LOCUS BC016671 2079 bp mRNA linear HUM 04-NOV-2003
DEFINITION Homo sapiens integrin, alpha 4 (antigen CD49D, alpha 4 subunit of
VLA-4 receptor), mRNA (cDNA clone IMAGE:4342576), partial cds.
ACCESSION BC016671
VERSION BC016671.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2079)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2079)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (31-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC016671.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 26 Row: k Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 6006032.
FEATURES Location/Qualifiers
source 1..2079
/db_xref="H-InvDB:HIT000089023"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4342576"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..>2079
/gene="ITGA4"
/gene_synonym="CD49d"
/db_xref="GeneID:3676"
/db_xref="MIM:192975"
CDS 229..>2079
/gene="ITGA4"
/gene_synonym="CD49d"
/codon_start=1
/product="ITGA4 protein"
/protein_id="AAH16671.1"
/db_xref="GeneID:3676"
/db_xref="MIM:192975"
/translation="MAWEARREPGPRRAAVRETVMLLLCLGVPTGRPYNVDTESALLY
QGPHNTLFGYSVVLHSHGANRWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCE
QLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNENKL
PTGGCYGVPPDLRTELSKRIAPCYQDYVKKFGENFASCQAGISSFYTKDLIVMGAPGS
SYWTGSLFVYNITTNKYKAFLDKQNQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHE
QIGKAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIR
EEGRVFVYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQ
EDDLQGAIYIYNGRADGISSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAV
GAFRSDSAVLLRTRPVVIVDASLSHPESVNRTKFDCVENGWPSVCIDLTLCFSYKGKE
VPGYIVLFYNMSLDVNRKAESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRK
DVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKKKK"
misc_feature 1135..1272
/gene="ITGA4"
/gene_synonym="CD49d"
/note="Int_alpha; Region: Integrin alpha (beta-propellor
repeats)"
/db_xref="CDD:smart00191"
misc_feature 1321..1476
/gene="ITGA4"
/gene_synonym="CD49d"
/note="Int_alpha; Region: Integrin alpha (beta-propellor
repeats)"
/db_xref="CDD:smart00191"
misc_feature 1510..1596
/gene="ITGA4"
/gene_synonym="CD49d"
/note="Int_alpha; Region: Integrin alpha (beta-propellor
repeats)"
/db_xref="CDD:smart00191"
BASE COUNT 571 a 462 c 527 g 519 t
ORIGIN
1 tccgggagtg gggccgggcg agtgcgcggc atcccaggcc ggcccgaacg ctccgcccgc
61 ggtgggccga cttcccctcc tcttccctct ctccttcctt tagcccgctg gcgccggaca
121 cgctgcgcct catctcttgg ggcgttcttc cccgttggcc aaccgtcgca tcccgtgcaa
181 ctttggggta gtggccgttt agtgttgaat gttccccacc gagagcgcat ggcttgggaa
241 gcgaggcgcg aacccggccc ccgaagggcc gccgtccggg agacggtgat gctgttgctg
301 tgcctggggg tcccgaccgg ccgcccctac aacgtggaca ctgagagcgc gctgctttac
361 cagggccccc acaacacgct gttcggctac tcggtcgtgc tgcacagcca cggggcgaac
421 cgatggctcc tagtgggtgc gcccactgcc aactggctcg ccaacgcttc agtgatcaat
481 cccggggcga tttacagatg caggatcgga aagaatcccg gccagacgtg cgaacagctc
541 cagctgggta gccctaatgg agaaccttgt ggaaagactt gtttggaaga gagagacaat
601 cagtggttgg gggtcacact ttccagacag ccaggagaaa atggatccat cgtgacttgt
661 gggcatagat ggaaaaatat attttacata aagaatgaaa ataagctccc cactggtggt
721 tgctatggag tgccccctga tttacgaaca gaactgagta aaagaatagc tccgtgttat
781 caagattatg tgaaaaaatt tggagaaaat tttgcatcat gtcaagctgg aatatccagt
841 ttttacacaa aggatttaat tgtgatgggg gccccaggat catcttactg gactggctct
901 ctttttgtct acaatataac tacaaataaa tacaaggctt ttttagacaa acaaaatcaa
961 gtaaaatttg gaagttattt aggatattca gtcggagctg gtcattttcg gagccagcat
1021 actaccgaag tagtcggagg agctcctcaa catgagcaga ttggtaaggc atatatattc
1081 agcattgatg aaaaagaact aaatatctta catgaaatga aaggtaaaaa gcttggatcg
1141 tactttggag cttctgtctg tgctgtggac ctcaatgcag atggcttctc agatctgctc
1201 gtgggagcac ccatgcagag caccatcaga gaggaaggaa gagtgtttgt gtacatcaac
1261 tctggctcgg gagcagtaat gaatgcaatg gaaacaaacc tcgttggaag tgacaaatat
1321 gctgcaagat ttggggaatc tatagttaat cttggcgaca ttgacaatga tggctttgaa
1381 gatgttgcta tcggagctcc acaagaagat gacttgcaag gtgctattta tatttacaat
1441 ggccgtgcag atgggatctc gtcaaccttc tcacagagaa ttgaaggact tcagatcagc
1501 aaatcgttaa gtatgtttgg acagtctata tcaggacaaa ttgatgcaga taataatggc
1561 tatgtagatg tagcagttgg tgcttttcgg tctgattctg ctgtcttgct aaggacaaga
1621 cctgtagtaa ttgttgacgc ttctttaagc caccctgagt cagtaaatag aacgaaattt
1681 gactgtgttg aaaatggatg gccttctgtg tgcatagatc taacactttg tttctcatat
1741 aagggcaagg aagttccagg ttacattgtt ttgttttata acatgagttt ggatgtgaac
1801 agaaaggcag agtctccacc aagattctat ttctcttcta atggaacttc tgacgtgatt
1861 acaggaagca tacaggtgtc cagcagagaa gctaactgta gaacacatca agcatttatg
1921 cggaaagatg tgcgggacat cctcacccca attcagattg aagctgctta ccaccttggt
1981 cctcatgtca tcagtaaacg aagtacagag gaattcccac cacttcagcc aattcttcag
2041 cagaagaaag aaaaagacat aatgaaaaaa aaaaaaaaa
//