LOCUS BC015958 2777 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens poly(A) binding protein, cytoplasmic 1, mRNA (cDNA
clone MGC:15290 IMAGE:3940309), complete cds.
ACCESSION BC015958
VERSION BC015958.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2777)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2777)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (22-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC015958.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 25 Row: e Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4505574.
FEATURES Location/Qualifiers
source 1..2777
/db_xref="H-InvDB:HIT000037423"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:15290 IMAGE:3940309"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2777
/gene="PABPC1"
/gene_synonym="PAB1"
/gene_synonym="PABP"
/gene_synonym="PABP1"
/gene_synonym="PABPL1"
/db_xref="GeneID:26986"
/db_xref="MIM:604679"
CDS 400..2310
/gene="PABPC1"
/gene_synonym="PAB1"
/gene_synonym="PABP"
/gene_synonym="PABP1"
/gene_synonym="PABPL1"
/codon_start=1
/product="PABPC1 protein"
/protein_id="AAH15958.1"
/db_xref="GeneID:26986"
/db_xref="MIM:604679"
/translation="MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCR
DMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIF
IKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG
MLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPAL
SVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTEL
KRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKG
FGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAV
PNPVINPYQPAPPSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNM
PGAIRPAAPRPPFSTMRPASSQVPRVMSTQRVANTSTQTMGPRPAAAAAAATPAVRTV
PQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERL
FPLIQAMHPTLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQ
KAVNSATGVPTV"
misc_feature 643..1515
/gene="PABPC1"
/gene_synonym="PAB1"
/gene_synonym="PABP"
/gene_synonym="PABP1"
/gene_synonym="PABPL1"
/note="COG0724; Region: RNA-binding proteins (RRM domain)
[General function prediction only]"
/db_xref="CDD:COG0724"
misc_feature 2029..2241
/gene="PABPC1"
/gene_synonym="PAB1"
/gene_synonym="PABP"
/gene_synonym="PABP1"
/gene_synonym="PABPL1"
/note="Region: Poly-adenylate binding protein, unique
domain"
/db_xref="CDD:pfam00658"
BASE COUNT 850 a 646 c 596 g 685 t
ORIGIN
1 gagagtgcgg agtgtgtgct ccgggctcgg aacacacatt tattattaaa aaatccaaaa
61 aaaatctaaa aaaatctttt aaaaaacccc aaaaaaaaat ttacaaaaaa tccgcgtctc
121 ccccgccgga gacttttatt ttttttcttc ctcttttata aaataacccg gtgaagcagc
181 cgagaccgac cctcgctccc cgccggcagc cggcagccag cggcagtgga tcgaccccgt
241 tctgcggccg ttgagtagtt ttcaattccg gttgattttt gtccctctgc gcttgctccc
301 cgctcccctc cccccggctc cggcccccag ccccggcact cgctctcctc ctctcacgga
361 aaggtcgcgg cctgtggccc tgcgggcagc cgtgccgaga tgaaccccag tgcccccagc
421 taccccatgg cctcgctcta cgtgggggac ctccaccccg acgtgaccga ggcgatgctc
481 tacgagaagt tcagcccggc cgggcccatc ctctccatcc gggtctgcag ggacatgatc
541 acccgccgct ccttgggcta cgcgtatgtg aacttccagc agccggcgga cgcggagcgt
601 gctttggaca ccatgaattt tgatgttata aagggcaagc cagtacgcat catgtggtct
661 cagcgtgatc catcacttcg caaaagtgga gtaggcaaca tattcattaa aaatctggac
721 aaatccattg ataataaagc actgtatgat acattttctg cttttggtaa catcctttca
781 tgtaaggtgg tttgtgatga aaatggttcc aagggctatg gatttgtaca ctttgagacg
841 caggaagcag ctgaaagagc tattgaaaaa atgaatggaa tgctcctaaa tgatcgcaaa
901 gtatttgttg gacgatttaa gtctcgtaaa gaacgagaag ctgaacttgg agctagggca
961 aaagaattca ccaatgttta catcaagaat tttggagaag acatggatga tgagcgcctt
1021 aaggatctct ttggcaagtt tgggcctgcc ttaagtgtga aagtaatgac tgatgaaagt
1081 ggaaaatcca aaggatttgg atttgtaagc tttgaaaggc atgaagatgc acagaaagct
1141 gtggatgaga tgaacggaaa ggagctcaat ggaaaacaaa tttatgttgg tcgagctcag
1201 aaaaaggtgg aacggcagac ggaacttaag cgcaaatttg aacagatgaa acaagatagg
1261 atcaccagat accagggtgt taatctttat gtgaaaaatc ttgatgatgg tattgatgat
1321 gaacgtctcc ggaaagagtt ttctccattt ggtacaatca ctagtgcaaa ggttatgatg
1381 gagggtggtc gcagcaaagg gtttggtttt gtatgtttct cctccccaga agaagccact
1441 aaagcagtta cagaaatgaa cggtagaatt gtggccacaa agccattgta tgtagcttta
1501 gctcagcgca aagaagagcg ccaggctcac ctcactaacc agtatatgca gagaatggca
1561 agtgtacgag ctgttcccaa ccctgtaatc aacccctacc agccagcacc tccttcaggt
1621 tacttcatgg cagctatccc acagactcag aaccgtgctg catactatcc tcctagccaa
1681 attgctcaac taagaccaag tcctcgctgg actgctcagg gtgccagacc tcatccattc
1741 caaaatatgc ccggtgctat ccgcccagct gctcctagac caccatttag tactatgaga
1801 ccagcttctt cacaggttcc acgagtcatg tcaacacagc gtgttgctaa cacatcaaca
1861 cagacaatgg gtccacgtcc tgcagctgca gccgctgcag ctactcctgc tgtccgcacc
1921 gttccacagt ataaatatgc tgcaggagtt cgcaatcctc agcaacatct taatgcacag
1981 ccacaagtta caatgcaaca gcctgctgtt catgtacaag gtcaggaacc tttgactgct
2041 tccatgttgg catctgcccc tcctcaagag caaaagcaaa tgttgggtga acggctgttt
2101 cctcttattc aagccatgca ccctactctt gctggtaaaa tcactggcat gttgttggag
2161 attgataatt cagaacttct tcatatgctc gagtctccag agtcactccg ttctaaggtt
2221 gatgaagctg tagctgtact acaagcccac caagctaaag aggctgccca gaaagcagtt
2281 aacagtgcca ccggtgttcc aactgtttaa aattgatcag ggaccatgaa aagaaacttg
2341 tgcttcaccg aagaaaaata tctaaacatc gaaaaactta aatattatgg aaaaaaaaca
2401 ttgcaaaata taaaataaat aaaaaaagga aaggaaactt tgaaccttat gtaccgagca
2461 aatgccaggt ctagcaaaca taatgctagt cctagattac ttattgattt aaaaacaaaa
2521 aaacacaaaa aaatagtaaa atataaaaac aaattaatgt tttatagacc ctgggaaaaa
2581 gaattttcag caaagtacaa aaatttaaag cattcctttc tttaattttg taattcttta
2641 ctgtggaata gctcagaatg tcagttctgt tttaagtaac agaattgata actgagcaag
2701 gaaacgtaat ttggattata aaattcttgc tttaataaaa attccttaaa cagtgcaaaa
2761 aaaaaaaaaa aaaaaaa
//