LOCUS BC016853 1689 bp mRNA linear HUM 06-OCT-2003
DEFINITION Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide
11, mRNA (cDNA clone MGC:16892 IMAGE:3846027), complete cds.
ACCESSION BC016853
VERSION BC016853.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1689)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1689)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 20 Row: g Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 10863992.
FEATURES Location/Qualifiers
source 1..1689
/db_xref="H-InvDB:HIT000037720"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:16892 IMAGE:3846027"
/tissue_type="Colon, adenocarcinoma"
/clone_lib="NIH_MGC_65"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1689
/gene="CYP4F11"
/db_xref="GeneID:57834"
CDS 37..1611
/gene="CYP4F11"
/codon_start=1
/product="CYP4F11 protein"
/protein_id="AAH16853.1"
/db_xref="GeneID:57834"
/translation="MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDN
CRRLQCFPQPPKQNWFWGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILC
HPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNIL
KPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKP
SEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRR
TLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTA
SGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLH
PPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENI
KERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEPRRKPELILRA
EGGLWLRVEPLGANSQ"
misc_feature 265..1578
/gene="CYP4F11"
/note="p450; Region: Cytochrome P450. Cytochrome P450s are
involved in the oxidative degradation of various
compounds. Particularly well known for their role in the
degradation of environmental toxins and mutagens.
Structure is mostly alpha, and binds a heme cofactor"
/db_xref="CDD:pfam00067"
BASE COUNT 392 a 495 c 439 g 363 t
ORIGIN
1 gaggcaaaga cctcctagca gagggggaga ggagggatgc cgcagctgag cctgtcctgg
61 ctgggcctcg ggcccgtggc agcatccccg tggctgcttc tgctgctggt tgggggctcc
121 tggctcctgg cccgcgtcct ggcctggacc tacaccttct atgacaactg ccgccgcctc
181 cagtgttttc ctcaaccccc gaaacagaac tggttttggg gacaccaggg cctggtcact
241 cccacggaag agggcatgaa gacattgacc cagctggtga ccacatatcc ccagggcttt
301 aagttgtggc tgggtcctac cttccccctc ctcattttat gccaccctga catcatccgg
361 cctatcacca gtgcctcagc tgctgtcgca cccaaggata tgattttcta tggcttcctg
421 aagccctggc tgggggatgg gctcctgctg agtggtggtg acaagtggag ccgccaccgt
481 cggatgttga cgcctgcctt ccatttcaac atcttgaagc cttatatgaa gattttcaac
541 aagagtgtga acatcatgca cgacaagtgg cagcgcctgg cctcagaggg cagcgccaga
601 ctggacatgt ttgaacacat cagcctcatg accttggaca gtctgcagaa atgtgtcttc
661 agctttgaaa gcaattgtca ggagaagccc agtgaatata ttgccgccat cttggagctc
721 agtgcctttg tagaaaagag aaaccagcag attctcttgc acacggactt cctgtattat
781 ctcactcctg atgggcagcg cttccgcagg gcctgccacc tggtgcacga cttcacagat
841 gccgtcatcc aggagcggcg ccgcaccctc cccactcagg gtattgatga tttcctcaag
901 aacaaggcaa agtccaagac tttagacttc attgatgtgc ttctgctgag caaggatgaa
961 gatgggaagg aattgtctga tgaggacata agagcagaag ctgacacctt catgtttgag
1021 ggccatgaca ctacagccag tggtctctcc tgggtcctat accaccttgc aaagcaccca
1081 gaataccagg aacagtgccg gcaagaagtg caagagcttc tgaaggaccg tgaacctata
1141 gagattgaat gggacgacct ggcccagctg cccttcctga ccatgtgcat taaggagagc
1201 ctgcggttgc atcccccagt cccggtcatc tcccgatgtt gcacgcagga ctttgtgctc
1261 ccagacggcc gcgtcatccc caaaggcatt gtctgcctca tcaatattat cgggatccat
1321 tacaacccaa ctgtgtggcc agaccctgag gtctacgacc ccttccgttt caaccaagag
1381 aacatcaagg agaggtcacc tctggctttt attcccttct cggcagggcc cagaaactgc
1441 atcgggcagg cgttcgccat ggctgagatg aaggtggtcc tggcgctcac gctgctgcac
1501 ttccgcatcc tgccgaccca cactgaaccc cgcaggaaac ccgagctgat attgcgcgca
1561 gagggtggac tttggctgcg ggtggagccc ctgggtgcga actcacagtg actgccctac
1621 ccacccaccc acctctgtag agtcccagaa acaaaactat gctgacaaaa aaaaaaaaaa
1681 aaaaaaaaa
//