LOCUS BC017355 2191 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens karyopherin alpha 3 (importin alpha 4), mRNA (cDNA
clone MGC:29709 IMAGE:5020312), complete cds.
ACCESSION BC017355
VERSION BC017355.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2191)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2191)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC017355.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 39 Row: n Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein.
FEATURES Location/Qualifiers
source 1..2191
/db_xref="H-InvDB:HIT000037964"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:29709 IMAGE:5020312"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2191
/gene="KPNA3"
/gene_synonym="hSRP1"
/gene_synonym="IPOA4"
/gene_synonym="SRP1gamma"
/gene_synonym="SRP4"
/db_xref="GeneID:3839"
/db_xref="HGNC:HGNC:6396"
/db_xref="MIM:601892"
CDS 25..1590
/gene="KPNA3"
/gene_synonym="hSRP1"
/gene_synonym="IPOA4"
/gene_synonym="SRP1gamma"
/gene_synonym="SRP4"
/codon_start=1
/product="karyopherin alpha 3 (importin alpha 4)"
/protein_id="AAH17355.1"
/db_xref="GeneID:3839"
/db_xref="HGNC:HGNC:6396"
/db_xref="MIM:601892"
/translation="MAENPSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEH
LLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSD
RNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVP
LFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLR
NVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQ
IQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNL
LSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAI
SNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIA
EIIEECGGLEKIEVLQQHENEDIYKLAFEIIDQYFSGDDIDEDPCLIPEATQGGTYNF
DPTANLQTKEFNF"
BASE COUNT 715 a 454 c 444 g 578 t
ORIGIN
1 ccgccgccgg agccgcgcgc agccatggcc gagaacccca gcttggagaa ccaccgcatc
61 aagagcttca agaacaaggg ccgcgatgtg gaaacaatgc gaagacatag aaatgaagtg
121 acagtggaac tgcggaagaa caaaagagat gaacacttat tgaaaaagag aaatgttccc
181 caagaagaaa gtctagaaga ttcagatgtt gatgctgatt ttaaagcaca aaatgtaacc
241 ctagaagcta tattgcagaa tgccacaagt gataacccag tggtccaatt gagtgctgtc
301 caggcagcaa gaaaactgtt atccagtgac agaaatccac cgattgatga cttaataaaa
361 tctgggattt taccaattct agtcaaatgt ctagaaaggg atgataatcc ttcattacag
421 tttgaagctg cttgggcatt aactaacata gcatcaggaa cttctgcaca gactcaagct
481 gttgtgcagt ctaatgcagt acctcttttt ctgagacttc ttcgttcacc acatcagaat
541 gtttgtgaac aagcagtatg ggctttggga aacattatag gtgatggtcc tcaatgtaga
601 gattatgtca tatcactggg agttgtcaaa cctcttctgt ccttcatcag tccctccatc
661 cccatcacct tccttcggaa cgtcacatgg gtcattgtca atctctgcag gaataaggat
721 cccccaccgc ctatggagac agttcaggag attttgccag ctttatgtgt cctcatatac
781 catacagata taaacattct tgtagacact gtttgggctc tgtcatactt gacagatgga
841 ggtaatgaac agatacagat ggttattgat tcaggagttg tgccctttct tgtgcccctt
901 ctgagccatc aggaagtcaa agttcaaaca gcagccctca gagcagttgg caacatagtg
961 actggcaccg acgagcagac ccaggttgtt ctcaattgtg atgtcctgtc acacttccca
1021 aatctcttat cacacccaaa agagaagata aataaggaag cagtgtggtt cctttccaac
1081 ataacagcag gcaaccagca acaagttcaa gctgtaatag atgctggatt aattcctatg
1141 ataattcatc agcttgctaa gggggacttt ggaacacaaa aagaagctgc ttgggcaatc
1201 agcaacttaa caataagtgg cagaaaagat caggttgagt accttgtaca gcagaatgta
1261 ataccaccgt tctgtaattt actgtcagtg aaagattctc aagtggttca ggtggttcta
1321 gatggtctaa aaaacattct gataatggcc ggtgatgaag caagcacaat agctgaaata
1381 atagaggaat gtggaggttt ggagaaaatt gaagttttac agcaacatga aaatgaagac
1441 atatataaat tagcatttga aatcatagat cagtatttct ctggtgatga tattgatgaa
1501 gatccctgcc tcattcctga agcaacacaa ggaggtacct acaattttga tccaacagcc
1561 aaccttcaaa caaaagaatt taatttttaa attcagttga gtgcagcatc tttcccacat
1621 tcaatatgaa gcaccaccag atggctacca aatgataaga acaacagcaa caaaaggctc
1681 caaaacacac atgcctcttt gttttgatgc ttctaaagca agccatgtct cagtcacttt
1741 gcagttgcca aaagtcacta tcacatggac tgtaaatgca tatgcatgat ttcctaaact
1801 gttttagaac tctccttaac aatctcaact accctatttt tccctgttcc ctggtgccac
1861 aggctgacaa ctgcagtctc cagtttagaa taaatattcc atagtggtga catgtcagct
1921 gcccactgat actcctttgg aaaatggtgc gctgtggatc aagacacttt ggtatgatgc
1981 atatacaagt tggaagacta aagaggtgca gtgtgatctg agcctccatc attgtcctcc
2041 acaaacatat tttcatattc tttatgtgga agaatagatt ttaaagtaca agccaaatga
2101 ttttcattgg tggaactgac acaaaaaaag taacttaaaa acaagaaact tggttattga
2161 ataaacagat aagttttaaa aaaaaaaaaa a
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