LOCUS BC017200 2912 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens calpain 1, (mu/I) large subunit, mRNA (cDNA clone
MGC:3970 IMAGE:3629894), complete cds.
ACCESSION BC017200
VERSION BC017200.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2912)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2912)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 31, 2003 this sequence version replaced BC017200.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 12 Row: a Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 12408655.
FEATURES Location/Qualifiers
source 1..2912
/db_xref="H-InvDB:HIT000037870"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3970 IMAGE:3629894"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2912
/gene="CAPN1"
/gene_synonym="CANP"
/gene_synonym="CANPL1"
/gene_synonym="muCANP"
/gene_synonym="muCL"
/db_xref="GeneID:823"
/db_xref="HGNC:HGNC:1476"
/db_xref="MIM:114220"
CDS 20..2164
/gene="CAPN1"
/gene_synonym="CANP"
/gene_synonym="CANPL1"
/gene_synonym="muCANP"
/gene_synonym="muCL"
/codon_start=1
/product="calpain 1, (mu/I) large subunit"
/protein_id="AAH17200.1"
/db_xref="GeneID:823"
/db_xref="HGNC:HGNC:1476"
/db_xref="MIM:114220"
/translation="MSEEIITPVYCTGVSAQVQKQRARELGLGRHENAIKYLGQDYEQ
LRVRCLQSGTLFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGA
TRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWV
DVVVDDLLPIKDGKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFT
GGVTEWYELRKAPSDLYQIILKALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSV
TGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGEF
WMSFRDFMREFTRLEICNLTPDALKSRTIRKWNTTLYEGTWRRGSTAGGCRNYPATFW
VNPQFKIRLDETDDPDDYGDRESGCSFVLALMQKHRRRERRFGRDMETIGFAVYEVPP
ELVGQPAVHLKRDFFLANASRARSEQFINLREVSTRFRLPPGEYVVVPSTFEPNKEGD
FVLRFFSEKSAGTVELDDQIQANLPDEQVLSEEEIDENFKALFRQLAGEDMEISVKEL
RTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLSIF
RKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRYSEPDLAVDFDNFVCCLVRL
ETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA"
BASE COUNT 600 a 885 c 859 g 568 t
ORIGIN
1 caaacacccc tcccccagga tgtcggagga gatcatcacg ccggtgtact gcactggggt
61 gtcagcccaa gtgcagaagc agcgggccag ggagctgggc ctgggccgcc atgagaatgc
121 catcaagtac ctgggccagg attatgagca gctgcgggtg cgatgcctgc agagtgggac
181 cctcttccgt gatgaggcct tccccccggt accccagagc ctgggttaca aggacctggg
241 tcccaattcc tccaagacct atggcatcaa gtggaagcgt cccacggaac tgctgtcaaa
301 cccccagttc attgtggatg gagctacccg cacagacatc tgccagggag cactggggga
361 ctgctggctc ttggcggcca tcgcctccct cactctcaac gacaccctcc tgcaccgagt
421 ggttccgcac ggccagagct tccagaatgg ctatgccggc atcttccatt tccagctgtg
481 gcaatttggg gagtgggtgg acgtggtcgt ggatgacctg ctgcccatca aggacgggaa
541 gctagtgttc gtgcactctg ccgaaggcaa cgagttctgg agcgccctgc ttgagaaggc
601 ctatgccaag gtaaatggca gctacgaggc cctgtcaggg ggcagcacct cagagggctt
661 tgaggacttc acaggcgggg ttaccgagtg gtacgagttg cgcaaggctc ccagtgacct
721 ctaccagatc atcctcaagg cgctggagcg gggctccctg ctgggctgct ccatagacat
781 ctccagcgtt ctagacatgg aggccatcac tttcaagaag ttggtgaagg gccatgccta
841 ctctgtgacc ggggccaagc aggtgaacta ccgaggccag gtggtgagcc tgatccggat
901 gcggaacccc tggggcgagg tggagtggac gggagcctgg agcgacagct cctcagagtg
961 gaacaacgtg gacccatatg aacgggacca gctccgggtc aagatggagg acggggagtt
1021 ctggatgtca ttccgagact tcatgcggga gttcacccgc ctggagatct gcaacctcac
1081 acccgacgcc ctcaagagcc ggaccatccg caaatggaac accacactct acgaaggcac
1141 ctggcggcgg gggagcaccg cggggggctg ccgaaactac ccagccacct tctgggtgaa
1201 ccctcagttc aagatccggc tggatgagac ggatgacccg gacgactacg gggaccgcga
1261 gtcaggctgc agcttcgtgc tcgcccttat gcagaagcac cgtcgccgcg agcgccgctt
1321 cggccgcgac atggagacta ttggcttcgc ggtctacgag gtccctccgg agctggtggg
1381 ccagccggcc gtacacttga agcgtgactt cttcctggcc aatgcgtctc gggcgcgctc
1441 agagcagttc atcaacctgc gagaggtcag cacccgcttc cgcctgccac ccggggagta
1501 tgtggtggtg ccctccacct tcgagcccaa caaggagggc gacttcgtgc tgcgcttctt
1561 ctcagagaag agtgctggga ctgtggagct ggatgaccag atccaggcca atctccccga
1621 tgagcaagtg ctctcagaag aggagattga cgagaacttc aaggccctct tcaggcagct
1681 ggcaggggag gacatggaga tcagcgtgaa ggagttgcgg acaatcctca ataggatcat
1741 cagcaaacac aaagacctgc ggaccaaggg cttcagccta gagtcgtgcc gcagcatggt
1801 gaacctcatg gatcgtgatg gcaatgggaa gctgggcctg gtggagttca acatcctgtg
1861 gaaccgcatc cggaattacc tgtccatctt ccggaagttt gacctggaca agtcgggcag
1921 catgagtgcc tacgagatgc ggatggccat tgagtcggca ggcttcaagc tcaacaagaa
1981 gctgtacgag ctcatcatca cccgctactc ggagcccgac ctggcggtcg actttgacaa
2041 tttcgtttgc tgcctggtgc ggctagagac catgttccga tttttcaaaa ctctggacac
2101 agatctggat ggagttgtga cctttgactt gtttaagtgg ttgcagctga ccatgtttgc
2161 atgaggcagg gactcggtcc cccttgccgt gctcccctcc ctcctcgtct gccaagcctc
2221 gcctcctacc acaccacacc aggccacccc agctgcaagt gccttccttg gagcagagag
2281 gcagcctcgt cctcctgtcc cctctcctcc cagccaccat cgttcatctg ctccgggcag
2341 aactgtgtgg cccctgcctg tgccagccat gggctcggga tggactccct gggccccacc
2401 cattgccaag ccaggaaggc agctttcgct tgttcctgcc tcgggacagc cccgggtttc
2461 cccagcatcc tgatgtgtcc cctctcccca cttcagaggc cacccactca gcaccaccgg
2521 cctggccttg cctgcagact ataaactata accactagct cgacacagtc tgcagtccag
2581 gcgtgtggag ccgcctcccg gctcggggag gccccggggc tgggaacgcc tgtgccttcc
2641 tgcgccgaag ccaacgcccc ctctgtcctt ccctggccct gctgccgacc aggagctgcc
2701 cagcctgtgg gcggtcggcc ttccctcctt cgctcctttt ttatattagt gattttaaag
2761 gggactcttc agggacttgt gtactggtta tgggggtgcc agaggcacta ggcttggggt
2821 ggggaggtcc cgtgttccat atagaggaac cccaaataat aaaaggcccc acatctgtct
2881 gtgaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//