LOCUS BC017419 1713 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cereblon, mRNA (cDNA clone MGC:27358 IMAGE:4672890),
complete cds.
ACCESSION BC017419
VERSION BC017419.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1713)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1713)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 38 Row: i Column: 16.
FEATURES Location/Qualifiers
source 1..1713
/db_xref="H-InvDB:HIT000037998"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:27358 IMAGE:4672890"
/tissue_type="Lung, mucoepidermoid carcinoma"
/clone_lib="NIH_MGC_59"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1713
/gene="CRBN"
/gene_synonym="MGC27358"
/db_xref="GeneID:51185"
/db_xref="HGNC:HGNC:30185"
/db_xref="MIM:609262"
CDS 19..1347
/gene="CRBN"
/gene_synonym="MGC27358"
/codon_start=1
/product="cereblon"
/protein_id="AAH17419.1"
/db_xref="GeneID:51185"
/db_xref="HGNC:HGNC:30185"
/db_xref="MIM:609262"
/translation="MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKP
NIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLF
HPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAI
GRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQ
CSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSN
PIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTK
NEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCK
ICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL"
BASE COUNT 572 a 321 c 365 g 455 t
ORIGIN
1 gggggcgggt aaacagacat ggccggcgaa ggagatcagc aggacgctgc gcacaacatg
61 ggcaaccacc tgccgctcct gcctgcagag agtgaggaag aagatgaaat ggaagttgaa
121 gaccaggata gtaaagaagc caaaaaacca aacatcataa attttgacac cagtctgccg
181 acatcacata catacctagg tgctgatatg gaagaatttc atggcaggac tttgcacgat
241 gacgacagct gtcaggtgat tccagttctt ccacaagtga tgatgatcct gattcccgga
301 cagacattac ctcttcagct ttttcaccct caagaagtca gtatggtgcg gaatttaatt
361 cagaaagata gaacctttgc tgttcttgca tacagcaatg tacaggaaag ggaagcacag
421 tttggaacaa cagcagagat atatgcctat cgagaagaac aggattttgg aattgagata
481 gtgaaagtga aagcaattgg aagacaaagg ttcaaagtcc ttgagctaag aacacagtca
541 gatggaatcc agcaagctaa agtgcaaatt cttcccgaat gtgtgttgcc ttcaaccatg
601 tctgcagttc aattagaatc cctcaataag tgccagatat ttccttcaaa acctgtctca
661 agagaagacc aatgttcata taaatggtgg cagaaatacc agaagagaaa gtttcattgt
721 gcaaatctaa cttcatggcc tcgctggctg tattccttat atgatgctga gaccttaatg
781 gacagaatca agaaacagct acgtgaatgg gatgaaaatc taaaagatga ttctcttcct
841 tcaaatccaa tagatttttc ttacagagta gctgcttgtc ttcctattga tgatgtattg
901 agaattcagc tccttaaaat tggcagtgct atccagcgac ttcgctgtga attagacatt
961 atgaataaat gtacttccct ttgctgtaaa caatgtcaag aaacagaaat aacaaccaaa
1021 aatgaaatat tcagtttatc cttatgtggg ccgatggcag cttatgtgaa tcctcatgga
1081 tatgtgcatg agacacttac tgtgtataag gcttgcaact tgaatctgat aggccggcct
1141 tctacagaac acagctggtt tcctgggtat gcctggactg ttgcccagtg taagatctgt
1201 gcaagccata ttggatggaa gtttacggcc accaaaaaag acatgtcacc tcaaaaattt
1261 tggggcttaa cgcgatctgc tctgttgccc acgatcccag acactgaaga tgaaataagt
1321 ccagacaaag taatactttg cttgtaaaca gatgtgatag agataaagtt agttatctaa
1381 caaattggtt atattctaag atctgctttg gaaattattg cctctgatac atacctaagt
1441 aaacataaca ttaataccta agtaaacata acattacttg gagggttgca gtttctaagt
1501 gaaactgtat ttgaaacttt taagtatact ttaggaaaca agcatgaacg gcagtctaga
1561 ataccagaaa catctacttg ggtagcttgg tgccattatc ctgtggaatc tgatatgtct
1621 ggtagcatgt cattgatggg acatgaagac atctttggaa atgatgagat tatttcctgt
1681 gttaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
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