LOCUS BC018118 3372 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens Rho GTPase activating protein 1, mRNA (cDNA clone
MGC:8993 IMAGE:3896574), complete cds.
ACCESSION BC018118
VERSION BC018118.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3372)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3372)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 14 Row: i Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 19923243.
FEATURES Location/Qualifiers
source 1..3372
/db_xref="H-InvDB:HIT000038276"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8993 IMAGE:3896574"
/tissue_type="Pancreas, epithelioid carcinoma"
/clone_lib="NIH_MGC_70"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3372
/gene="ARHGAP1"
/gene_synonym="CDC42GAP"
/gene_synonym="p50rhoGAP"
/gene_synonym="RHOGAP"
/gene_synonym="RHOGAP1"
/db_xref="GeneID:392"
/db_xref="HGNC:HGNC:673"
/db_xref="MIM:602732"
CDS 70..1389
/gene="ARHGAP1"
/gene_synonym="CDC42GAP"
/gene_synonym="p50rhoGAP"
/gene_synonym="RHOGAP"
/gene_synonym="RHOGAP1"
/codon_start=1
/product="Rho GTPase activating protein 1"
/protein_id="AAH18118.1"
/db_xref="GeneID:392"
/db_xref="HGNC:HGNC:673"
/db_xref="MIM:602732"
/translation="MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPSDEMPDFPKS
DDSKSSSPELVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHS
KLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYI
VHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLK
STQKSPATAPKPMPPRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALT
TEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDL
YPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNL
AVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDPSGL"
BASE COUNT 683 a 1061 c 854 g 774 t
ORIGIN
1 gggagcagtg cccgagcgcg gtttctctta aggttctgca gggcaaggct gtctgggaca
61 ggcttggcca tggatccgct ctcagagctg caggatgatc tgaccttgga tgacaccagc
121 gaggctctga accagctgaa gctggcctcc atcgatgaga agaactggcc ctcggatgaa
181 atgcctgact tccccaagtc agatgactcc aaaagcagct ccccggaact tgtcacacac
241 ctgaagtggg atgacccata ctatgacatc gcccggcacc agatcgtgga ggtggcagga
301 gatgacaagt atgggcggaa gatcattgtg tttagtgcct gtcgaatgcc ccccagccac
361 cagctcgacc acagcaagct cctggggtac ctgaagcaca ccctggacca gtacgtggag
421 agtgactaca cacttctgta tctgcaccac ggcctgacca gcgacaacaa gccctccctc
481 agctggctcc gtgatgccta ccgggagttt gaccgcaagt acaagaagaa catcaaggcc
541 ttgtacatcg tgcatccaac catgttcatc aaaactctgc tcatcctctt caagcccctc
601 atcagcttca agttcgggca gaagatcttc tatgtgaatt acctgagcga gctgagcgag
661 cacgtgaagc tggagcagct ggggatccct cgccaagtgc tcaaatatga cgacttcctg
721 aaatccacac agaagagccc cgcgacagcc cccaagccca tgcccccacg gccccccctg
781 cccaaccagc agtttggagt ctcgctgcag cacctccagg agaagaatcc agagcaggag
841 cccattccca ttgtactcag ggagactgtt gcctacttac aggcccacgc tctcaccacc
901 gagggcatct tccggaggtc ggccaacacc caagtggtcc gggaagtgca gcagaagtac
961 aacatggggc tgcctgtgga tttcgaccag tacaatgagc tgcacctgcc agcagtcatc
1021 ctcaagacct tcctccggga gcttcctgag cccctgctca cctttgacct ctacccccat
1081 gtggtgggct tcctcaacat tgatgaaagc cagagggtgc cagcgacact gcaggtcctc
1141 cagacgctgc ccgaggagaa ctaccaggtg cttcgtttcc tgactgcttt cctggtgcag
1201 atttctgcac acagtgacca gaacaagatg accaacacta acctggctgt tgttttcggc
1261 cctaacctgc tgtgggccaa ggatgcggcc atcaccctca aggccattaa tcccatcaac
1321 accttcacca agttccttct ggatcaccaa ggggagctgt tcccaagccc ggaccccagc
1381 gggctctgaa cctggcccct gccccaccag ccccttctct ggtagcccgg gtttggactc
1441 ttcctcctgg catcaggggc catgaagccc cctggagaga gatgttggag ccacccatca
1501 ggcatgctct cccccacctc tgtccagccc gcctcacggc cctggcggcc tcgctgttac
1561 cagaagacgt ttttctctgc cttacacttc tcactgcctc tctggacacc gggcttttgc
1621 tgggctctcc agagctgggc ttggctcttc cagctggaga aggactgagc cccagtaacc
1681 cctttcctgc tttttcctgc ctctgtttcc ctagcaagtg tggatgaatc aaatgactgc
1741 cggctgggct ggtagcaggg gccagtcctc ccctcttgat tgctgggaat gagcagctga
1801 gctctttggt gtggacaccg ccccaagctg aggtgcctcc ctatctggta ggctgccctg
1861 ctttgcagaa gccccactgc atgaaggcct gagtgcaagc acccttgctc ctgtactgcc
1921 cccagcagcg cagtctgggg tatttcccct gctgaggagt gacagggctg gagactgtgt
1981 ctgctttctg cctcctcttc cacacatcct gggtcagcct ttcccaagtg atactgcccc
2041 tggggtgtcc taaccccttg gttgtgcagg gactggtagc ttggatgaca tggctcagag
2101 tcccagcatc cacttgaaac ctccctctcc acctccccgc ccccgagagc tacagcgtgt
2161 gatggaatca gtgaccggcc aggttagcct ctcccctctt ggcctccttt cccacacggg
2221 cagatcatca gccttcatgt tcttgtggac ctgtctgtta cggagtcaca ctggcccctg
2281 ccccagccag aggtgactca gtgcctcagg atcttatggc tccttcctcc agctggggga
2341 ctcttaaagg ggctggggta gagactaaga gtgcccgtag gaggggcaga gattgtgctg
2401 ataggtcagt ccagataggt gggttctagc aatttcccca ggggattaag gggctctagg
2461 gccacctttt tttttttttt tctgagatgg agtctcgctc tgtcaccagg ctggagtgca
2521 gtggcgcgat ctcggcacac ctccgccttc tgggttcaag caattctcct gcctcagcct
2581 cctgagtagc tgggactata ggtgcatgcc accatgccca gctaattttt gtatttttag
2641 tagagacggg gtttcaccat gttggccagg atggtctcga tctcctgacc tcatgatcca
2701 cccacctcgg cctcccaaag tgctgggatt ccaggcgtga gccactgcgc ccggccagcc
2761 ctgttgtctt tcaaagaacc tcggccccag tgatggctga tctcactccc actgtctcgt
2821 agaattacac tccttcctgg ggatccctct tcctgcagcc ttgtccttgg ggagtacagg
2881 gaagtacctg cagtgaccct gcccccatga ccttggccag gcaggatgat tccagagccc
2941 gtactgtggg gatcctcact gaccagccca gccccatccg caagccaggc tgggcctggg
3001 cataacttcg ctgggctctc ccaagaccat cagcagtgca tccagccccc tggggcctgg
3061 gctgctgctg gttcttcatc agtcccttgg tctctagcct cggccagggc tgctctgctc
3121 tccgccctcc tttgtgtatc aagtgtcgct cacagcccca ttcactgggg agcctttcgg
3181 atctatttgg tctttctcat gtcccccact ggtctgtacc ccagggagcg ggtgcttgta
3241 ctgtgtgaat ccagtgttca cattcacact taatgacttc cttggcacca atcatgtatt
3301 tcaccgtttg cactttttgt atttcaataa aaatgttgat gcaaaaaaaa aaaaaaaaaa
3361 aaaaaaaaaa aa
//