref="H-InvDB:HIT000038581"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1343 IMAGE:3533684"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1580
/gene="PAICS"
/gene_synonym="ADE2"
/gene_synonym="ADE2H1"
/gene_synonym="AIRC"
/gene_synonym="MGC1343"
/gene_synonym="MGC5024"
/db_xref="GeneID:10606"
/db_xref="HGNC:HGNC:8587"
/db_xref="MIM:172439"
CDS 162..1439
/gene="PAICS"
/gene_synonym="ADE2"
/gene_synonym="ADE2H1"
/gene_synonym="AIRC"
/gene_synonym="MGC1343"
/gene_synonym="MGC5024"
/codon_start=1
/product="phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoimidazole succinocarboxamide
synthetase"
/protein_id="AAH19255.1"
/db_xref="GeneID:10606"
/db_xref="HGNC:HGNC:8587"
/db_xref="MIM:172439"
/translation="MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNA
ARKNHLEGKAAISNKITSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRR
IATGSFLKRNPGVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQT
EVDIMSHATQAIFEILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWP
SGDRSQQKDKQSYRDLKEVTPEGLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTS
DLGHCEKIKKACGNFGIPCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNG
LGPVMSGNTAYPVISCPPLTPDWGVQDVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFG
LSNHLVWSKLRASILNTWISLKQADKKIRECNL"
BASE COUNT 493 a 302 c 380 g 405 t
ORIGIN
1 cccgtccggg ttaggcggct gtagcggagc tcgaaaagag tggcgcaggg tcgcgcggcc
61 ccgcctcctt ccccgcccag cgaagctctc tgaccacccc tcttttctag agttctgcct
121 cgcttcccgg cgcggtcgca gccctcagcc cacttaggat aatggcgaca gctgaggtac
181 tgaacattgg taaaaaatta tatgagggta aaacaaaaga agtctacgaa ttgttagaca
241 gtccaggaaa agtcctcctg cagtccaagg accagattac agcaggaaat gcagctagaa
301 aaaaccacct ggaaggaaaa gctgcaatct caaataaaat caccagttgt atttttcagt
361 tattacagga agcaggtatt aaaactgcct tcaccagaaa atgtggggag acagctttca
421 ttgcaccgca gtgtgaaatg attccaattg aatgggtttg cagaagaata gcaactggtt
481 cttttctcaa aagaaatcct ggtgtcaagg aaggatataa gttttaccca cctaaagtgg
541 agttgttttt caaggatgat gccaataatg acccacagtg gtctgaggaa cagctgattg
601 ctgcaaaatt ttgctttgct ggacttctta taggccagac tgaagtggat atcatgagtc
661 atgctacaca ggctatattt gaaatactgg agaaatcctg gttgccccag aattgtacac
721 tggttgatat gaagattgaa tttggtgttg atgtaaccac caaagaaatt gttcttgctg
781 atgttattga caatgattcc tggagactct ggccatcagg agatcgaagc caacagaaag
841 acaaacagtc ttatcgggac ctcaaagaag taactcctga agggctccaa atggtaaaga
901 aaaactttga gtgggttgca gagagagtag agttgctttt gaaatcagaa agtcagtgca
961 gggttgtagt gttgatgggc tctacttctg atcttggtca ctgtgaaaaa atcaagaagg
1021 cctgtggaaa ttttggcatt ccatgtgaac ttcgagtaac atctgcgcat aaaggaccag
1081 atgaaactct gaggattaaa gctgagtatg aaggggatgg cattcctact gtatttgtgg
1141 cagtggcagg cagaagtaat ggtttgggac cagtgatgtc tgggaacact gcatatccag
1201 ttatcagctg tcctcccctc acaccagact ggggagttca ggatgtgtgg tcttctcttc
1261 gactacccag tggtcttggc tgttcaaccg tactttctcc agaaggatca gctcaatttg
1321 ctgctcagat atttgggtta agcaaccatt tggtatggag caaactgcga gcaagcattt
1381 tgaacacatg gatttccttg aagcaggctg acaagaaaat cagagaatgt aatttataag
1441 aaagaatgcc attgaatttt ttaggggaaa aactacaaat ttctaattta gctgaaggaa
1501 aatcaagcaa gatgaaaagg taattttaaa ttagagaaca caaataaaat gtattagtga
1561 ataaaaaaaa aaaaaaaaaa
//