LOCUS BC017366 2454 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens CCR4-NOT transcription complex, subunit 8, mRNA (cDNA
clone MGC:1191 IMAGE:3506054), complete cds.
ACCESSION BC017366
VERSION BC017366.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2454)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2454)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (13-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC017366.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 7 Row: f Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24496777.
FEATURES Location/Qualifiers
source 1..2454
/db_xref="H-InvDB:HIT000037972"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1191 IMAGE:3506054"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2454
/gene="CNOT8"
/gene_synonym="CAF1"
/gene_synonym="CALIF"
/gene_synonym="hCAF1"
/gene_synonym="POP2"
/db_xref="GeneID:9337"
/db_xref="MIM:603731"
CDS 182..1060
/gene="CNOT8"
/gene_synonym="CAF1"
/gene_synonym="CALIF"
/gene_synonym="hCAF1"
/gene_synonym="POP2"
/codon_start=1
/product="CNOT8 protein"
/protein_id="AAH17366.1"
/db_xref="GeneID:9337"
/db_xref="MIM:603731"
/translation="MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFP
GVVVRPIGEFRSSIDYQYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFN
LTEDMYSQDSIDLLANSGLQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGY
DFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDL
QRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDS
AQEKMSILAIINNMQQ"
misc_feature 182..970
/gene="CNOT8"
/gene_synonym="CAF1"
/gene_synonym="CALIF"
/gene_synonym="hCAF1"
/gene_synonym="POP2"
/note="Region: COG5228, POP2, mRNA deadenylase subunit
[RNA processing and modification]"
/db_xref="CDD:COG5228"
BASE COUNT 705 a 471 c 529 g 749 t
ORIGIN
1 aaaagagctc cgggccaggg gctgccgtcg ccgccgtcgg ggagtcagcc cgccagcccg
61 ccagctcgtc agcccgccag ccagcgcttc gcgggccctg tcggtcccga tcagaccaaa
121 cattgtctgg cttgcactgt aaaactagtt agctgaagac gacttctcag gtttcttcag
181 gatgcctgca gcacttgtgg agaatagcca ggttatctgt gaagtgtggg ccagtaatct
241 agaagaagag atgaggaaga tccgagaaat cgtgctcagt tacagttata ttgccatgga
301 cacagaattt ccaggtgttg tggtgcgacc aattggtgaa tttcgtagtt ccatagatta
361 ccaatatcag cttctgcggt gcaatgttga ccttttaaaa attatccagc tgggccttac
421 attcacaaat gagaagggag agtatccttc tggaatcaat acttggcagt tcaatttcaa
481 atttaacctt acagaggaca tgtactccca ggattccata gatctccttg ctaactcagg
541 actacagttt cagaagcatg aagaggaagg gattgacaca ctgcactttg cagagctgct
601 tatgacatca ggagtggttc tctgtgacaa tgtcaaatgg ctttcatttc atagtggcta
661 tgattttggc tatatggtaa agttgcttac agattctcgt ttgccagaag aggaacatga
721 attctttcat attctgaacc ttttcttccc atccatttat gatgtgaaat acctgatgaa
781 gagctgcaaa aatcttaagg gaggtcttca ggaagttgct gatcagttgg atttgcagag
841 gattggaagg cagcaccagg caggctcaga ctcactgctg acaggaatgg ctttctttag
901 gatgaaagag ttgttttttg aggacagcat tgatgatgcc aagtactgtg ggcggctcta
961 tggcttaggc acaggagtgg cccagaagca gaatgaggat gtggactctg cccaggagaa
1021 gatgagcatc ctggcgatta tcaacaacat gcagcagtga tggcgccagg ctctgcaggg
1081 tgggcctgat cccagagtgg tgcttactgt gctgactgtg tacttatctt ccccaagaga
1141 aaatgcttct tttgaccaca ctgtacctac catctgcatt gagcagaaag acttttgttt
1201 tactgaagac aaaagatgtt tttattttag acccagaaga gaggagtttg ctctgaattt
1261 gtaaataagt cttccccatt cctcatactc gagcctctcc tctctggttg cctcctgcca
1321 ccagcatcca tggctcattt gacacctttt taaatatcag gacaagtctg aaacaaagta
1381 gtaaaatgta tataactctt acctgttgtc attctttttc ttttaaattt gttgctaatc
1441 tctgataatg aagattctta ctctgattct cagctgagct gtgagggctt ccagggaaaa
1501 tggaacaaaa tggtgttctt aggtaatggg ttgtagatac tgagtcttcc tttccttttc
1561 tgacccttct cgaggacatt tgctttcctc acacttttgt agtctctctt tacatattac
1621 tatatggaaa tgaattgctc tgtgctgaaa tttgaagacc agataatgaa actgaaaagc
1681 aaacaatttt actgaatctg tctacccttc attcatgaga actccagaat gagtgttgac
1741 cactgaagca tcttttaagt ctgtgttcca ttgtgccatt caggtttgct gtcacatatg
1801 catcatctga aatcatttga aatttttgta caataaaata tcctggattt gatcctgaag
1861 gaaactagta agatcagatt tttgggtcat gtctgttgta ttttcagtaa tgtgatttca
1921 gatggtcatc tggattctcc cacttctcta ctccattatt tctctacttt tccttccagc
1981 aaacctgaaa cgtgagggag atggattaat gtgagtaaca ggaatgtgtc tttaaaaagc
2041 tagagtggtt acatttaatc aggcagtaag ataatttggg ttcttgagtt gttttggagt
2101 aatatcccac aactggggta ggaagctcag gacttttttc tttaaagcta gtcatttcaa
2161 aagcatattg tatttttttg aatgactaca gtatggacaa tttcaaaaac caaaacccac
2221 tttggattgg tggaagtaaa aactggtaac tcactcaagt gaatgaatgg tcttgcattt
2281 taaaagctta tgggaaactc aatttgaaat gattagaaaa tgtcaagtat tataagctgg
2341 tatttaagat gcttgtaaat actatttatg tttttaattt tgtaaaataa agatttcttt
2401 ttaaccactg gcaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//