LOCUS BC018207 1871 bp mRNA linear HUM 06-OCT-2003
DEFINITION Homo sapiens glutamic-pyruvate transaminase (alanine
aminotransferase), mRNA (cDNA clone MGC:17068 IMAGE:4179699),
complete cds.
ACCESSION BC018207
VERSION BC018207.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1871)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1871)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 12 Row: j Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4885350.
FEATURES Location/Qualifiers
source 1..1871
/db_xref="H-InvDB:HIT000038314"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17068 IMAGE:4179699"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1871
/gene="GPT"
/gene_synonym="AAT1"
/gene_synonym="ALT1"
/gene_synonym="GPT1"
/db_xref="GeneID:2875"
/db_xref="MIM:138200"
CDS 158..1648
/gene="GPT"
/gene_synonym="AAT1"
/gene_synonym="ALT1"
/gene_synonym="GPT1"
/codon_start=1
/product="GPT protein"
/protein_id="AAH18207.1"
/db_xref="GeneID:2875"
/db_xref="MIM:138200"
/translation="MASSTGDRSQAVRHGLRAKVLTLDGMNPRVRRVEYAVRGPIVQR
ALELEQELRQGVKKPFTEVIRANIGDAQAMGQRPITFLRQVLALCVNPDLLSSPNFPD
DAKKRAERILQACGGHSLGAYSVSSGIQLIREDVARYIERRDGGIPADPNNVFLSTGA
SDAIVTVLKLLVAGEGHTRTGVLIPIPQYPLYSATLAELGAVQVDYYLDEERAWALDV
AELHRALGQARDHCRPRALCVINPGNPTGQVQTRECIEAVIRFAFEERLFLLADEVYQ
DNVYAAGSQFHSFKKVLMEMGPPYAGQQELASFHSTSKGYMGECGFRGGYVEVVNMDA
AVQQQMLKLMSVRLCPPVPGQALLDLVVSPPAPTDPSFAQFQAEKQAVLAELAAKAKL
TEQVFNEAPGISCNPVQGAMYSFPRVQLPPRAVERAQELGLAPDMFFCLRLLEETGIC
VVPGSGFGQREGTYHFRMTILPPLEKLRLLLEKLSRFHAKFTLEYS"
misc_feature 239..1564
/gene="GPT"
/gene_synonym="AAT1"
/gene_synonym="ALT1"
/gene_synonym="GPT1"
/note="COG0436; Region: Aspartate/tyrosine/aromatic
aminotransferase [Amino acid transport and metabolism]"
/db_xref="CDD:COG0436"
BASE COUNT 350 a 565 c 638 g 318 t
ORIGIN
1 agggctgcca cttggactcc cttgccaggg ggcgggcagg ggctggctct gcctggggcc
61 aggcccatgt taacctgtgc cccggcctgg gggccagagg ggcaggcctg cgcacgggga
121 ggctgttgtg gcagcggaac agagacgtgc acgagtcatg gcctcgagca caggtgaccg
181 gagccaggcg gtgaggcatg gactgagggc gaaggtgctg acgctggacg gcatgaaccc
241 gcgtgtgcgg agagtggagt acgcagtgcg tggccccata gtgcagcgag ccttggagct
301 ggagcaggag ctgcgccagg gtgtgaagaa gcctttcacc gaggtcatcc gtgccaacat
361 cggggacgca caggctatgg ggcagaggcc catcaccttc ctgcgccagg tcttggccct
421 ctgtgttaac cctgatcttc tgagcagccc caacttccct gacgatgcca agaaaagggc
481 ggagcgcatc ttgcaggcgt gtgggggcca cagtctgggg gcctacagcg tcagctccgg
541 catccagctg atccgggagg acgtggcgcg gtacattgag aggcgtgacg gaggcatccc
601 tgcggacccc aacaacgtct tcctgtccac aggggccagc gatgccatcg tgacggtgct
661 gaagctgctg gtggccggcg agggccacac acgcacgggt gtgctcatcc ccatccccca
721 gtacccactc tactcggcca cgctggcaga gctgggcgca gtgcaggtgg attactacct
781 ggacgaggag cgtgcctggg cgctggacgt ggccgagctt caccgtgcac tgggccaggc
841 gcgtgaccac tgccgccctc gtgcgctctg tgtcatcaac cctggcaacc ccaccgggca
901 ggtgcagacc cgcgagtgca tcgaggccgt gatccgcttc gccttcgaag agcggctctt
961 tctgctggcg gacgaggtgt accaggacaa cgtgtacgcc gcgggttcgc agttccactc
1021 attcaagaag gtgctcatgg agatggggcc gccctacgcc gggcagcagg agcttgcctc
1081 cttccactcc acctccaagg gctacatggg cgagtgcggg ttccgcggcg gctatgtgga
1141 ggtggtgaac atggacgctg cagtgcagca gcagatgctg aagctgatga gtgtgcggct
1201 gtgcccgccg gtgccaggac aggccctgct ggacctggtg gtcagcccgc ccgcgcccac
1261 cgacccctcc tttgcgcagt tccaggctga gaagcaggca gtgctggcag agctggcggc
1321 caaggccaag ctcaccgagc aggtcttcaa tgaggctcct ggcatcagct gcaacccagt
1381 gcagggcgcc atgtactcct tcccgcgcgt gcagctgccc ccgcgggcgg tggagcgcgc
1441 tcaggagctg ggcctggccc ccgatatgtt cttctgcctg cgcctcctgg aggagaccgg
1501 catctgcgtg gtgccaggga gcggctttgg gcagcgggaa ggcacctacc acttccggat
1561 gaccattctg ccccccttgg agaaactgcg gctgctgctg gagaagctga gcaggttcca
1621 tgccaagttc accctcgagt actcctgagc accccagctg gggccaggct gggtcgccct
1681 ggactgtgtg ctcaggagcc ctgggaggct ctggagccca ctgtacttgc tcttgatgcc
1741 tggcggggtg gggtgggggg ggtgctgggc ccctgcctct ctgcaggtcc ctaataaagc
1801 tgtgtggcag tctgactcca ggaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1861 aaaaaaaaaa a
//