LOCUS BC017174 2798 bp mRNA linear HUM 27-OCT-2006
DEFINITION Homo sapiens dopamine beta-hydroxylase (dopamine
beta-monooxygenase), mRNA (cDNA clone MGC:2350 IMAGE:3163986),
complete cds.
ACCESSION BC017174
VERSION BC017174.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2798)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2798)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 8, 2003 this sequence version replaced BC017174.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: g Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 18426905.
FEATURES Location/Qualifiers
source 1..2798
/db_xref="H-InvDB:HIT000037853"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2350 IMAGE:3163986"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2798
/gene="DBH"
/gene_synonym="DBM"
/db_xref="GeneID:1621"
/db_xref="HGNC:HGNC:2689"
/db_xref="MIM:609312"
CDS 38..1849
/gene="DBH"
/gene_synonym="DBM"
/codon_start=1
/product="DBH protein"
/protein_id="AAH17174.1"
/db_xref="GeneID:1621"
/db_xref="HGNC:HGNC:2689"
/db_xref="MIM:609312"
/translation="MREAAFMYSTAVAIFLVILVAALQGSAPRESPLPYHIPLDPEGS
LELSWNVSYTQEAIHFQLLVRRLKAGVLFGMSDRGELENADLVVLWTDGDTAYFADAW
SDQKGQIHLDPQQDYQLLQVQRTPEGLTLLFKRPFGTCDPKDYLIEDGTVHLVYGILE
EPFRSLEAINGSGLQMGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQETTYWC
YIKELPKGFSRHHIIKYEPIVTKGNEALVHHMEVFQCAPEMDSVPHFSGPCDSKMKPD
RLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSG
IRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGIHI
FASQLHTHLTGRKVVTVLVRDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLIT
SCTYNTEDRELATVGGFGILEEMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRF
NNEDVCTCPQASVSQQFTSVPWNSFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQ
PLPKVISTLEEPTPQCPTSQGRSPAGPTVVSIGGGKG"
BASE COUNT 587 a 907 c 783 g 521 t
ORIGIN
1 cgccctcagt cgctgggcca gcctgcccgg ccccagcatg cgggaggcag ccttcatgta
61 cagcacagca gtggccatct tcctggtcat cctggtggcc gcactgcagg gctcggctcc
121 ccgtgagagc cccctcccct atcacatccc cctggacccg gaggggtccc tggagctctc
181 atggaatgtc agctacaccc aggaggccat ccatttccag ctcctggtgc ggaggctcaa
241 ggctggcgtc ctgtttggga tgtccgaccg tggcgagctt gagaacgcag atctcgtggt
301 gctctggacc gatggggaca ctgcctattt tgcggacgcc tggagtgacc agaaggggca
361 gatccacctg gatccccagc aggactacca gctgctgcag gtgcagagga ccccagaagg
421 cctgaccctg cttttcaaga ggccctttgg cacctgcgac cccaaggatt acctcattga
481 ggacggcact gtccacttgg tctacgggat cctggaggag ccgttccggt cactggaggc
541 catcaacggc tcgggcctgc agatggggct gcagagggtg cagctcctga agcccaatat
601 ccccgaaccg gagttgccct cagacgcgtg caccatggag gtccaagctc ccaatatcca
661 gatccccagc caggagacca cgtactggtg ctacattaag gagcttccaa agggcttctc
721 tcggcaccac attatcaagt acgagcccat cgtcaccaag ggcaatgagg cccttgtcca
781 ccacatggaa gtcttccagt gcgcccccga gatggacagc gtcccccact tcagcgggcc
841 ctgcgactcc aagatgaaac ccgaccgcct caactactgc cgccacgtgc tggccgcctg
901 ggccctgggt gccaaggcat tttactaccc agaggaagcc ggccttgcct tcgggggtcc
961 agggtcctcc agatatctcc gcctggaagt tcactaccac aacccactgg tgatagaagg
1021 acgaaacgac tcctcaggca tccgcttgta ctacacagcc aagctgcggc gcttcaacgc
1081 ggggatcatg gagctgggac tggtgtacac gccagtgatg gccattccac cacgggagac
1141 cgccttcatc ctcactggct actgcacgga caagtgcacc cagctggcac tgcctccctc
1201 cgggatccac atcttcgcct ctcagctcca cacacacctg actgggagaa aggtggtcac
1261 agtgctggtc cgggacggcc gggagtggga gatcgtgaac caggacaatc actacagccc
1321 tcacttccag gagatccgca tgttgaagaa ggtcgtgtcg gtccatccgg gagatgtgct
1381 catcacctcc tgcacgtaca acacggaaga ccgggagctg gccacagtgg ggggcttcgg
1441 gatcctggag gagatgtgtg tcaactacgt gcactactac ccccagacgc agctggagct
1501 ctgcaagagc gctgtggacg ccggcttcct gcagaagtac ttccacctca tcaacaggtt
1561 caacaacgag gatgtctgca cctgccctca ggcgtccgtg tctcagcagt tcacctctgt
1621 tccctggaac tccttcaacc gcgacgtact gaaggccctg tacagcttcg cgcccatctc
1681 catgcactgc aacaagtcct cagccgtccg cttccagggt gaatggaacc tgcagcccct
1741 gcccaaggtc atctccacac tggaagagcc caccccacag tgccccacca gccagggccg
1801 aagccctgct ggccccaccg ttgtcagcat tggtgggggc aaaggctgag gggggaccta
1861 ctcctccccc tcctccatgc tgtccctgtg ggctcacacc ggcactgtgc actctactct
1921 gcgacgatcc ccatggaaca gccctgcatg cccaggatga aggggccaga ccacgcccct
1981 gcctgagacc acggtccaat ccagccttct tcccccaggg tcccctgcat ggctgagagg
2041 gtgtgggtgc cctgttgacc taccctggac cgagtggacc acgacctcgt ccatttaaac
2101 ccggctgact cagtgcaggg acagcctgca cagtggtcca gggtccagcc ctccgccagc
2161 cctgttccgc ctcactgggt gtggcctggc ttctgggaca ggcaccatgc tgggccgggg
2221 tgtggaatca ccgggaacgc ccccgccccc gccccgctgc tcccggtgtg cagcgggtgc
2281 gggtgccgct taaacatttc cctgctgagt ggctcgtgtt tcacagtggg cggcttccct
2341 gcgacggagg caggaccagg catttagcta gttagagact cgcctgggaa attgctccat
2401 tcctgagtaa acagatattt tcgcccacct aaagggaagc cctgacaaca actatcacca
2461 aaagacgagg cggcaaagat ccagcggggc ttctgggcgc cggttccacg tggggtggaa
2521 ttattagcac cagcttgctt ctctgccggt ggggccagcg ctgaacagac cggggtggag
2581 tcagggctgt gctttccgcg tggttctgcc acttagggag tgtgccttgg gcgggccatt
2641 tcacattcct gaccctcact tttctcatct gtaaaaccag gctgatgccg tgcgggctaa
2701 tgagccaata aagctcacac ttgggctggc acccactgga ggtgggaaaa aaaaaaaaaa
2761 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//