LOCUS BC018214 1758 bp mRNA linear HUM 16-SEP-2003
DEFINITION Homo sapiens DNA (cytosine-5-)-methyltransferase 3 alpha, mRNA
(cDNA clone IMAGE:3862699), partial cds.
ACCESSION BC018214
VERSION BC018214.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1758)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1758)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 21 Row: h Column: 23.
FEATURES Location/Qualifiers
source 1..1758
/db_xref="H-InvDB:HIT000089588"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3862699"
/tissue_type="Ovary, adenocarcinoma"
/clone_lib="NIH_MGC_66"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..1758
/gene="DNMT3A"
/gene_synonym="DNMT3A2"
/gene_synonym="M.HsaIIIA"
/db_xref="GeneID:1788"
/db_xref="MIM:602769"
CDS <1..859
/gene="DNMT3A"
/gene_synonym="DNMT3A2"
/gene_synonym="M.HsaIIIA"
/codon_start=2
/product="DNMT3A protein"
/protein_id="AAH18214.1"
/db_xref="GeneID:1788"
/db_xref="MIM:602769"
/translation="AEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSIT
VGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGR
LFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSA
AHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKD
QHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFA
PLKEYFACV"
misc_feature 14..505
/gene="DNMT3A"
/gene_synonym="DNMT3A2"
/gene_synonym="M.HsaIIIA"
/note="Dcm; Region: Site-specific DNA methylase [DNA
replication, recombination, and repair]"
/db_xref="CDD:COG0270"
BASE COUNT 513 a 376 c 428 g 441 t
ORIGIN
1 agctgagaag aggaagccca tccgggtgct gtctctcttt gatggaatcg ctacagggct
61 cctggtgctg aaggacttgg gcattcaggt ggaccgctac attgcctcgg aggtgtgtga
121 ggactccatc acggtgggca tggtgcggca ccaggggaag atcatgtacg tcggggacgt
181 ccgcagcgtc acacagaagc atatccagga gtggggccca ttcgatctgg tgattggggg
241 cagtccctgc aatgacctct ccatcgtcaa ccctgctcgc aagggcctct acgagggcac
301 tggccggctc ttctttgagt tctaccgcct cctgcatgat gcgcggccca aggagggaga
361 tgatcgcccc ttcttctggc tctttgagaa tgtggtggcc atgggcgtta gtgacaagag
421 ggacatctcg cgatttctcg agtccaaccc tgtgatgatt gatgccaaag aagtgtcagc
481 tgcacacagg gcccgctact tctggggtaa ccttcccggt atgaacaggc cgttggcatc
541 cactgtgaat gataagctgg agctgcagga gtgtctggag catggcagga tagccaagtt
601 cagcaaagtg aggaccatta ctacgaggtc aaactccata aagcagggca aagaccagca
661 ttttcctgtc ttcatgaatg agaaagagga catcttatgg tgcactgaaa tggaaagggt
721 atttggtttc ccagtccact atactgacgt ctccaacatg agccgcttgg cgaggcagag
781 actgctgggc cggtcatgga gcgtgccagt catccgccac ctcttcgctc cgctgaagga
841 gtattttgcg tgtgtgtaag ggacatgggg gcaaactgag gtagcgacac aaagttaaac
901 aaacaaacaa aaaacacaaa acataataaa acaccaagaa catgaggatg gagagaagta
961 tcagcaccca gaagagaaaa aggaatttaa aacaaaaacc acagaggcgg aaataccgga
1021 gggctttgcc ttgcgaaaag ggttggacat catctcctga tttttcaatg ttattcttca
1081 gtcctattta aaaacaaaac caagctccct tcccttcctc ccccttccct tttttttcgg
1141 tcagaccttt tattttctac tcttttcaga ggggttttct gtttgtttgg gttttgtttc
1201 ttgctgtgac tgaaacaaga aggttattgc agcaaaaatc agtaacaaaa aatagtaaca
1261 ataccttgca gaggaaaggt gggagagagg aaaaaaggaa attctataga aatctatata
1321 ttgggttgtt tttttttttg ttttttgttt tttttttttg ggtttttttt tttactatat
1381 atcttttttt tgttgtctct agcctgatca gataggagca caagcagggg acggaaagag
1441 agagacactc aggcggcagc attccctccc agccactgag ctgtcgtgcc agcaccattc
1501 ctggtcacgc aaaacagaac ccagttagca gcagggagac gagaacacca cacaagacat
1561 ttttctacag tatttcaggt gcctaccaca caggaaacct tgaagaaaat cagtttctag
1621 aagccgctgt tacctcttgt ttacagttta tatatatatg atagatatga gatatatata
1681 taaaaggtac tgttaactac tgtaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1741 aaaaaaaaaa aaaaaaaa
//