LOCUS BC015807 1819 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cystathionase (cystathionine gamma-lyase), mRNA (cDNA
clone MGC:9471 IMAGE:3915913), complete cds.
ACCESSION BC015807
VERSION BC015807.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1819)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1819)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC015807.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 15 Row: k Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34328937.
FEATURES Location/Qualifiers
source 1..1819
/db_xref="H-InvDB:HIT000037338"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9471 IMAGE:3915913"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1819
/gene="CTH"
/gene_synonym="MGC9471"
/db_xref="GeneID:1491"
/db_xref="HGNC:HGNC:2501"
/db_xref="MIM:607657"
CDS 145..1362
/gene="CTH"
/gene_synonym="MGC9471"
/codon_start=1
/product="cystathionase (cystathionine gamma-lyase)"
/protein_id="AAH15807.1"
/db_xref="GeneID:1491"
/db_xref="HGNC:HGNC:2501"
/db_xref="MIM:607657"
/translation="MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLS
TTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLK
AGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPT
NPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHS
DVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAV
AQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKL
FTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQ
ALKAAHPPSGSHS"
BASE COUNT 484 a 384 c 384 g 567 t
ORIGIN
1 ctttagtgcg ctcgccgtcg gctctacctg cgtgctttag ctccttctcg cctgatcctt
61 ctgtctctcc caaccccgga cacccggctt cgactggtta tatcttcggt gttcttttcc
121 tctcttcttc tttcgcggtt cagcatgcag gaaaaagacg cctcctcaca aggtttcctg
181 ccacacttcc aacatttcgc cacgcaggcg atccatgtgg gccaggatcc agagcaatgg
241 acctccaggg ctgtagtgcc ccccatctca ctgtccacca cgttcaagca aggggcgcct
301 ggccagcact cgggttttga atatagccgt tctggaaatc ccactaggaa ttgccttgaa
361 aaagcagtgg cagcactgga tggggctaag tactgtttgg cctttgcttc aggtttagca
421 gccactgtaa ctattaccca tcttttaaaa gcaggagacc aaattatttg tatggatgat
481 gtgtatggag gtacaaacag gtacttcagg caagtggcat ctgaatttgg attaaagatt
541 tcttttgttg attgttccaa aatcaaatta ctagaggcag caattacacc agaaaccaag
601 cttgtttgga tcgaaacccc cacaaacccc acccagaagg tgattgacat tgaaggctgt
661 gcacatattg tccataagca tggagacatt attttggtcg tggataacac ttttatgtca
721 ccatatttcc agcgcccttt ggctctggga gctgatattt ctatgtattc tgcaacaaaa
781 tacatgaatg gccacagtga tgttgtaatg ggcctggtgt ctgttaattg tgaaagcctt
841 cataatagac ttcgtttctt gcaaaactct cttggagcag ttccatctcc tattgattgt
901 tacctctgca atcgaggtct gaagactcta catgtccgaa tggaaaagca tttcaaaaac
961 ggaatggcag ttgcccagtt cctggaatct aatccttggg tagaaaaggt tatttatcct
1021 gggctgccct ctcatccaca gcatgagttg gtgaagcgtc agtgtacagg ttgtacaggg
1081 atggtcacct tttatattaa gggcactctt cagcatgctg agattttcct caagaaccta
1141 aagctattta ctctggccga gagcttggga ggattcgaaa gccttgctga gcttccggca
1201 atcatgactc atgcatcagt tcttaagaat gacagagatg tccttggaat tagtgacaca
1261 ctgattcgac tttctgtggg cttagaggat gaggaagacc tactggaaga tctagatcaa
1321 gctttgaagg cagcacaccc tccaagtgga agtcacagct agtattccag agctgctatt
1381 agaagctgct tcctgtgaag atcaaatctt cctgagtaat taaatggacc aacaatgagc
1441 ctttgcaaaa ttttcaagcg gaaattttaa ggcacctcat tatctttcat aactgtaatt
1501 ttcttaggga tcatctctgt taaaaagttt tctgtatgtc atgttataat tacaggtcaa
1561 ttctgttaat atctttttgt taattttgct ctatgtttgc ctctgaagga ggtgagattt
1621 gtgctacttt gggagattat gttctttttt catgtctaag atttattttg atcatgttta
1681 taatataatg gtaattcatt tttgatgttt tgtgaagaat ttaaatttaa acgaatgttc
1741 ttaaatcaag tgtgattttt ttgcatatca ttgaaaagaa cattaaaagc aatggtttac
1801 acttaaaaaa aaaaaaaaa
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