LOCUS BC017033 2236 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens squalene epoxidase, mRNA (cDNA clone MGC:9087
IMAGE:3846346), complete cds.
ACCESSION BC017033
VERSION BC017033.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2236)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2236)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 20 Row: g Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 62865634.
FEATURES Location/Qualifiers
source 1..2236
/db_xref="H-InvDB:HIT000037799"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9087 IMAGE:3846346"
/tissue_type="Colon, adenocarcinoma"
/clone_lib="NIH_MGC_65"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2236
/gene="SQLE"
/db_xref="GeneID:6713"
/db_xref="HGNC:HGNC:11279"
/db_xref="MIM:602019"
CDS 159..1883
/gene="SQLE"
/codon_start=1
/product="squalene epoxidase"
/protein_id="AAH17033.1"
/db_xref="GeneID:6713"
/db_xref="HGNC:HGNC:11279"
/db_xref="MIM:602019"
/translation="MWTFLGIATFTYFYKKFGDFITLANREVLLCVLVFLSLGLVLSY
RCRHRNGGLLGRQQSGSQFALFSDILSGLPFIGFFWAKSPPESENKEQLEARRRRKGT
NISETSLIGTAACTSTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPD
RIVGEFLQPGGYHVLKDLGLGDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQV
QSGRAFHHGRFIMSLRKAAMAEPNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKEL
HAPLTVVADGLFSKFRKSLVSNKVSVSSHFVGFLMKNAPQFKANHAELILANPSPVLI
YQISSSETRVLVDIRGEMPRNLREYMVEKIYPQIPDHLKEPFLEATDNSHLRSMPASF
LPPSSVKKRGVLLLGDAYNMRHPLTGGGMTVAFKDIKLWRKLLKGIPDLYDDAAIFEA
KKSFYWARKTSHSFVVNILAQALYELFSATDDSLHQLRKACFLYFKLGGECVAGPVGL
LSVLSPNPLVLIGHFFAVAIYAVYFCFKSEPWITKPRALLSSGAVLYKACSVIFPLIY
SEMKYMVH"
BASE COUNT 631 a 447 c 495 g 663 t
ORIGIN
1 aaactggtct gatcggactt ctcgtcctgg gacactgttt actggagtct ggccggctct
61 ccgtgctcct cttggtacct cattttgggg agaaccttaa acccactcga gcagataatc
121 tccgccttga ccggtgccac caaagaagcc ttggaaccat gtggactttt ctgggcattg
181 ccactttcac ctatttttat aagaagttcg gggacttcat cactttggcc aacagggagg
241 tcctgttgtg cgtgctggtg ttcctctcgc tgggcctggt gctctcctac cgctgtcgcc
301 accgaaacgg gggtctcctc gggcgccagc agagcggctc ccagttcgcc ctcttctcgg
361 atattctctc aggcctgcct ttcattggct tcttctgggc caaatccccc cctgaatcag
421 aaaataagga gcagctcgag gccaggaggc gcagaaaagg aaccaatatt tcagaaacaa
481 gcttaatagg aacagctgcc tgtacatcaa catcttctca gaatgaccca gaagttatca
541 tcgtgggagc tggcgtgctt ggctctgctt tggcagctgt gctttccaga gatggaagaa
601 aggtgacagt cattgagaga gacttaaaag agcctgacag aatagttgga gaattcctgc
661 agccgggtgg ttatcatgtt ctcaaagacc ttggtcttgg agatacagtg gaaggtcttg
721 atgcccaggt tgtaaatggt tacatgattc atgatcagga aagcaaatca gaggttcaga
781 ttccttaccc tctgtcagaa aacaatcaag tgcagagtgg aagagctttc catcacggaa
841 gattcatcat gagtctccgg aaagcagcta tggcagagcc caatgcaaag tttattgaag
901 gtgttgtgtt acagttatta gaggaagatg atgttgtgat gggagttcag tacaaggata
961 aagagactgg agatatcaag gaactccatg ctccactgac tgttgttgca gatgggcttt
1021 tctccaagtt caggaaaagc ctggtctcca ataaagtttc tgtatcatct cattttgttg
1081 gctttcttat gaagaatgca ccacagttta aagcaaatca tgctgaactt attttagcta
1141 acccgagtcc agttctcatc taccagattt catccagtga aactcgagta cttgttgaca
1201 ttagaggaga aatgccaagg aatttaagag aatacatggt tgaaaaaatt tacccacaaa
1261 tacctgatca cctgaaagaa ccattcttag aagccactga caattctcat ctgaggtcca
1321 tgccagcaag cttccttcct ccttcatcag tgaagaaacg aggtgttctt cttttgggag
1381 acgcatataa tatgaggcat ccacttactg gtggaggaat gactgttgct tttaaagata
1441 taaaactatg gagaaaactg ctaaagggta tccctgacct ttatgatgat gcagctattt
1501 tcgaggccaa aaaatcattt tactgggcaa gaaaaacatc tcattccttt gtcgtgaata
1561 tccttgctca ggctctttat gaattatttt ctgccacaga tgattccctg catcaactaa
1621 gaaaagcctg ttttctttat ttcaaacttg gtggcgaatg tgttgcgggt cctgttgggc
1681 tgctttctgt attgtctcct aaccctctag ttttaattgg acacttcttt gctgttgcaa
1741 tctatgccgt gtatttttgc tttaagtcag aaccttggat tacaaaacct cgagcccttc
1801 tcagtagtgg tgctgtattg tacaaagcgt gttctgtaat atttcctcta atttactcag
1861 aaatgaagta tatggttcat taagcttaaa ggggaaccat ttgtgaatga atatttggaa
1921 cttaccaagt cctaagagac ttttggaaga ggatatatat agcatagtac cataccactt
1981 ataaagtgga aactcttgga ccaagatttg gattaatttg tttttgaagt tttttgtata
2041 taaatatgta aatacatgct ttaatttgca atttaaaatg aaggggttaa ataagttaga
2101 catttaaaag aaatgattgt taccataaat tagtgctaat gctgaggaga actacagttt
2161 ttcttttgaa tttagtattt gagatgagtt gttgggacat gcaaataaaa tgaagaatga
2221 aaaaaaaaaa aaaaaa
//