LOCUS BC016451 3278 bp mRNA linear HUM 09-SEP-2005
DEFINITION Homo sapiens ADAM metallopeptidase with thrombospondin type 1
motif, 3, mRNA (cDNA clone IMAGE:3451933), partial cds.
ACCESSION BC016451
VERSION BC016451.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3278)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3278)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 19 Row: e Column: 19.
FEATURES Location/Qualifiers
source 1..3278
/db_xref="H-InvDB:HIT000088996"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3451933"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_10"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..3278
/gene="ADAMTS3"
/gene_synonym="ADAMTS-4"
/gene_synonym="KIAA0366"
/db_xref="GeneID:9508"
/db_xref="MIM:605011"
CDS <1..1095
/gene="ADAMTS3"
/gene_synonym="ADAMTS-4"
/gene_synonym="KIAA0366"
/codon_start=1
/product="ADAMTS3 protein"
/protein_id="AAH16451.1"
/db_xref="GeneID:9508"
/db_xref="MIM:605011"
/translation="EELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSF
CEANKKPKPIRRMCNIQECTHPLWVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTNR
SVHSKYCMGDRPESRRPCNRVPCPAQWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDG
EKPESVRACQLPPCNDEPCLGDKSIFCQMEVLARYCSIPGYNKLCCESCSKRSSTLPP
PYLLEAAETHDDVISNPSDLPRSLVMPTSLVPYHSETPAKKMSLSSISSVGGPNAYAA
FRPNSKPDGANLRQRSAQQAGSKTVRLVTVPSSPPTKRVHLSSASQMAAASFFAASDS
IGASSQARTSKKDGKIIDNRRPTRSSTLER"
BASE COUNT 1045 a 602 c 648 g 983 t
ORIGIN
1 gaagaattag atacttttga gtgggctttg aagagctggt ctcagtgttc caaaccctgt
61 ggtggaggtt tccagtacac taaatatgga tgccgtagga aaagtgataa taaaatggtc
121 catcgcagct tctgtgaggc caacaaaaag ccgaaaccta ttagacgaat gtgcaatatt
181 caagagtgta cacatccact ctgggtagca gaagaatggg aacactgcac caaaacctgt
241 ggaagttctg gctatcagct tcgcactgta cgctgccttc agccactcct tgatggcacc
301 aaccgctctg tgcacagcaa atactgcatg ggtgaccgtc ccgagagccg ccggccctgt
361 aacagagtgc cctgccctgc acagtggaaa acaggaccct ggagtgagtg ttcagtgacc
421 tgcggtgaag gaacggaggt gaggcaggtc ctctgcaggg ctggggacca ctgtgatggt
481 gaaaagcctg agtcggtcag agcctgtcaa ctgcctcctt gtaatgatga accatgtttg
541 ggagacaagt ccatattctg tcaaatggaa gtgttggcac gatactgctc cataccaggt
601 tataacaagt tatgttgtga gtcctgcagc aagcgcagta gcaccctgcc accaccatac
661 cttctagaag ctgctgaaac tcatgatgat gtcatctcta accctagtga cctccctaga
721 tctctagtga tgcctacatc tttggttcct tatcattcag agacccctgc aaagaagatg
781 tctttgagta gcatctcttc agtgggaggt ccaaatgcat atgctgcttt caggccaaac
841 agtaaacctg atggtgctaa tttacgccag aggagtgctc agcaagcagg aagtaagact
901 gtgagactgg tcaccgtacc atcctcccca cccaccaaga gggtccacct cagttcagct
961 tcacaaatgg ctgctgcttc cttctttgca gccagtgatt caataggtgc ttcttctcag
1021 gcaagaacct caaagaaaga tggaaagatc attgacaaca gacgtccgac aagatcatcc
1081 accttagaaa gatgagaaag tgaaccaaaa aggctagaaa ccagaggaaa acctggacaa
1141 cctctctctt cccatggtgc atatgcttgt ttaaagtgga aatctctata gatcgtcagc
1201 tcattttatc tgtaattgga agaacagaaa gtgctggctc actttctagt tgctttcatc
1261 ctccttttgt tctgcattga ctcatttacc agaattcatt ggaagaaatc accaaagatt
1321 attacaaaag aaaaatatgt tgctaagatt gtgttggtcg ctctctgaag cagaaaaggg
1381 actggaacca attgtgcata tcagctgact ttttgtttgt tttagaaaag ttacagtaaa
1441 aattaaaaag agataccaat ggtttacact ttaacaagaa attttggata tggaacaaag
1501 aattcttaga cttgtattcc tatttatcta tattagaaat attgtatgag caaatttgca
1561 gctgttgtgt aaatactgta tattgcaaaa atcagtatta ttttaagaga tgtgttctca
1621 aatgattgtt tactatatta catttctgga tgttctaggt gcctgtcgtt gagtattgcc
1681 ttgtttgaca ttctataggt taattttcaa agcagagtat tacaaaagag aagttagaat
1741 tacagctact gacaatataa agggttttgt tgaatcaaca atgtgatacg taaattatag
1801 aaaaagaaaa gaaacacaaa agctatagat atacagatat cagcttacct attgccttct
1861 atacttataa tttaaaggat tggtgtctta gtacacttgt ggtcacaggg atcaacgaat
1921 agtaaataat gaactcgtgc aagacaaaac tgaaaccctc tttccaggac ctcagtaggc
1981 accgttgagg tgtcctttgt ttttgtgtgt gtgtgttctt ttttaatttt cgcattgttg
2041 acagatacaa acagttatac tcaatgtact gtaataatcg caaaggaaaa agttttggga
2101 taacttattt gtatgttggt agctgagaaa aatatcatca gtctagaatt gatatttgag
2161 tatagtagag ctttggggct ttgaaggcag gttcaagaaa gcatatgtcg atggttgaga
2221 tatttatttt ccatatggtt catgttcaaa tgttcacaac cacaatgcat ctgactgcaa
2281 taatgtgcta ataatttatg tcagtagtca ccttgctcac agcaaagcca gaaatgctct
2341 ctccagggag tagatgtaaa gtacttgtac atagaattca gaactgaaga tatttattaa
2401 aagttgattt ttttttcttg atagtatttt tatgtactaa atatttacac taatatcaat
2461 tacatatttt ggtaaactag agagacataa ttagagatgc atgctttgtt ctgtgcatag
2521 agacctttaa gcaaactact acagccaact caaaagctaa aactgaacaa atttgatgtt
2581 atgcaaacat cttgcatttt tagtagttga tattaagttg atgacttgtt tcccttcaag
2641 gaaacattaa attgtatgga ctcagctagc tgttcaatga aattgtgaat tagaaacatt
2701 tttaaaagtt tttgaaagag ataagtgcat catgaattac atgtacatga gaggagatag
2761 tgatatcagc ataatgattt tgaggtcagt acctgagctg tctaaaaata tattatacaa
2821 actaaaatgt agatgaatta acctctcaaa gcacagaatg tgcaagaact tttgcatttt
2881 aatcgttgta aactaacagc ttaaactatt gactctatac ctctaaagaa ttgctgctac
2941 tttgtgcaag aactttgaag gtcaaattag gcaaattcca gatagtaaaa caatccctaa
3001 gccttaagtc tttttttttt tcctaaaaat tcccatagaa taaaattctc tctagtttac
3061 ttgtgtgtgc atacatctca tccacagggg aagataaaga tggtcacaca aacagtttcc
3121 ataaagatgt acatattcat tatacttctg acctttgggc tttcttttct actaagctaa
3181 aaattccttt ttatcaaagt gtacactact gatgctgttt gttgtactga gagcacgtac
3241 caataaaaat gttaacaaaa tataaaaaaa aaaaaaaa
//