LOCUS BC018636 2556 bp mRNA linear HUM 19-MAR-2007
DEFINITION Homo sapiens plasminogen activator, tissue, mRNA (cDNA clone
MGC:15288 IMAGE:3637273), complete cds.
ACCESSION BC018636
VERSION BC018636.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2556)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2556)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC018636.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 24 Row: l Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 14702165.
FEATURES Location/Qualifiers
source 1..2556
/db_xref="H-InvDB:HIT000038377"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:15288 IMAGE:3637273"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2556
/gene="PLAT"
/gene_synonym="T-PA"
/gene_synonym="TPA"
/db_xref="GeneID:5327"
/db_xref="HGNC:HGNC:9051"
/db_xref="MIM:173370"
CDS 84..1772
/gene="PLAT"
/gene_synonym="T-PA"
/gene_synonym="TPA"
/codon_start=1
/product="plasminogen activator, tissue"
/protein_id="AAH18636.3"
/db_xref="GeneID:5327"
/db_xref="HGNC:HGNC:9051"
/db_xref="MIM:173370"
/translation="MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDE
KTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALY
FSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKP
YSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFG
NGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKP
WCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRR
SPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKY
IVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYG
KHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDA
CQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP"
BASE COUNT 644 a 688 c 684 g 540 t
ORIGIN
1 caggagtcca gggctggaga gaaaacctct gcgaggaaag ggaaggagca agccgtgaat
61 ttaagggacg ctgtgaagca atcatggatg caatgaagag agggctctgc tgtgtgctgc
121 tgctgtgtgg agcagtcttc gtttcgccca gccaggaaat ccatgcccga ttcagaagag
181 gagccagatc ttaccaagtg atctgcagag atgaaaaaac gcagatgata taccagcaac
241 atcagtcatg gctgcgccct gtgctcagaa gcaaccgggt ggaatattgc tggtgcaaca
301 gtggcagggc acagtgccac tcagtgcctg tcaaaagttg cagcgagcca aggtgtttca
361 acgggggcac ctgccagcag gccctgtact tctcagattt cgtgtgccag tgccccgaag
421 gatttgctgg gaagtgctgt gaaatagata ccagggccac gtgctacgag gaccagggca
481 tcagctacag gggcacgtgg agcacagcgg agagtggcgc cgagtgcacc aactggaaca
541 gcagcgcgtt ggcccagaag ccctacagcg ggcggaggcc agacgccatc aggctgggcc
601 tggggaacca caactactgc agaaacccag atcgagactc aaagccctgg tgctacgtct
661 ttaaggcggg gaagtacagc tcagagttct gcagcacccc tgcctgctct gagggaaaca
721 gtgactgcta ctttgggaat gggtcagcct accgtggcac gcacagcctc accgagtcgg
781 gtgcctcctg cctcccgtgg aattccatga tcctgatagg caaggtttac acagcacaga
841 accccagtgc ccaggcactg ggcctgggca aacataatta ctgccggaat cctgatgggg
901 atgccaagcc ctggtgccac gtgctgaaga accgcaggct gacgtgggag tactgtgatg
961 tgccctcctg ctccacctgc ggcctgagac agtacagcca gcctcagttt cgcatcaaag
1021 gagggctctt cgccgacatc gcctcccacc cctggcaggc tgccatcttt gccaagcaca
1081 ggaggtcgcc cggagagcgg ttcctgtgcg ggggcatact catcagctcc tgctggattc
1141 tctctgccgc ccactgcttc caggagaggt ttccgcccca ccacctgacg gtgatcttgg
1201 gcagaacata ccgggtggtc cctggcgagg aggagcagaa atttgaagtc gaaaaataca
1261 ttgtccataa ggaattcgat gatgacactt acgacaatga cattgcgctg ctgcagctga
1321 aatcggattc gtcccgctgt gcccaggaga gcagcgtggt ccgcactgtg tgccttcccc
1381 cggcggacct gcagctgccg gactggacgg agtgtgagct ctccggctac ggcaagcatg
1441 aggccttgtc ccctttctat tcggagcggc tgaaggaggc tcatgtcaga ctgtacccat
1501 ccagccgctg cacatcacaa catttactta acagaacagt caccgacaac atgctgtgtg
1561 ctggagacac tcggagcggc gggccccagg caaacttgca cgacgcctgc cagggcgatt
1621 cgggaggccc cctggtgtgt ctgaacgatg gccgcatgac tttggtgggc atcatcagct
1681 ggggcctggg ctgtggacag aaggatgtcc cgggtgtgta caccaaggtt accaactacc
1741 tagactggat tcgtgacaac atgcgaccgt gaccaggaac acccgactcc tcaaaagcaa
1801 atgagatccc gcctcttctt cttcagaaga cactgcaaag gcgcagtgct tctctacaga
1861 cttctccaga cccaccacac cgcagaagcg ggacgagacc ctacaggaga gggaagagtg
1921 cattttccca gatacttccc attttggaag ttttcaggac ttggtctgat ttcaggatac
1981 tctgtcagat gggaagacat gaatgcacac tagcctctcc aggaatgcct cctccctggg
2041 cagaaagtgg ccatgccacc ctgttttcag ctaaagccca acctcctgac ctgtcaccgt
2101 gagcagcttt ggaaacagga ccacaaaaat gaaagcatgt ctcaatagta aaagataaca
2161 agatctttca ggaaagacgg attgcattag aaatagacag tatatttata gtcacaagag
2221 cccagcaggg cctcaaagtt ggggcaggct ggctggcccg tcatgttcct caaaagcacc
2281 cttgacgtca agtctccttc ccctttcccc actccctggc tctcagaagg tattcctttt
2341 gtgtacagtg tgtaaagtgt aaatcctttt tctttataaa ctttagagta gcatgagaga
2401 attgtatcat ttgaacaact aggcttcagc atatttatag caatccatgt tagtttttac
2461 tttctgttgc cacaaccctg ttttatactg tacttaataa attcagatat atttttcaca
2521 gtttttccaa aaaaaaaaaa aaaaaaaaaa aaaaaa
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