LOCUS BC018650 2811 bp mRNA linear HUM 09-JUN-2008 DEFINITION Homo sapiens sphingosine-1-phosphate receptor 1, mRNA (cDNA clone MGC:22155 IMAGE:4071217), complete cds. ACCESSION BC018650 VERSION BC018650.1 KEYWORDS MGC. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 2811) AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A. CONSRTM Mammalian Gene Collection Program Team TITLE Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002) PUBMED 12477932 REFERENCE 2 (bases 1 to 2811) CONSRTM NIH MGC Project TITLE Direct Submission JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda, MD 20892-2590, USA REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov COMMENT Contact: MGC help desk Email: cgapbs-r@mail.nih.gov Tissue Procurement: CLONTECH cDNA Library Preparation: CLONTECH Laboratories, Inc. cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) DNA Sequencing by: Institute for Systems Biology http://www.systemsbiology.org contact: amadan@systemsbiology.org Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting Clone distribution: MGC clone distribution information can be found through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov Series: IRAL Plate: 32 Row: n Column: 14 This clone was selected for full length sequencing because it passed the following selection criteria: matched mRNA gi: 13027635. FEATURES Location/Qualifiers source 1..2811 /db_xref="H-InvDB:HIT000038386" /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /clone="MGC:22155 IMAGE:4071217" /tissue_type="Lung" /clone_lib="NIH_MGC_77" /lab_host="DH10B" /note="Vector: pDNR-LIB" gene 1..2811 /gene="S1PR1" /gene_synonym="CHEDG1" /gene_synonym="D1S3362" /gene_synonym="ECGF1" /gene_synonym="EDG-1" /gene_synonym="S1P1" /db_xref="GeneID:1901" /db_xref="HGNC:HGNC:3165" /db_xref="MIM:601974" CDS 249..1397 /gene="S1PR1" /gene_synonym="CHEDG1" /gene_synonym="D1S3362" /gene_synonym="ECGF1" /gene_synonym="EDG-1" /gene_synonym="S1P1" /codon_start=1 /product="sphingosine-1-phosphate receptor 1" /protein_id="AAH18650.1" /db_xref="GeneID:1901" /db_xref="HGNC:HGNC:3165" /db_xref="MIM:601974" /translation="MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENS IKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANL LLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRL FLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIV ILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILL LLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSG DSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS" BASE COUNT 707 a 707 c 629 g 768 t ORIGIN 1 ggggagtcgg gggcagcagc aagatgcgaa gcgagccgta cagatcccgg gctctccgaa 61 cgcaacttcg ccctgcttga gcgaggctgc ggtttccgag gccctctcca gccaaggaaa 121 agctacacaa aaagcctgga tcactcatcg aaccacccct gaagccagtg aaggctctct 181 cgcctcgccc tctagcgttc gtctggagta gcgccacccc ggcttcctgg ggacacaggt 241 ttggcaccat ggggcccacc agcgtcccgc tggtcaaggc ccaccgcagc tcggtctctg 301 actacgtcaa ctatgatatc atcgtccggc attacaacta cacgggaaag ctgaatatca 361 gcgcggacaa ggagaacagc attaaactga cctcggtggt gttcattctc atctgctgct 421 ttatcatcct ggagaacatc tttgtcttgc tgaccatttg gaaaaccaag aaattccacc 481 gacccatgta ctattttatt ggcaatctgg ccctctcaga cctgttggca ggagtagcct 541 acacagctaa cctgctcttg tctggggcca ccacctacaa gctcactccc gcccagtggt 601 ttctgcggga agggagtatg tttgtggccc tgtcagcctc cgtgttcagt ctcctcgcca 661 tcgccattga gcgctatatc acaatgctga aaatgaaact ccacaacggg agcaataact 721 tccgcctctt cctgctaatc agcgcctgct gggtcatctc cctcatcctg ggtggcctgc 781 ctatcatggg ctggaactgc atcagtgcgc tgtccagctg ctccaccgtg ctgccgctct 841 accacaagca ctatatcctc ttctgcacca cggtcttcac tctgcttctg ctctccatcg 901 tcattctgta ctgcagaatc tactccttgg tcaggactcg gagccgccgc ctgacgttcc 961 gcaagaacat ttccaaggcc agccgcagct ctgagaagtc gctggcgctg ctcaagaccg 1021 taattatcgt cctgagcgtc ttcatcgcct gctgggcacc gctcttcatc ctgctcctgc 1081 tggatgtggg ctgcaaggtg aagacctgtg acatcctctt cagagcggag tacttcctgg 1141 tgttagctgt gctcaactcc ggcaccaacc ccatcattta cactctgacc aacaaggaga 1201 tgcgtcgggc cttcatccgg atcatgtcct gctgcaagtg cccgagcgga gactctgctg 1261 gcaaattcaa gcgacccatc atcgccggca tggaattcag ccgcagcaaa tcggacaatt 1321 cctcccaccc ccagaaagac gaaggggaca acccagagac cattatgtct tctggaaacg 1381 tcaactcttc ttcctagaac tggaagctgt ccacccaccg gaagcgctct ttacttggtc 1441 gctggccacc ccagtgtttg gaaaaaaatc tctgggcttc gactgctgcc agggaggagc 1501 tgctgcaagc cagagggagg aagggggaga atacgaacag cctggtggtg tcgggtgttg 1561 gtgggtagag ttagttcctg tgaacaatgc actgggaagg gtggagatca ggtcccggcc 1621 tggaatatat tttctacccc cctggagctt tgattttgca ctgagccaaa ggtctagcat 1681 tgtcaagctc ctaaagggtt catttggccc ctcctcaaag actaatgtcc ccatgtgaaa 1741 gcgtctcttt gtctggagct ttgaggagat gttttccttc actttagttt caaacccaag 1801 tgagtgtgtg cacttctgct tctttaggga tgccctgtac atcccacacc ccaccctccc 1861 ttcccttcat acccctcctc aacgttcttt tactttatac tttaactacc tgagagttat 1921 cagagctggg gttgtggaat gatcgatcat ctatagcaaa taggctatgt tgagtacgta 1981 ggctgtggga agatgaagat ggtttggagg tgtaaaacaa tgtccttcgc tgaggccaaa 2041 gtttccatgt aagcgggatc cgttttttgg aatttggttg aagtcacttt gatttcttta 2101 aaaaacatct tttcaatgaa atgtgttacc atttcatatc cattgaagcc gaaatctgca 2161 taaggaagcc cactttatct aaatgatatt agccaggatc cttggtgtcc taggagaaac 2221 agacaagcaa aacaaagtga aaaccgaatg gattaacttt tgcaaaccaa gggagatttc 2281 ttagcaaatg agtctaacaa atatgacatc tgtctttggc acttttgttg atgtttattt 2341 cagaatgttg tgtgattcat ttcaagcaac aacatggttg tattttgttg tgttaaaagt 2401 acttttcttg atttttgaat gtatttgttt cagcagaagt cattttattg gatttttcta 2461 acccgtgtta acaccattga atgtgtattt cttaagaaaa taccaccctc ttgtgccctt 2521 aaaagcatta ctttaactgg tagggaacgc cagaaacttt tcagtccagc tattcattag 2581 atagtaattg aagatatgta taaatattac aaagaataaa aatatattac tgtctcttta 2641 gtatggtttt cagtgcaatt aaaccgagag atgtcttgtt tttttaaaaa gaatagtatt 2701 taataggttt ctgacttttg tggatcattt tgcacatagc tttatcaact tttaaacatt 2761 aataaactga tttttttaag gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a //