LOCUS BC015923 2602 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens kelch-like 22 (Drosophila), mRNA (cDNA clone MGC:20518
IMAGE:4562420), complete cds.
ACCESSION BC015923
VERSION BC015923.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2602)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2602)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 29 Row: f Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24432025.
FEATURES Location/Qualifiers
source 1..2602
/db_xref="H-InvDB:HIT000037399"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20518 IMAGE:4562420"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2602
/gene="KLHL22"
/gene_synonym="KELCHL"
/db_xref="GeneID:84861"
/db_xref="HGNC:HGNC:25888"
CDS 110..2014
/gene="KLHL22"
/gene_synonym="KELCHL"
/codon_start=1
/product="kelch-like 22 (Drosophila)"
/protein_id="AAH15923.1"
/db_xref="GeneID:84861"
/db_xref="HGNC:HGNC:25888"
/translation="MAEEQEFTQLCKLPAQPSHPHCVNNTYRSAQHSQALLRGLLALR
DSGILFDVVLVVEGRHIEAHRILLAASCDYFRGMFAGGLKEMEQEEVLIHGVSYNAMC
QILHFIYTSELELSLSNVQETLVAACQLQIPEIIHFCCDFLMSWVDEENILDVYRLAE
LFDLSRLTEQLDTYILKNFVAFSRTDKYRQLPLEKVYSLLSSNRLEVSCETEVYEGAL
LYHYSLEQVQADQISLHEPPKLLETVRFPLMEAEVLQRLHDKLDPSPLRDTVASALMY
HRNESLQPSLQSPQTELRSDFQCVVGFGGIHSTPSTVLSDQAKYLNPLLGEWKHFTAS
LAPRMSNQGIAVLNNFVYLIGGDNNVQGFRAESRCWRYDPRHNRWFQIQSLQQEHADL
SVCVVGRYIYAVAGRDYHNDLNAVERYDPATNSWAYVAPLKREVYAHAGATLEGKMYI
TCGRRGEDYLKETHCYDPGSNTWHTLADGPVRRAWHGMATLLNKLYVIGGSNNDAGYR
RDVHQVACYSCTSGQWSSVCPLPAGHGEPGIAVLDNRIYVLGGRSHNRGSRTGYVHIY
DVEKDCWEEGPQLDNSISGLAACVLTLPRSLLLEPPRGTPDRSQADPDFASEVMSVSD
WEEFDNSSED"
BASE COUNT 548 a 776 c 764 g 514 t
ORIGIN
1 ccgcctcgcg cctcccgcct cccgcctccc gcctccctcc agctgcgagt gcggcctcgg
61 ctggcggcgg caccaggcca cagttgtaag ggatcttgtg gctgtcagga tggcagagga
121 gcaggagttc acccagctct gcaagttgcc tgcacagccc tcacacccac actgcgtgaa
181 caacacctac cgcagcgcac agcactccca ggctctgctc cgagggctgc tggctctccg
241 ggacagcgga atcctcttcg atgttgtgct ggtggtggag ggcagacaca tcgaggccca
301 tcgcatcctg ctggctgcgt cctgcgatta cttcagagga atgtttgctg ggggattgaa
361 ggagatggaa caggaagagg tcctgatcca cggtgtgtcc tacaatgcta tgtgccaaat
421 cctacatttc atatacacct ccgagctgga gctcagcctg agcaatgtac aagagacact
481 ggtggctgcc tgccagcttc agatcccaga aattatccat ttctgctgtg atttcctcat
541 gtcctgggtg gacgaagaga acattctcga tgtctaccgg ctggcagagc tgtttgactt
601 gagccgcctg actgagcaac tggacaccta tatcctcaaa aactttgtgg ccttctctcg
661 gactgacaag taccgccagc ttccattgga gaaggtctac tccctcctca gcagcaatcg
721 cctggaggtc tcctgcgaga ccgaggtata tgagggggcc cttctctacc attatagcct
781 ggagcaggtg caggctgacc agatctcgct gcacgagccc ccaaagctcc ttgagacagt
841 gcggtttccg ctgatggaag ctgaggtcct gcagcggctg catgacaagc tggaccccag
901 ccctttgagg gacacagtgg ccagcgccct catgtaccac cggaacgaga gcctacagcc
961 cagcctgcag agcccgcaaa cggagctgcg gtcggacttc cagtgcgttg tgggcttcgg
1021 gggcattcac tccacgccgt ccactgtcct cagcgaccag gccaagtatc taaacccctt
1081 actgggagag tggaagcact tcactgcctc cctggccccc cgcatgtcca accagggcat
1141 cgcggtgctc aacaacttcg tatacttgat tggaggggac aacaatgtcc aaggatttcg
1201 agcagagtcc cgatgctgga ggtatgaccc acggcacaac cgctggttcc agatccagtc
1261 cctgcagcag gagcacgccg acctgtccgt gtgtgttgta ggcaggtaca tctacgctgt
1321 ggcgggccgt gactaccaca atgacctgaa tgctgtggag cgctacgacc ctgccaccaa
1381 ctcctgggca tacgtggccc cactcaagag ggaggtgtat gcccacgcag gcgcgacgct
1441 ggaggggaag atgtatatca cctgcggccg cagaggggag gattacctga aagagacaca
1501 ctgctacgat ccaggcagca acacttggca cacactggct gatgggcctg tgcggcgcgc
1561 ctggcacggc atggcaaccc tcctcaacaa gctgtatgtg atcgggggca gcaacaacga
1621 tgccggatac aggagggacg tgcaccaggt ggcctgctac agctgcacgt ctggacagtg
1681 gtcatctgtc tgcccactcc ctgctgggca cggtgagcct ggcattgctg tgctggacaa
1741 caggatctat gtgttaggtg gccgctcaca caaccgcggc agccgcacag gctacgtgca
1801 catttacgat gtggagaagg actgctggga ggaagggccc cagctggaca actccatctc
1861 aggcctggcg gcctgtgtgc tcaccctgcc ccgctccctg ctccttgagc cgccccgcgg
1921 gacccctgac cgcagccagg ccgacccgga ctttgcctct gaggtgatga gtgtgtctga
1981 ctgggaggag tttgacaact ccagtgagga ctaggctccc tgtgcctggc atcagaggga
2041 agggaggctg gggctgcagg gcagtgaaac ccacgcagcc taggccagag cactttactc
2101 caggcagggc ccctgcccct gttggccaca gcttatgggc cctgccctct ttcttcacac
2161 cagccccttg gccagcctgc cgcaggcatc tcagggccat gcagatccca ggctgtggat
2221 tacgtcactg caggaactgc ttctgaaagg ctttggcctt cctcagtgag ccctggaggg
2281 gttggccttc tctcctccct gcctagatca gtccttctcc aaaaggacct gggagctggc
2341 agcctgggca ggggggctga ggcacgtggt agccctcttt ctgtgaatgg ggtggggctg
2401 tgggggcagc tggggttgga ggatgagagc tcctgagggg cagaggagca gagatgcatc
2461 agctcgcctg ggactggctc tgtgataaaa agacccctcc cgctgggttt tcagacccca
2521 tgttgttggt caatgaaata aagcatctta cagaaggtgt taactgttaa aaaaaaaaaa
2581 aaaaaaaaaa aaaaaaaaaa aa
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