LOCUS BC018986 2592 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD), mRNA
(cDNA clone MGC:20092 IMAGE:3638799), complete cds.
ACCESSION BC018986
VERSION BC018986.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2592)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2592)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC018986.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 28 Row: d Column: 7.
FEATURES Location/Qualifiers
source 1..2592
/db_xref="H-InvDB:HIT000038494"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20092 IMAGE:3638799"
/tissue_type="Pancreas, adenocarcinoma"
/clone_lib="NIH_MGC_39"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2592
/gene="HPGD"
/gene_synonym="15-PGDH"
/gene_synonym="PGDH"
/gene_synonym="PGDH1"
/db_xref="GeneID:3248"
/db_xref="HGNC:HGNC:5154"
/db_xref="MIM:601688"
CDS 10..810
/gene="HPGD"
/gene_synonym="15-PGDH"
/gene_synonym="PGDH"
/gene_synonym="PGDH1"
/codon_start=1
/product="hydroxyprostaglandin dehydrogenase 15-(NAD)"
/protein_id="AAH18986.1"
/db_xref="GeneID:3248"
/db_xref="HGNC:HGNC:5154"
/db_xref="MIM:601688"
/translation="MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQ
CKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEK
TLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVG
FTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYG
ILDPPLIANGLITLIEDDALNGAIMKITTSKGIHFQDYDTTPFQAKTQ"
BASE COUNT 907 a 432 c 444 g 809 t
ORIGIN
1 ggctgcacca tgcacgtgaa cggcaaagtg gcgctggtga ccggcgcggc tcagggcata
61 ggcagagcct ttgcagaggc gctgctgctt aagggcgcca aggtagcgct ggtggattgg
121 aatcttgaag caggtgtaca gtgtaaagct gccctggatg agcagtttga acctcagaag
181 actctgttca tccagtgcga tgtggctgac cagcaacaac tgagagacac ttttagaaaa
241 gttgtagacc actttggaag actggacatt ttggtcaata atgctggagt gaataatgag
301 aaaaactggg aaaaaactct gcaaattaat ttggtttctg ttatcagtgg aacctatctt
361 ggtttggatt acatgagtaa gcaaaatgga ggtgaaggcg gcatcattat caatatgtca
421 tctttagcag gactcatgcc cgttgcacag cagccggttt attgtgcttc aaagcatggc
481 atagttggat tcacacgctc agcagcgttg gctgctaatc ttatgaacag tggtgtgaga
541 ctgaatgcca tttgtccagg ctttgttaac acagccatcc ttgaatcaat tgaaaaagaa
601 gaaaacatgg gacaatatat agaatataag gatcatatca aggatatgat taaatactat
661 ggaattttgg acccaccatt gattgccaat ggattgataa cactcattga agatgatgct
721 ttaaatggtg ctattatgaa gatcacaact tctaagggaa ttcattttca agactatgat
781 acaactccat ttcaagcaaa aacccaatga acagcttatg tgttagccat agctgaaaat
841 aagcacaaat agcttatatt cagatcctat cttcatttga atatagcttt taaatgaaat
901 gttacagttt gaagttttcc ttcatgcact tggtgataaa cgttttctaa atttttagtt
961 aagtatatgg ataaaaagtt atgaactatt aaaaatgtga tgtggaccaa aggctaggtt
1021 gtaatcttga tagtctaaaa aatgatcaaa acaaatgatt ttcaaggaat attcaatatt
1081 ctgcctttca gaaagtgtat ttatatctgt gcttcataaa tattaatgtt cttcagaaca
1141 tcattttaaa ggagatactt gaattgttat ttaaatcaaa ccagatgtaa aacactcaca
1201 tacaagttca tactttaaaa gaggaaagct acttaacaat gacaaatatt tcacaataat
1261 aatttttact tatataccat ctttcaactg aacatttcag ttcttccaag agcttcttag
1321 agtagtatat tttgggggca gtcaaggaat aaactacagt gtaaacatat cccagatgaa
1381 aactgctgta tggaaaaatg acagaaagta actgattgac actgttgatt cacagttcag
1441 cctcctatct gggaaagaca tttctttcct ctgctcactt taagaacttt taccgactcc
1501 aaaaatctca ggaattaaac ttttaacagt tacagcaata aagaatagtt agtactccaa
1561 aaatattata tttaagatgc tcaacaagaa aaaaatgcaa atgtaatatt tttttcaaat
1621 tacttcttta ttgacttgtc caaatttcaa aagtgcctac ccttcaataa aactttttta
1681 ttctgatctc cataaattac ttagtcttct atgtatagct atcaaggaaa taaaaccaat
1741 tttgccacag ccacaactgt aaatgttttt gtacccatgc tgaaactcat aacaacacag
1801 acataaaaat agctgtgagg ttttgctttt tttgttgtca gctatcttaa gaatcattaa
1861 atacacctgc tttgggtaaa actctttgca agcagtaatt aacactagta acagtgaaag
1921 cacaagattt ccaaatcagt cgttttctca aaaaaatatc gtataagtga ctcatcctgt
1981 ctgctaactc cagacctccc agcttgaagc caaatctttc catgtgagat tgatatggat
2041 ttcctagaag tactggaatg ttgtcatatc ttgccctatt ttaattctgc tatagaaaac
2101 aattgccttc acttttaagg agtaatttga atattaataa ctctggtcta gattttcata
2161 taatgtatta aagacaaagt agtgaacatc aatgaacatc tgatagagat aaactgtaat
2221 caggcataag cttgtttgta tgttctggca gtgactaatc agtaaatgat gtcggtttgc
2281 ccagtatcac ttatcttctg tatttttcct ctgtcgtgta aatagtataa ccttttcatt
2341 tatggacaat tttttggact agtagccttc aatatacatt ctgctttgaa ttaatttttt
2401 caaatcaata aattatgtag acatttaaaa tcaaatatca agtagaattg aaaaatgtga
2461 gttacataag ttaaaaactt actttaaatc ttaccttcta taggtagctc taaataaatt
2521 catatggtta tatggcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2581 aaaaaaaaaa aa
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