LOCUS BC017444 1641 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens fumarate hydratase, mRNA (cDNA clone MGC:15363
IMAGE:3606118), complete cds.
ACCESSION BC017444
VERSION BC017444.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1641)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1641)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 23 Row: n Column: 7.
FEATURES Location/Qualifiers
source 1..1641
/db_xref="H-InvDB:HIT000038011"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:15363 IMAGE:3606118"
/tissue_type="Uterus, endometrium adenocarcinoma"
/clone_lib="NIH_MGC_44"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1641
/gene="FH"
/gene_synonym="HLRCC"
/gene_synonym="LRCC"
/gene_synonym="MCL"
/gene_synonym="MCUL1"
/db_xref="GeneID:2271"
/db_xref="HGNC:HGNC:3700"
/db_xref="MIM:136850"
CDS 16..1548
/gene="FH"
/gene_synonym="HLRCC"
/gene_synonym="LRCC"
/gene_synonym="MCL"
/gene_synonym="MCUL1"
/codon_start=1
/product="fumarate hydratase"
/protein_id="AAH17444.1"
/db_xref="GeneID:2271"
/db_xref="HGNC:HGNC:3700"
/db_xref="MIM:136850"
/translation="MYRALRLLARSRPLVRAPAAALASAPGLGGAAVPSFWPPNAARM
ASQNSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRA
AAEVNQDYGLDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNR
AIEMLGGELGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDAL
DAKSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGG
TAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACS
LMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHV
AVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMN
ESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLG
PK"
BASE COUNT 521 a 333 c 386 g 401 t
ORIGIN
1 agctccctca gcaccatgta ccgagcactt cggctcctcg cgcgctcgcg tcccctcgtg
61 cgggctccag ccgcagcctt agcttcggct cccggcttgg gtggcgcggc cgtgccctcg
121 ttttggcctc cgaacgcggc tcgaatggca agccaaaatt ccttccggat agaatatgat
181 acctttggtg aactaaaggt gccaaatgat aagtattatg gcgcccagac cgtgagatct
241 acgatgaact ttaagattgg aggtgtgaca gaacgcatgc caaccccagt tattaaagct
301 tttggcatct tgaagcgagc ggccgctgaa gtaaaccagg attatggtct tgatccaaag
361 attgctaatg caataatgaa ggcagcagat gaggtagctg aaggtaaatt aaatgatcat
421 tttcctctcg tggtatggca gactggatca ggaactcaga caaatatgaa tgtaaatgaa
481 gtcattagca atagagcaat tgaaatgtta ggaggtgaac ttggcagcaa gatacctgtg
541 catcccaacg atcatgttaa taaaagccag agctcaaatg atacttttcc cacagcaatg
601 cacattgctg ctgcaataga agttcatgaa gtactgttac caggactaca gaagttacat
661 gatgctcttg atgcaaaatc caaagagttt gcacagatca tcaagattgg acgtactcat
721 actcaggatg ctgttccact tactcttggg caggaattta gtggttatgt tcaacaagta
781 aaatatgcaa tgacaagaat aaaagctgcc atgccaagaa tctatgagct cgcagctgga
841 ggcactgctg ttggtacagg tttaaatact agaattggct ttgcagaaaa ggttgctgca
901 aaagtggctg cacttacagg cttgcctttt gtcactgctc cgaataaatt tgaagctctg
961 gctgctcatg acgctctggt tgagctcagt ggagccatga acactactgc ctgcagtctg
1021 atgaagatag caaatgatat tcgatttttg ggttctggtc ctcggtcagg tctgggagaa
1081 ttgatcttgc ctgaaaatga accaggaagc agtatcatgc caggcaaggt gaaccctact
1141 cagtgtgaag caatgaccat ggttgcagcc caagtcatgg ggaaccatgt tgctgtcact
1201 gtcggaggca gcaatggaca ttttgagttg aatgttttca agccaatgat gattaaaaat
1261 gtgttacact cagccaggct gctgggggat gcttcagttt cctttacaga aaactgcgtg
1321 gtgggaatcc aggccaatac agaaaggatc aacaagctga tgaatgagtc tctaatgttg
1381 gtgacagctc tcaatcctca tatagggtat gacaaggcag caaagattgc taagacagca
1441 cacaaaaatg gatcaacctt aaaggaaact gctatcgaac ttggctatct cacagcagag
1501 cagtttgacg aatgggtaaa acctaaggac atgctgggtc caaagtgatt tacataaatt
1561 tataatgaaa ataaacatgt ataaaattta aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1621 aaaaaaaaaa aaaaaaaaaa a
//