LOCUS BC017717 2098 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens deiodinase, iodothyronine, type III, mRNA (cDNA clone
MGC:21279 IMAGE:4395664), complete cds.
ACCESSION BC017717
VERSION BC017717.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2098)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2098)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 27 Row: c Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 55750010.
FEATURES Location/Qualifiers
source 1..2098
/db_xref="H-InvDB:HIT000038101"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:21279 IMAGE:4395664"
/tissue_type="Duodenum, adenocarcinoma"
/clone_lib="NIH_MGC_88"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2098
/gene="DIO3"
/gene_synonym="5DIII"
/gene_synonym="D3"
/gene_synonym="DIOIII"
/db_xref="GeneID:1735"
/db_xref="HGNC:HGNC:2885"
/db_xref="MIM:601038"
CDS 73..909
/gene="DIO3"
/gene_synonym="5DIII"
/gene_synonym="D3"
/gene_synonym="DIOIII"
/codon_start=1
/transl_except=(pos:502..504,aa:Sec)
/product="deiodinase, iodothyronine, type III"
/protein_id="AAH17717.2"
/db_xref="GeneID:1735"
/db_xref="HGNC:HGNC:2885"
/db_xref="MIM:601038"
/translation="MLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLWLLDFLCIRKH
FLGRRRRGQPEPEVELNSEGEEVPPDDPPICVSDDNRLCTLASLKAVWHGQKLDFFKQ
AHEGGPAPNSEVVLPDGFQSQHILDYAQGNRPLVLNFGSCTUPPFMARMSAFQRLVTK
YQRDVDFLIIYIEEAHPSDGWVTTDSPYIIPQHRSLEDRVSAARVLQQGAPGCALVLD
TMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDGYQVSELRTWLERYDEQLHGARPR
RV"
BASE COUNT 501 a 590 c 594 g 413 t
ORIGIN
1 cgccaggcca cgtcgcggtt ggtggtcgga gagggcgagg ggtcccaggg ggcttcgggg
61 cctgcagcca ccatgctccg ctccctgctg cttcactcct tgaggctctg cgcccagacc
121 gcctcgtgcc tcgtgctctt cccgcgcttc ctcggcacgg ccttcatgct ctggcttctc
181 gatttcttgt gtatccgcaa gcatttcctg ggccgccgcc gccgggggca gcccgagccc
241 gaagtggagc tcaacagtga aggcgaggag gtgcctcccg atgacccgcc catctgcgtg
301 tccgacgaca accgcctgtg caccctggcg tcgctcaagg cggtgtggca tggccagaag
361 ttggatttct tcaagcaggc gcacgagggc ggtccggcgc ccaactccga ggtggttctg
421 cccgacggct tccagagcca gcacatcctc gactacgcgc aagggaaccg cccgctggtt
481 ctcaatttcg gcagctgcac ctgaccaccg ttcatggcgc gcatgagcgc cttccagcgc
541 ctggtcacta agtaccagcg cgacgtcgac ttcctcatca tctacatcga ggaagcgcac
601 ccctccgacg gctgggtcac cacggactct ccctacatca tcccacagca ccggagcctg
661 gaggaccggg tcagcgcagc gagggtactg cagcaaggtg cacccggctg cgctctggtc
721 ctcgacacca tggccaactc cagcagctcg gcctatggcg cctacttcga gcgtctctat
781 gtcatccaga gtggcactat tatgtaccag ggcggccgtg gccccgacgg ctaccaggtc
841 tctgagctgc gcacttggtt ggaacgctat gatgagcaac tgcacggcgc tcggccccgg
901 agggtgtaaa catccaacgg acaattgact gaacttggtg ggctgggcct tcgagccttc
961 gaagcccacg tgcaagcgcc tcaaaccaag tcacgcttgg cgaggcccca gtgacactga
1021 tgtgctgagc caccatttca gactgagtct gcaccctcag ccacatgaac aatctcccct
1081 acctccctgg gactctgctt ctgtaactgt ctcattcaca cctgcctggc tcactggaaa
1141 tcctcttttg agcgcgggat atggcttgcc cttgtccgtg tgcccccagg actttgcctc
1201 tacagcattt tcttacaccc cctccccagc gtgccctcag ccaagtgctt tggcccggtg
1261 cttcccgcag ctgcacagag accttggcca cgcccgcgcg ccctgagcgc agctgggttc
1321 caggagactc tcagctcagc tgagctagtt gcctggcacc cacctgtcgc gcgcggagag
1381 ggggttccct gttgcttttg tgtctgtttc ctgtccctgg taggggaagt gatgtcgtgg
1441 atggggaggg gtgggcaggg tagtttcccc cgcttgtttt gggtgcacag gagccccact
1501 gctgatgacg aactatctct aactggtctt gaccacgagc tagttctgaa ttgcaggggc
1561 ctcaaagcag cacctaaacc ttgaggggga gggtgctctg ggtttccgtg aggtaaccac
1621 cttaaatggg agggaagttg gggtgtctgc tttgggacca gaggaagata gcttgagagg
1681 cattggcgag gttcgcagcg ccccagggag agagaaaaag ctgagactcc tggggaatga
1741 cgttggggtg atggagtccg gggaaagaga ggtgggggga gagcctgagg tccccaagtg
1801 aggggagtcc taggcagagc tgctgattgt ggggctggga ggtggagggc ccctgattcg
1861 aaggccattt ggtgagtgtt ttgctggaaa tatttcctgt atataaactt ctttcaatct
1921 acaataataa aggcttgagg taaactgctt aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1981 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2041 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//