LOCUS BC017839 1306 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens caspase 4, apoptosis-related cysteine peptidase, mRNA
(cDNA clone MGC:22515 IMAGE:4699374), complete cds.
ACCESSION BC017839
VERSION BC017839.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1306)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1306)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 36 Row: p Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 15451908.
FEATURES Location/Qualifiers
source 1..1306
/db_xref="H-InvDB:HIT000038160"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22515 IMAGE:4699374"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_61"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1306
/gene="CASP4"
/gene_synonym="ICE(rel)II"
/gene_synonym="ICEREL-II"
/gene_synonym="ICH-2"
/gene_synonym="Mih1/TX"
/gene_synonym="TX"
/db_xref="GeneID:837"
/db_xref="HGNC:HGNC:1505"
/db_xref="MIM:602664"
CDS 40..1173
/gene="CASP4"
/gene_synonym="ICE(rel)II"
/gene_synonym="ICEREL-II"
/gene_synonym="ICH-2"
/gene_synonym="Mih1/TX"
/gene_synonym="TX"
/codon_start=1
/product="caspase 4, apoptosis-related cysteine peptidase"
/protein_id="AAH17839.1"
/db_xref="GeneID:837"
/db_xref="HGNC:HGNC:1505"
/db_xref="MIM:602664"
/translation="MAEGNHRKKPLKVLESLGKDFLTGVLDNLVEQNVLNWKEEEKKK
YYDAKTEDKVRVMADSMQEKQRMAGQMLLQTFFNIDQISPNKKAHPNMEAGPPESGES
TDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFDHLPPRNGADFDIT
GMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICG
TVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLE
VASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQKYS
WCCHLEEVFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPGN"
BASE COUNT 430 a 295 c 288 g 293 t
ORIGIN
1 cttttccaac gctgtaaaaa aggacagagg ctgttcccta tggcagaagg caaccacaga
61 aaaaagccac ttaaggtgtt ggaatccctg ggcaaagatt tcctcactgg tgttttggat
121 aacttggtgg aacaaaatgt actgaactgg aaggaagagg aaaaaaagaa atattacgat
181 gctaaaactg aagacaaagt tcgggtcatg gcagactcta tgcaagagaa gcaacgtatg
241 gcaggacaaa tgcttcttca aacctttttt aacatagacc aaatatcccc caataaaaaa
301 gctcatccga atatggaggc tggaccacct gagtcaggag aatctacaga tgccctcaag
361 ctttgtcctc atgaagaatt cctgagacta tgtaaagaaa gagctgaaga gatctatcca
421 ataaaggaga gaaacaaccg cacacgcctg gctctcatca tatgcaatac agagtttgac
481 catctgcctc cgaggaatgg agctgacttt gacatcacag ggatgaagga gctacttgag
541 ggtctggact atagtgtaga tgtagaagag aatctgacag ccagggatat ggagtcagcg
601 ctgagggcat ttgctaccag accagagcac aagtcctctg acagcacatt cttggtactc
661 atgtctcatg gcatcctgga gggaatctgc ggaactgtgc atgatgagaa aaaaccagat
721 gtgctgcttt atgacaccat cttccagata ttcaacaacc gcaactgcct cagtctgaag
781 gacaaaccca aggtcatcat tgtccaggcc tgcagaggtg caaaccgtgg ggaactgtgg
841 gtcagagact ctccagcatc cttggaagtg gcctcttcac agtcatctga gaacctggag
901 gaagatgctg tttacaagac ccacgtggag aaggacttca ttgctttctg ctcttcaacg
961 ccacacaacg tgtcctggag agacagcaca atgggctcta tcttcatcac acaactcatc
1021 acatgcttcc agaaatattc ttggtgctgc cacctagagg aagtatttcg gaaggtacag
1081 caatcatttg aaactccaag ggccaaagct caaatgccca ccatagaacg actgtccatg
1141 acaagatatt tctacctctt tcctggcaat tgaaaatgga agccacaagc agcccagccc
1201 tccttaatca acttcaagga gcaccttcat tagtacagct tgcatattta acattttgta
1261 tttcaataaa agtgaggaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//