LOCUS BC017296 1428 bp mRNA linear HUM 04-OCT-2003
DEFINITION Homo sapiens sestrin 3, mRNA (cDNA clone MGC:29667 IMAGE:5016567),
complete cds.
ACCESSION BC017296
VERSION BC017296.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1428)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1428)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC017296.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 39 Row: m Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis, Similarity but not identity to protein.
FEATURES Location/Qualifiers
source 1..1428
/db_xref="H-InvDB:HIT000037928"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:29667 IMAGE:5016567"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1428
/gene="SESN3"
/gene_synonym="MGC29667"
/gene_synonym="SEST3"
/db_xref="GeneID:143686"
/db_xref="MIM:607768"
CDS 187..1152
/gene="SESN3"
/gene_synonym="MGC29667"
/gene_synonym="SEST3"
/codon_start=1
/product="SESN3 protein"
/protein_id="AAH17296.1"
/db_xref="GeneID:143686"
/db_xref="MIM:607768"
/translation="MNRGGGSPSAAANYLLCTNCRKVLRKDKRIRVSQPLTRGPSAFI
PEKEVVQANTVDERTNFLVEEYSTSGRLDNITQVMSLHTQYLESFLRSQFYMLRMDGP
LPLPYRHYIAIMAAARHQCSYLINMHVDEFLKTGGIAEWLNGLEYVPQRLKNLNEINK
LLAHRPWLITKEHIQKLVKTGENNWSLPELVHAVVLLAHYHALASFVFGSGINPERDP
EISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEALMERMKRLQEER
EDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSGAFLHFFAF"
misc_feature 307..729
/gene="SESN3"
/gene_synonym="MGC29667"
/gene_synonym="SEST3"
/note="COG2128; Region: Uncharacterized conserved protein
[Function unknown]"
/db_xref="CDD:COG2128"
BASE COUNT 388 a 317 c 331 g 392 t
ORIGIN
1 cgcggtggtc gcctctggca gtgccgctag ctttcaggca gtcgcctctc ctcccgacat
61 cccgccttga ggaggctgag gcggaatcgc ggctggcggc ggggggacgg accggccctg
121 cagtggccgc agtgacagcc cggacccggc cctccgcccg ctctcgcctc ggcgcccgca
181 gccacgatga accggggcgg cggcagcccg tcggccgccg ccaactacct gctctgtacc
241 aactgccgga aagtgctgcg gaaggataaa agaatcagag tgtctcaacc cttgacaaga
301 ggaccaagtg cctttattcc agagaaggaa gttgtccaag caaacacagt ggatgaacgt
361 actaactttc ttgtggaaga atactctaca tccggtcgtc tggacaacat cacacaggtc
421 atgagtttac acactcagta cctggagtct ttcttgcgga gccagtttta catgttgcgc
481 atggatggtc cccttcctct accatacagg cactatattg caataatggc tgcagctaga
541 catcagtgtt cttacttaat aaacatgcat gtggatgaat ttttaaagac tggaggtatt
601 gctgagtggt tgaatggttt ggaatatgtg ccacaaagac tgaaaaatct taatgaaatt
661 aataagctgc tagcacatcg accttggctg atcacaaaag agcacattca gaaacttgtc
721 aaaactggag aaaataattg gtctctgcct gaactggtac atgctgtggt cctcctggca
781 cattatcatg ctttggcaag ctttgttttt ggtagtggta tcaatccaga gagagatcca
841 gaaatctcca atggattcag gctaatatca gtcaacaatt tctgcgtttg tgatcttgct
901 aatgacaaca acatagagaa tgcatctctt tcaggcagca actttgggat tgtggattct
961 ctaagtgagc tagaggcctt aatggaaagg atgaaaagac ttcaagaaga aagggaagat
1021 gaagaggcgt ctcaagaaga aatgagcact cgttttgaaa aggagaagaa agaaagtctt
1081 tttgtggtct ctggagatac ttttcattca tttcctcatt caggtgcttt tttgcacttt
1141 tttgcctttt agttgttctt agaaccctga cagggcaact tcagtgtttt ccatgtggat
1201 atgtaaaaat gattctgcta ccatctttct cttatttagt tctcctcttc tatcttaccc
1261 tcatgctatt gctttccctc aggctggttc atccttgaat gtatttcaga ttgagttgag
1321 agaaactttc agctttgtag ttcatactct atcctggata aaatgttatt taaagcagat
1381 cagttactta taaagttaga tagacataaa aaaaaaaaaa aaaaaaaa
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